Regulating qi is broad and moderate, and stagnation and bloating are eliminated. Used for chest and hypochondriac qi stagnation, fullness and pain, indigestion, phlegm retention; Gastroptosis, proctoptosis, prolapsed genitals.
Compendium of Materia Medica: Fructus Aurantii Immaturus and Fructus Aurantii have the same smell and function, and there is no difference in the last world. Since Wei and Jin dynasties, they have been divided into solid and shell functions. Jie Gu Zhang, Dong Yuan Li, and divide and rule under Gao Zhi. Generally speaking, all its functions can benefit qi, and phlegm and asthma will stop when qi goes down, and the general principle of qi will stop the pain, and then it will be removed. Therefore, Fructus Aurantii Immaturus will benefit the chest diaphragm and the stomach. However, Zhang Zhongjing treats chest stuffiness and fullness with Fructus Aurantii Immaturus as the main medicine, and various prescriptions treat bloody hemorrhoid and dysentery, secret obstruction of the large intestine, and the acute interior is heavy, and with Fructus Aurantii as the general principle, so Fructus Aurantii Immaturus will not only treat it. Cover from the flying gate to the soul gate, all of which are dominated by the lung, and the three jiao are interlinked, so that the two things can be divided into two parts, regardless of whether they are hurt or not.
Du Renfang contains thin fetus drink, while Zhang Gugu's "The Secret of Living Method" is changed to take Zhi Shu Pill daily, which makes the fetus thin and easy to live, so it is called bundle fetus pill. And Kou Zongshuang
"Yan Yi" said that a strong fetus makes the child strong and easy to live, which makes the child take bitter orange medicine, which leads to weakness, and the child is also weak and difficult to raise. The so-called abortion is easy to give birth, but it is not the same. Based on rational thinking, Kou's theory seems to be superior, or it should be used by those who are full of qi before pregnancy. The so-called August and September pregnancy must use bitter orange and Su terrier to smooth the qi, and there is no stagnation before pregnancy, so there is no deficiency after childbirth. If you are angry with the weak, it is a big mistake.
Herbal Classic Shu: Fructus Aurantii, which is dominated by smell, is roughly the same as Fructus Aurantii Immaturus. However, Fructus Aurantii Immaturus is small in shape, full of qi and strong in nature, so it is good to give it; The shape of Fructus Aurantii is large, its qi is scattered, and its nature is slow, so its travel is a little late, which is based on the division of the chest, diaphragm, lung and stomach into the large intestine. For those who treat wind itching and paralysis, dredge joints and stop wind pain, cover the lung to control fur and stomach to control muscles. When wind, cold and dampness enter the two meridians, the skin will be itchy, painful or numb. This medicine has the function of relieving bitterness and dispersing pungent substances, and it can also induce various wind drugs to enter the two viscera, so it is necessary to treat wind. When common cold is dispersed, the joints will naturally dredge. It is used to treat cough due to fatigue and fatigue, and the cover also means that the wind and cold are depressed in the upper energizer, so the lung qi is stagnant and the cough is caused by fatigue.
"Jing" says: the lung is bitter and the gas goes up against it, so it is urgent to eat bitterness to vent it, and the bitter taste of bitter orange can vent the highest gas, so it is also the Lord's. The lung and the large intestine are exterior and interior, and common cold enters the lung, then it merges into the large intestine. Wind and heat fight each other, and blood flows from the intestinal wind, and gas flows from bitter cold, then the blood and heat are clear and the wind is removed. Its main principle is to disperse and retain phlegm stagnation in the chest and diaphragm, expel water, eliminate fullness and soothe the stomach, which is the same as that of Fructus Aurantii Immaturus. First, its qi slows the ears slightly. ""In this world, it is mostly used to treat women's fetal distress, or it is an easy-to-give-birth agent in August and September, but I don't know that when a woman is pregnant, it depends entirely on qi and blood to support the fetus. When qi and blood are sufficient, the fetus is easy to give birth, and the pregnant woman is sleepy in August and September, her limbs are weak, her diet is reduced, and her breathing is fast.
The function of Fructus Aurantii:
1, increasing coronary flow and renal blood bleeding, and reducing myocardial oxygen consumption by intravenous injection of 0.02-0.5mg/kg in anesthetized dogs all showed pressor effect, with large dose and obvious pressor effect. Intravenous infusion of 0.2mg/kg per minute; Renal blood flow increased by 75% and urine volume doubled. It has a strong effect on inducing myocardial rhythm, and its intensity is equivalent to adrenaline, but stronger than dopamine and synephrine. Synephrine contained in Fructus Aurantii is an adrenergic a- receptor stimulant, and it also has a certain exciting effect on cardiac B- receptor. It can contract blood vessels and raise blood pressure. Effects on blood flow of heart, brain and kidney, etc. Intravenous injection of Fructus Aurantii Immaturus (every 1ml=4g crude drug) 1ml/kg can significantly increase cerebral blood flow. After injection, the cerebral blood flow increased by 82.6 20.56 ml/100g brain weight/min (P <: 0.0 1)。 The average increase is equivalent to 86.4% of cerebral blood flow before injection. The cerebrovascular resistance index decreased by 0.428 0.12 on average (p <: 0.0 1), which can significantly reduce the cerebrovascular resistance. Intravenous drip 1.5ml/kg has no obvious effect on cerebral blood flow. Intravenous injection of Fructus Aurantii Immaturus 1.5ml/kg in anesthetized dogs can significantly increase renal blood flow, with an average increase of 64.5 9.4ml/100g renal weight/min (P < 0.0 1), the average increase was equivalent to 53.9% of the renal blood flow before injection, and the renal vascular resistance index decreased by 0.519 0.176 (P < 0.05), it can significantly reduce the renal vascular resistance, but the same dose of intravenous drip has no obvious effect. After intravenous injection of the above doses, the blood pressure increased, while the femoral artery blood flow decreased, the average decrease was 4 1.3% of that before medication, and the vascular resistance also increased.
2, diuretic effect
Intravenous injection of Fructus Aurantii Immaturus injection and N- methylttyramine in dogs can obviously increase urine output, and at the same time, blood pressure and renal vascular resistance are obviously increased. Its diuretic effect may be produced by inhibiting renal tubular reabsorption and other effects. Another study thinks that Fructus Aurantii Immaturus can exert the effect of sodium excretion and diuresis by strengthening the heart to contract renal blood vessels and increasing filtration pressure.
3. Effect on gastrointestinal smooth muscle
The decoction of Fructus Aurantii Immaturus has inhibitory effect on the isolated intestine of mice, while the isolated intestine of rabbits has all inhibitory effects. This effect can be antagonized by acetylcholine. However, after gavage with 100% Fructus Aurantii Immaturus in dogs with gastric flaccidity and intestinal flaccidity, it has an exciting effect and can increase the contraction rhythm of gastrointestinal motility. After gavage 100% concentrated Fructus Aurantii Immaturus solution 1ml/kg to dogs, it can be seen that the period and phase I duration of the integrated EMG in the intestinal interdigestive period are shortened and the phase II duration is prolonged. It shows that Fructus Aurantii Immaturus can enhance the tension and phase contraction of small intestinal smooth muscle.
4. Effect on uterine smooth muscle
The decoction of Fructus Aurantii Immaturus has obvious exciting effect on isolated uterus, eutopic uterus and uterine flaccidity of non-pregnant and pregnant rabbits, and can increase the uterine contraction rhythm. However, it can inhibit the pregnant or non-pregnant part of mouse uterus in vitro. Fructus Aurantii-Chinese herbal medicine
Anti-allergic effect
The hot water-soluble freeze-dried extract of Fructus Aurantii Immaturus was used in the passive skin allergic reaction (PCA) test in rats, and 100-3200mg/kg was injected intravenously, which had obvious inhibitory ability. In vitro test also showed strong anti-allergic activity to histamine release from rat peritoneal mast cells, and its main effective components were citrine, citrus flavonoids and 3,5,6,7,8,3', 4'- heptamethoxyflavone. Bitter in nature; Acid; Slightly cold meridian tropism: lung; Spleen; Liver; Stomach; Indications of large intestine meridian function: fullness of thoracic septum; Hypochondriac swelling and pain; Lack of food accumulation; Abdominal distension and fullness; Severe diarrhea; Rectum; Uterine prolapse. Spleen and stomach weakness and pregnant women should take it carefully.