(2) Amoeba enteritis. When the lesion evolves into a chronic stage, granulation tissue hyperplasia at the base of the ulcer and proliferation of surrounding fibers make the intestinal wall thicken and the intestinal cavity narrow, which is easy to be misdiagnosed as cancer. At this time, biopsy is necessary.
(3) Intestinal tuberculosis. The onset age is relatively young, and there is a history of tuberculosis in other organs in the past, which is easy to occur in ileocecum. However, due to a large number of tuberculous granulomas and fibrous tissue hyperplasia of proliferative intestinal tuberculosis, the intestinal wall becomes thick and hard, which is easily confused with colorectal cancer. Pathological biopsy is needed to make a definite diagnosis. X-ray barium meal examination can find irritation or jumping at the focus, which is helpful for diagnosis.
(4) Localized enteritis. It is common in young people, with symptoms and signs such as abdominal pain, diarrhea, fever, emaciation, anemia, anorexia, nausea, vomiting, abdominal mass and fistula formation, which can be distinguished by X-ray barium meal and fibercolonoscopy.
(5) Chronic bacillary dysentery. The patient may present with abdominal pain, diarrhea, rare purulent bloody stools, mild internal urgency and then severe. After stool culture, barium enema and endoscopy, it is not difficult to make a diagnosis.
(6) Ulcerative colitis. Symptoms are similar to chronic bacillary dysentery, but there is a history of recurrent episodes, and stool culture is negative. Microscopic examination of sigmoid colon shows that the mucosa is fine granular, the vascular texture disappears, accompanied by erythematous congestion and oval small ulcers, and its surface is often covered with yellow-white exudate, and in severe cases there are large irregular ulcers.
(7) others. Such as willow lymphogranuloma, rectal endometriosis, colonic diverticulitis, etc., can be differentiated by symptoms, signs, X-ray examination and fiberoptic colonoscopy.