This question examines the pharmacist's communication with other health care providers. In general, systolic and diastolic blood pressures rise rapidly from morning and peak at 9-10 a.m., while they begin to decrease in the evening and fall to a trough during sleep, which is known as arytenoid hypertension; while a small number of patients (about 10%), due to abnormal circadian rhythms of blood pressure, atherosclerosis, and left heart insufficiency, have nighttime blood pressures that do not decrease or even are higher than the daytime blood pressure, and the fluctuations of blood pressure show a nonarytenoidal curve, which is known as nonarytenoidal hypertension. For patients with aryepiglottic hypertension, the best time to take long-acting anti-hypertensive drugs is around 7:00 a.m. if they take long-acting anti-hypertensive drugs only once a day; if they take intermediate-acting anti-hypertensive drugs, they should be taken twice a day, at 7:00 a.m. and 3~6:00 p.m. It is not advisable to take drugs before bedtime or at night to avoid low blood pressure, causing insufficient circulating blood flow and oxygen perfusion, which may easily lead to the occurrence of ischemic stroke. For patients with non arytenoid hypertension, the medication can be taken at night before going to bed, which can better correct the high blood pressure at night. Some anti-cold medicines contain an ingredient that reduces nasal congestion, such as pseudoephedrine, etc. These medicines can constrict blood vessels, causing elevated blood pressure, headache, hypertension and other cardiovascular diseases patients to avoid taking. Antihypertensive drugs are also known as "maintenance drugs" and must be taken consistently.