Alias sulfur bitter; Diarrhea salt, magnesium sulfate mbth indications 1. It can be used for constipation and abnormal intestinal fermentation, and can also be used in combination with anthelmintics. Combined with activated carbon, it can treat food or drug poisoning. 2. Used for obstructive jaundice and chronic cholecystitis. 3. Used for convulsion, eclampsia, uremia, tetanus, hypertensive encephalopathy and acute renal hypertensive crisis. 4. It is also used for patients with frequent angina pectoris and poor therapeutic effect, especially for patients with hypertension. 5. External hot compress, anti-inflammatory and detumescence. Dosage and usage: 1. Catharsis: Take 5 ~ 20g orally each time, usually on an empty stomach in the morning, and drink 100 ~ 400 ml of water at the same time, or take it after dissolving it in water. 2. cholagogic: 2 ~ 5g each time, 3 times a day 1, taken before meals or between meals. You can also take 33% solution, each time 10ml. 3. Anticonvulsion, lowering blood pressure, etc. : intramuscular injection of 25% solution, 4 ~10 ml each time; Or use 5% ~ 10% glucose injection to dilute the 25% solution of10 ml to the concentration of 1% or 5% and then drip intravenously; For angina pectoris, 10% solution 10ml can be diluted with 5% ~ 10% glucose injection 10ml and then slowly injected intravenously, once a day, for 1 0 days. Precautions 1. If a large amount of solution with high concentration is ingested during catharsis, a large amount of water may be absorbed from the tissue, leading to dehydration. 2. Because intravenous injection is dangerous, it should be used by experienced doctors, and the injection should be slow, and pay attention to the patient's breathing and blood pressure. If poisoning (such as respiratory muscle paralysis, etc.) occurs. ), 10% calcium gluconate injection 10ml can be used for rescue. 3. Patients with intestinal bleeding, patients with acute abdomen, pregnant women and menstruating women are forbidden to use this product for catharsis. 4. Patients poisoned by central depressants (such as phenobarbital) should not use this product to induce diarrhea, so as not to aggravate central depression. Specification injection: 1g( 10ml) and 2.5g (10ml) each. White mixture: 30g magnesium sulfate and 5g light magnesium carbonate.

Pharmacological action:

Injection can dilate blood vessels, lower blood pressure, inhibit the central nervous system, have the functions of sedation, spasmolysis and relaxation of skeletal muscle, reduce intracranial pressure, and make ventricular muscle repolarization tend to be consistent. Oral administration can increase intestinal osmotic pressure, keep a large amount of water in the intestine, stimulate the intestinal wall and play a laxative role. About 4~6 hours after taking the medicine, liquid feces will be discharged, and the sphincter of biliary tract will relax, causing gallbladder emptying. External application has detumescence effect.

Dosage of dosage form:

Injection: 1 0ml:1g,10ml: 2.5g, solution: 50%.

Functional purpose:

Injection can be used for eclampsia, hypertensive crisis and magnesium deficiency, and can also be used for apical reversible ventricular tachycardia, especially for hypertension and ventricular agitation, but not for isoproterenol and electrical stimulation pacing. Oral administration can be used for constipation, catharsis and cholagogue. External use can be used for contusion, cellulitis, erysipelas, etc. Local wet compress after heating.

Usage and dosage:

Oral. Adult dosage: laxatives: 5~20g each time, taken on an empty stomach in the morning; Cholagogic: 2~5g each time, 3 times a day. Child dose: per year1g. Local warm after local wet compress. Intramuscular injection or intravenous drip. Adult dosage: 1~2.5g each time, diluted to 10%GS for intravenous drip, slowly drip, with the dropping rate per minute.

Adverse reactions:

Too fast dripping speed and too large dosage can cause flushing, tendon reflex disappearance, cardiac arrest, respiratory depression, blood pressure drop and so on.

To disable or use with caution:

Pregnant women (except eclampsia), menstrual women, patients with intestinal bleeding, acute abdomen, severe renal insufficiency and heart block are prohibited.

Precautions:

1. For static infusion, half of them are infused within 15~20min, and the other half within 90min. Blood pressure, pulse, respiration and knee reflex were observed every 15 minutes, and 1 0% glucose calcium or 5% calcium chloride was prepared for rescue. 2. Intravenous injection is dangerous and generally not used. People who use digitalis should pay special attention to the existence of arrhythmia. When taken orally, it should be diluted with plenty of water before use. 4, intramuscular injection can cause local pain.