Appendicitis is the most common surgical disease. It is estimated that 15 people suffer from acute appendicitis in their lifetime. From 65438 to 0886, American Fitz was correctly named appendicitis. The typical clinical manifestation of acute appendicitis is gradually dull pain in the upper abdomen or around the umbilicus, and abdominal pain transfers to the right lower abdomen after several hours. Often accompanied by loss of appetite, nausea and vomiting. At the initial stage of onset, there were no obvious systemic symptoms except low fever and fatigue. If acute appendicitis is not treated early, it can develop into gangrene and perforation of the appendix, complicated with localized or diffuse peritonitis. The mortality rate of acute appendicitis is below 1%, and the mortality rate after diffuse peritonitis is 5 ~ 10%. After non-surgical treatment or self-healing, acute appendicitis can leave fibrous tissue hyperplasia, appendix wall thickening, lumen stenosis and surrounding adhesion, which is called chronic appendicitis and easily leads to another acute attack. The more attacks, the more serious the damage of chronic inflammation, which can be repeated acute attacks, asymptomatic or occasionally mild pain in the right lower abdomen, so it is also called chronic recurrent appendicitis. If the patient has never had a history of acute appendicitis, but complains of chronic lower right abdominal pain, it is not easy to diagnose chronic appendicitis and remove the appendix. Attention should be paid to excluding other ileocecal diseases, such as tumor, tuberculosis, nonspecific appendicitis, Crohn's disease and mobile appendicitis, as well as mental and neurological factors, otherwise appendectomy is difficult, and even if there are no other diseases, the symptoms may not be eliminated.

One end of the appendix communicates with the cecum, which is about 6 ~ 8 cm long, and the lumen is narrow, only about 0.5cm. There are abundant lymphoid tissues in the appendix wall, which constitutes the anatomical basis of the appendix's easy inflammation. This anatomical feature is also easy to cause obstruction of the appendix. About 70% of patients can find that the appendix cavity is obstructed by different reasons, such as obstruction, fecal stones (that is, feces that stay for a long time are mixed and coagulated with appendix secretions, which may be deposited by minerals such as calcium), crop residues, twisted appendix itself and parasites (such as roundworms and pinworms). After the inflammation of acute appendicitis subsides, scar stenosis can be formed in the appendix, which is easy to lead to the recurrence of inflammation. Due to the abundant lymphatic tissue in the appendix wall and serious inflammatory reaction, the occurrence of obstruction is further promoted. Usually there are a lot of intestinal bacteria in the appendix cavity. When there is obstruction, the pressure in the lumen at the distal end of the obstruction increases, the blood circulation of the appendix wall is affected, and the damage of mucosa creates conditions for bacterial invasion. Sometimes, although feces, food residues, parasites and foreign bodies in the appendix cavity will not cause obstruction, they can cause mechanical damage to the appendix mucosa and facilitate the invasion of bacteria. In addition, gastrointestinal dysfunction will also make the muscles of the appendix wall spasm, affect the emptying of the appendix and even affect the blood circulation of the appendix wall, which is also the cause of inflammation. Bacteria can invade the appendix through blood circulation and cause inflammation, which belongs to blood-borne infection.