No, it’s poisonous. The recipe is in the back part of the information.
The fruit contains 1.3% volatile oil, the main components of which are pinene (l-Pine-ne), camphene (l-Camphene), Bornyl isovale-rate, and Isoborneol. Also contains methoxyparsley (Ostho-le), Cnidimine (Edultin), IsoPiBrpinelline, Bergamot lactone, Dihydroo-roselol (Columbianetin) And its angelic acid ester (ColuInbianadin), acetate (o-Acetyl columbianetin); oral isovalerate, cnidiadiu (Cnidiadiu), isobutyryloxydihydrochenyl acetate. The roots contain cnidium, isosaxifrage, alloimperatorine, xanthotoxol, and imperatorine. The fruit contains about 1.3% volatile oil, the main components of which are 1-pinene (l-pinene), 1-camphene (l-camphene), bornylisovalerare and 7-methoxyparsleyol (osthole) )wait. In addition to 7-methoxyparsleyol, palmitic acid, β-sitosterol, bergapten, isopimpinellin and xanthotoxol, etc. According to reports, Chinese commercial Cnidoma monnieri fruits contain 0.20% of columbianadin, archangelicin, edultin, bergamotolide, isosaxifragein, and O-acetyl dihydroparanthin. (O-acetyl-columbianetin), dihydro-columbianetin, O-isvaleryl-columbianetin (O-islvaleryl-columbianetin), 3'-isobutyryloxy-O-acetyldihydro-columbianetin (3 '-isobutyloxy-O-acetylcolumbianetin) and O-isobutyldihydroacetin (O-isobutylcolumbianetin, cnidiadin). The seeds contain citrus lactone, orosclol and edible angelica.
1. Anti-pathogenic microorganism effect: Cnidium monnieri has inhibitory effects on Epidermophyton floccosum, Microsporum gypsum, and Microsporum woolly in vitro. Newcastle virus cultured in chicken embryos can extend the life of chicken embryos by 6 hours. Cnidium monnieri extract (1:2) has a strong killing effect on Trichomonas vaginalis in vitro. However, there are also reports that using liver extract as the culture medium, 10% and 20% Cnidium monnieri decoctions have no killing effect or very weak effect on Trichomonas vaginalis.
2. Sex hormone-like effects: Continuous subcutaneous injection of Cnidoma monnieri ethanol extract into mice for 32 days can prolong the estrous period, shorten the interestrus period, and cause estrus in castrated mice. The weight of the ovaries and uterus increases. The method of increasing the weight of the prostate, seminal vesicles, and levator ani muscles (mice) proved that Cnidium monnieri extract has androgen-like effects. It has no corrosive effect on rabbit vaginal mucosa.
3. Killing effect on sperm: Mix Cnidium monnieri extract powder with physiological saline into a suspension of 20%, 25%, 30%, 35% and 40%, and place it at room temperature for 48 hours, centrifuge at 200 rpm for 10 minutes, filter the supernatant, and store at 4°C. Use the medicine to observe the spermicidal effect. It can be seen that the spermicidal effect increases with the increase of the concentration of the medicine. The minimum effective concentration to inhibit human sperm within 20 seconds is 30%. Each milliliter of semen is mixed with different doses of Cnidoma monnieri extract powder. The lowest effective dose for inhibiting sperm motility is 250 to 300 mg. Experiments have shown that Cnidium monnieri may become a vaginal contraceptive.
Sex hormone-like effects
Cnidium monnieri ethanol extract, subcutaneously injected into mice every day for 32 consecutive days, can prolong the estrous period, shorten the interestrus period, and can cause the appearance of estrus in castrated mice. During estrus, the weight of the ovaries and uterus increases, and they have sex hormone-like effects. The method of increasing the weight of the prostate, seminal vesicles, and levator ani muscles (mice) proves that Cnidium monnieri extract has androgen-like effects and has no corrosion to the vaginal mucosa of rabbits. effect.
Other effects
In recent years, more research has been done on Cnidoma monnieri, and more and more pharmacological effects have been discovered.
4.1 Antifungal effect: In vitro tests of osthole, bergamot lactone and isosaxifrage have strong activity against Trichophyton mentagrophytes; Fungal effects.
4.2 Anti-arrhythmic: The aqueous extract of Cnidium monnieri has good effects on chloroform-induced ventricular fibrillation in mice, calcium chloride-induced ventricular fibrillation in rats and ornithine-induced arrhythmia in rats. It has a preventive effect and has an obvious therapeutic effect on the latter.
4.3 Local anesthesia: The aqueous extract of Cnidium monnieri has a blocking anesthesia effect on the isolated sciatic nerve of toads; it has an infiltration anesthesia effect on guinea pigs, and can be enhanced by epinephrine hydrochloride; on rabbits It has a spinal anesthesia effect, but has no surface anesthesia effect on the cornea of ??rabbits. It can also significantly prolong the sleep-inducing time of sodium pentobarbital.
4.4 Anti-allergic reaction: osthole can strongly inhibit passive skin allergic reactions in mice, has a protective effect on overall guinea pig histamine wheezing, and has a protective effect on the isolated ileum of guinea pigs caused by slow-reacting substances. It showed obvious antagonistic and blocking effects on the contraction and Schultz-Dzle reaction of isolated guinea pig ileum, and could inhibit the degranulation of rat peritoneal mast cells. The above effects are all in a certain dose-dependent relationship.
4.5 Anti-mutagenicity: Cnidium monnieri aqueous extract has been tested through Ames, sister chromatid exchange in isolated cells and chromosomal aberrations in living mouse bone marrow cells and polychromatic erythrocyte micronuclei tests. The drug has a strong anti-mutagenic effect.
4.6 Insecticide: Put Cnidium monnieri into sewage to kill larvae.
Gynecology
Treatment of trichomonas vaginitis
First rinse the vagina with 500ml of 10% Cnidium monnieri decoction, and then put 0.5 g of Cnidoma monnieri into the vagina for use Tablets (made from extract of Cnidium monnieri) 2 tablets. Continuous treatment for 5-7 days constitutes a course of treatment. Nearly a hundred cases have been observed, and most of them can be cured after one course of treatment. Trichomonas turn negative and the itching disappears; the vagina is clean and leucorrhea disappears or is significantly reduced. In addition, it has been tried on non-trichomoniasis vaginitis and can also reduce the secretion of leucorrhea. For those with cervical erosion, no adverse reactions are seen after application.
Dermatology
Treatment of acute exudative skin disease
Take 2 taels of Cnidium monnieri, wrap it with gauze, add 1500ml of water, boil for half an hour; After the pad is soaked, twist it half dry, apply it warmly to the area, and cover it with oil paper or plastic cloth to maintain a certain temperature and humidity, which can generally be maintained for 0.5 to 1 hour. Take it 4-6 times a day. 380 cases were clinically observed. Most of them were treated for 5-10 days, and the exudates were significantly reduced and the inflammation subsided. No side effects were found. You can also grind the Cnidium into fine powder, mix it into an ointment with Vaseline, and apply it to the affected area, 1-2 times a day. Observed 15 cases of infant eczema (erosive stage), most of them began to reduce the exudation on the second day of medication, and then scabbed and healed.
Efficacy
Warming the kidneys and strengthening yang; drying dampness and killing insects; dispelling wind and relieving itching
Medicine contraindications
If there is dampness and heat in the lower burner, or the kidneys Those with insufficient yin, easily moved fire, and weak Jing Guan should not take it.
1. "Compendium of Materia Medica": Peony, Croton, Fritillaria.
2. "Compendium of Materia Medica": Do not take it if there is fire in the kidneys or heat in the lower part.
3. "Ben Jing Feng Yuan": Do not take it if the kidney fire is easy to move and the yang is strong and the essence is not solid.
Effect classification: Warming medicine
Processing
Pick out impurities, sieve to remove mud, wash and dry in the sun.
1． "Lei Gong Pao Zhi Lun": When making snake bed, you must use thick blue juice and natural juice of Baibucao root. When the two flavors are soaked together in Sanfu, drain out the sun dried juice, then mix it with raw rehmannia glutinosa juice and steam it. From noon to Hai, Sun Use dry.
2. "Rihuazi Materia Medica": Snake bed, if taken with medicine, remove the skin and take the kernels, stir-fry slightly to kill poison, it is not spicy, make soup to cleanse the disease, and it will make the disease.
Textual research
From "Shen Nong's Materia Medica".
1． "Famous Doctors": Cnidium monnieri grows in Linzi Chuan Valley and fields. May fruits, dried in the shade.
2. Tao Hongjing: There are many snake beds in the fields and villages near the road. The flowers and leaves are like wild grass.
3． "Shu Materia Medica": "Illustrated Book" says that the snake bed is like small leaves of Ligusticum rhizome, with white flowers and seeds like millet grains, yellow and white. Wetlands were born, and they are everywhere today. Those who left Yangzhou and Xiangzhou were good, and the seeds were collected and dried up.
4． "Compendium of Materia Medica": Cnidium monnieri, born in March, seedlings three to two feet high, with green leaves broken into clusters like wormwood branches, with more than a hundred flower heads on each branch, forming the same nest, like horse celery, blooming in April and May White flowers, like scattered water seeds, yellowish brown, like millet, to light and weak.
5. "Outline": Snake bed, snakes and snakes lie under it, so it has names such as snake bed and snake millet. Its flowers are clustered like broken rice, and its seeds are composed of two pieces, which are thin like dill seeds and also have fine edges. Any flowers that actually look like snake beds include Angelica sinensis, Ligusticum rhizome, cress, Ligusticum root, and carrot.
Family and genus classification
Apiaceae
Latin name
Fructus Cnidii
Indications
Men’s impotence; wet and itchy scrotum; women’s uterus cold and infertile; cold and damp vaginal discharge; vaginal itching and swelling and pain; rheumatic arthralgia; eczema and scabies
Treatment of impotence
Divide dodder, cnidium, and schisandra into equal parts. The top three flavors, the bottom one, honey pills like Wuzi. Drink and take thirty pills, three times a day. ("Qianjin Prescription") This is a commonly used adjuvant drug in the treatment of impotence. Nearly half of the more than 30 impotence prescriptions in Qianjin Prescription use Cnidium monnieri
Treat women's yin-cold
Warmth Medicine for sitting in the Yin: Cnidium monnieri, powdered, mixed with a little white powder, as big as a jujube, wrapped in a cotton ball, it will be naturally warm. ("Golden Chamber Synopsis" Cnidium monnieri powder)
Treat women's vaginal itching
50 grams of Cnidium monnieri and 10 grams of alumen. Decoction and wash frequently. ("Binhu Collection of Simple Prescriptions")
Cure postpartum vaginal prolapse
One liter of Cnidium monnieri, wrapped in cloth and ironed, can also treat postpartum vaginal pain.
("A Thousand Golden Prescriptions")
Treatment of protruding internal organs in women
One liter of Cnidium monnieri and twenty-seven pieces of plum blossoms. Five liters of water, boil two and a half liters, wash it, and wait for ten days to pass. ("Seng Shen Ji Prescription" Cnidium Washing Prescription)
Treatment of trichomonas vaginitis
1. 25 grams of Cnidium monnieri, decoct in water and lavage the vagina. (Jiangxi "Herbal Medicine Handbook")
2. 50 grams of Cnidium monnieri and 15 grams of Cortex Phellodendron. Suppositories (2 g in weight) are made with glycerin gelatin as the base, and one piece is placed intravaginally every day. (Inner Mongolia's "Selected Materials on New Chinese Herbal Medicine Treatment Methods")
Treatment of scrotal eczema
Take 25 grams of Cnidium monnieri, boil it in water and wash the vagina. (Jiangxi "Handbook of Herbal Medicine")
Treatment of malignant sores in children
1.5 grams of glutinous rice powder, 0.5 grams of Coptis chinensis (to remove beards), and 1.5 grams of Cnidium monnieri. Pound the medicine into powder. Every time, wash the sore with warm salt soup, wipe it dry, and apply oil on it. ("Sheng Hui Fang")
Treat lip sores in children
Also treat ear sores, head sores, and fistula sores: 50 grams of alumen (burnt ash), 50 grams of Cnidoma monnieri gram. For the end, mix it dry and put it on the sores. ("Micro Prescriptions for Pediatric Health")
Treatment of eczema
Atopic dermatitis, sumac allergy, tinea pedis: Cnidium monnieri, eucalyptus leaves, neem bark, duck's foot wood, Sophora flavescens and Kochia kochia are taken in appropriate amounts, boiled in water and soaked in water to wash the affected area twice a day. (Jiangxi "Handbook of Herbal Medicine")
Treatment of sore throat in winter
Those who cannot prescribe the medicine: burn Cnidium monnieri in a bottle, put the mouth of the bottle in your mouth and smoke, the phlegm will come out spontaneously . ("Sheng Hui Fang")
Treatment of kidney deficiency and vaginal discharge
Use Cnidium monnieri alone as powder, add a little white flour, add water and mix well, make a pill as big as a jujube, wrap it in cotton wool and put it into the vagina middle.
Treat peripheral neuritis
6 grams each of Cnidium monnieri, Kochia Fructus, Cortex Phellodendron, Myrrh, and Sophora flavescens. After decoction, soak the affected area in moderate heat, take 1 dose per day.
Usage and dosage of Cnidium monnieri: Oral administration: decoction, 3-9g; or taken into pills or powders. External use: appropriate amount, decoction for fumigation and washing; or make into medicine or suppository; or grind into fine powder for application.
Contraindications for the use of Cnidium monnieri: Those with dampness and heat in the lower burner, insufficient kidney yin, easy movement of phase fire, and unstable Jing Guan should not take Cnidoma monnieri.
Cnidium monnieri soup
Effects: clearing away heat and drying dampness, dispelling wind and relieving itching. It is used to treat kidney cyst wind, dryness and extreme itching. People like to bathe in hot soups, and even develop pimples, which are shaped like red millet, numb and itchy, scratched and soaked with fat and water, and the skin is hot and painful like fire.
Prescription: 15 grams each of clematis, cnidium monnieri, and angelica tail, 9 grams of shrunken sand shell, 15 grams each of rhubarb and sophora flavescens, and 7 onions.
Usage: Take 1 liter of water, boil for several times, pour into a basin, smoke first, then soak in warm water.
Excerpt: Volume 69 of "Yizong Jinjian"
Cnidium monnieri and sophora flavescens wine
Efficacy: remove dampness, detoxify, relieve itching. Suitable for neurodermatitis, itchy skin, chronic eczema, ringworm, etc.
Recipe: 25 grams of Cnidium monnieri, 25 grams of Sophora flavescens, 12 grams of Fangfeng, 12 grams of fresh white peel, 12 grams of alum, 10 grams of Sichuan pepper, 1 pound of 50% white wine (or 75% alcohol).
Preparation method: Process the above-mentioned medicines into fine powder, put them in gauze bags, seal them with wine and soak them for 30 days, and shake them frequently. Just remove the medicine bag.
Dosage: external use. 3-4 times a day, use absorbent cotton balls dipped in medicinal wine to rub the affected area externally.
Note: This wine is for external use and must not be taken internally. If 3 grams of Acanthus chinensis, 5 grams of Trichosanthes chinensis seeds, and 15 grams of Hibiscus bark are added to the recipe, the effect will be better.
Cnidium Monnieri Baibu Powder
Efficacy: clearing away heat and promoting dampness, detoxifying and stopping vaginal discharge.
Prescription: 15g each of Atractylodes, Rhizoma Rhizoma, Cnidii Monnieri, Phellodendron, Sophora flavescens, Forsythia suspensa, 10g Schizonepeta, 5g alum, and 15g Hibiscus bark.
Usage: Decoction the medicine into 250ml liquid, and do vaginal washing for married women, 1 dose per day, and every 6 times is a course of treatment. The patient takes the lithotomy position, uses a speculum to expose the cervix, and first wipes the vagina dry with a cotton ball soaked in medicinal solution or a dry cotton ball. In severe cases, in addition to flushing, the patient is also asked to soak himself to enhance the curative effect. If conditions permit, you can rinse twice a day for better results.
Note: All kinds of vaginitis and cervicitis are characterized by excessive vaginal discharge and vaginal itching. From a modern medical point of view, a considerable number of cases are caused by infection with trichomonas, fungi and cervical inflammation. Therefore, during treatment, in addition to oral Chinese medicine for syndrome differentiation and treatment, topical medication must be used directly to the hospital to achieve significant results. Moreover, the method is simple, economical and easy to implement, and the course of treatment is also short, so it is easy to be widely used.
Cnidium monnieri and Sophora flavescens powder
Effects: clearing heat and drying dampness, killing insects and relieving itching, detoxifying and relieving pain, antiseptic and reducing swelling.
Recipe: 30g each of Sophora flavescens, Cnidium monnieri, Coptis chinensis and Cortex Phellodendron, 10g each of Sichuan peppercorns and alum, and 3g of borneol. ***Prepared for fine powder disinfection.
Usage: Before each application of medicine, wash the vulva and vagina with 3% baking soda solution or 1:1000 chlormethionine. After applying medicine, change into clean underwear, 1-2 times a day, 5 times is 1 Treatment course.
Note: Sophora flavescens powder is an effective prescription that has been clinically explored to treat fungal vaginitis. In the prescription, Sophora flavescens and Cnidium monnieri are mainly used to clear away heat and dampness, kill insects and relieve itching; supplemented with Coptis chinensis, Cortex Phellodendri, and Sichuan peppercorns, they can not only strengthen the effect of detoxifying and drying dampness, but also promote the rapid absorption of vaginal mucosal edema; and withered alum, Borneol can reduce sores and dry out dampness, and has a particularly effective effect on reducing swelling and relieving pain.
The above-mentioned drugs have extensive antibacterial and fungal inhibitory effects, so they are indeed miraculous in treating fungal vaginitis.
[4]