both p>1％% calcium gluconate and vitamin c have different degrees of antiallergic and capillary permeability reduction effects. chlorpheniramine is a necessary drug for antiallergic and a reliable drug for treating allergy. The combination of the above drugs is suitable for patients with more rashes, severe itching or fever. Urticaria, commonly known as "rash", "wind pimple" and "wind bag", is a common allergic skin disease called "addiction rash" in Chinese medicine. When the body is in a sensitive state, many factors can induce urticaria, such as eating animal food such as fish, shrimp and crab, touching plants such as pollen and sumac, and using drugs such as penicillin, streptomycin, sulfonamides and serum, which are stimulated by cold, heat, wind and sunlight. In addition, gastrointestinal dysfunction, metabolic disorders and mental factors can also cause this disease. The onset of the disease is often urgent. When the human body is exposed to allergens, bright red, reddish or porcelain white wind masses with different sizes will appear in unspecified parts of the body, and sometimes blisters can appear on the surface of the wind masses, which can be dispersed and arranged, and can merge with each other to form irregular shapes such as rings and topographic maps. Wind masses often spread all over the body, but they can also be limited. This kind of wind mass often appears suddenly, and generally disappears quickly within 24 hours, leaving no trace after disappearing. However, new wind masses occur one after another, sometimes repeatedly many times a day, and the skin is severely itchy and has a burning or tingling sensation when it erupts. Serious patients may be mixed with palpitation, irritability, nausea, vomiting, and even lower blood pressure, resulting in anaphylactic shock symptoms. Nausea, vomiting, diarrhea and abdominal pain may occur when the digestive tract is involved; Involvement of the larynx and bronchus can lead to laryngeal edema, choking sensation, shortness of breath, chest tightness, dyspnea and even suffocation. According to the different course of disease, it can be divided into acute and chronic types, and those who can recover in a short period of time (from a few days to 1-2 weeks) are called a acute urticaria; If it recurs for several months (January-February) or even years, it is called chronic urticaria. Chronic patients generally have mild systemic symptoms, with frequent wheezes, some of which are timely, such as getting worse in the morning or before going to bed, while others are irregular.