Many patients for their own sudden occurrence of myocardial infarction and feel confused, they think that they can usually eat, drink, and can jump, without any discomfort, how can happen so They think that they can usually eat, drink and dance without any discomfort, how could such a serious coronary heart disease occur? In fact, as long as they make a detailed examination, we can find that many of them have high blood lipids, and hyperlipidemia is currently recognized by the medical profession as one of the most important causes of coronary heart disease.
We should be clear that the damage caused by hyperlipidemia is a slow, gradual and insidious process. Hyperlipidemia itself has no obvious symptoms, and it is difficult to be detected without blood lipid tests. If a hyperlipidemic person has high blood pressure or smokes at the same time, it will accelerate the process of atherosclerosis and lead to narrowing and blockage of blood vessels. At this time, patients may have dizziness, chest tightness, and in severe cases, sudden stroke, myocardial infarction, or even cardiac death. Because hyperlipidemia is gradually devouring the life, people figuratively call it "invisible killer".
So, in the busy work and life, when you often appear dizziness, forgetfulness, physical decline, sleep disturbance, chest tightness and shortness of breath, etc., you must pay attention to their own blood lipid status. Doctors suggest that middle-aged and elderly people should have their blood lipids checked every six months or once a year in order to keep abreast of and adjust their blood lipid status. Focusing on developing a healthy lifestyle can prevent hyperlipidemia, the "invisible killer," from attacking you and help you stay away from this killer.
Controlling weight, eating a light diet, reducing salt, fat and sugar intake, quitting smoking and alcohol, learning to cope with physical and mental stress, maintaining a good state of mind, and especially adhering to sports, which can enhance cardiovascular and cerebral vascular function, improve immunity, regulate emotions, and help to reduce body weight and prevent obesity, are all effective measures to prevent hyperlipidemia.
2, why patients with coronary heart disease have to check lipids
Coronary heart disease patients in the hospital, the doctor will recommend a lipid test, this is because of the following reasons:
(1) Dyslipidemia is one of the main pathogenic risk factors for coronary heart disease. Currently recognized as the main risk factors for coronary heart disease are: dyslipidemia, hypertension, diabetes mellitus, smoking, etc., of which dyslipidemia coronary heart disease is the most important pathogenic risk factors. Many large-scale clinical trials have confirmed that lipid-lowering therapy for patients with coronary heart disease can reduce the incidence of heart disease and mortality.
(2) Checking blood lipids is helpful in guiding the treatment of patients with coronary heart disease. At present, lipid-lowering treatment is one of the important and effective measures in the treatment of coronary heart disease, but the treatment of each patient is not uniform, and different treatment programs should be selected according to the degree and type of dyslipidemia of the patient. Through the lipid test, we can understand whether the patient has dyslipidemia and the degree and type of dyslipidemia, which is helpful to guide the patient's treatment.
(3) Lipid-lowering treatment for patients with coronary heart disease must be "up to standard". In order to achieve good therapeutic effects, lipid-lowering therapy for patients with coronary artery disease must reach a certain target value, and in particular, low-density lipoprotein cholesterol (LDL-C) should be lowered to less than 2.6 mmol/liter.
This shows that lipid screening is necessary in patients with coronary artery disease.
3, high blood fat and high blood pressure
We often see part of the high blood fat patients at the same time have high blood pressure, medical experts also regard high blood fat and high blood pressure is a sister disease, thus causing people to think of high blood fat can cause high blood pressure.
A large number of medical studies have shown that there is indeed a close relationship between blood lipid levels and blood pressure. A study of 16,525 healthy men found that after the age of 40, diastolic blood pressure (i.e., low blood pressure) exceeded 110 mm Hg, compared with diastolic blood pressure of less than 70 mm Hg, blood cholesterol values on average increased by 0.71 mmol / liter. This is because elevated lipids impede vasorelaxation, which results in vasoconstriction. Therefore, patients with high lipids are often accompanied by hypertension.
Since high blood lipids may be a risk factor for hypertension, lowering blood lipids should also lower blood pressure in hypertensive patients. Therefore, it is now advocated that if a hypertensive patient has high blood pressure at the same time, in addition to actively lowering blood pressure, should be early with lipid-lowering treatment. Because lowering blood pressure and lowering lipids at the same time, not only can make the blood pressure easy to fall to normal, more conducive to the prevention of coronary heart disease and cerebral stroke.
If a hypertensive patient's blood lipids are normal, should he or she be treated with lipid-lowering therapy at the same time? Some people have observed hypertensive patients with normal blood lipids and found that active lipid-lowering treatment can significantly reduce the degree of atherosclerosis, improve the elasticity of blood vessels, and make hypertension easier to control. It also helps to prevent atherosclerosis from causing serious diseases such as coronary heart disease and stroke. Therefore, lowering blood pressure should also control blood lipids, which is also in line with the basic principles of cardiovascular disease prevention and treatment.
4, high blood lipid and diabetes
We see many patients with high blood lipid often combined with diabetes, which makes people think, high blood lipid can cause diabetes? The latest research results show that some patients in the diagnosis of diabetes mellitus before the existence of elevated blood lipids, it is presumed that elevated blood lipids can produce lipotoxicity, damage to the pancreas secretion of insulin function or make the role of insulin weakened. And insulin is crucial to the body's glucose metabolism. Reduced insulin secretion or its role is weakened, it will develop and diabetes, of course, diabetes can also cause elevated blood lipids. When high blood fat and diabetes at the same time, it is often difficult to distinguish who is the cause and who is the fruit. Therefore, recently some people call diabetes for sugar lipid disease.
5, high blood lipids and stroke
Stroke, also known as stroke or cerebrovascular accident, is a group of common diseases in the elderly, frequent disease, great harm. Stroke includes two conditions: cerebral infarction and cerebral hemorrhage.
Cerebral infarction, also known as ischemic stroke, refers to the brain blood supply obstacle, ischemia, lack of oxygen caused by necrosis and softening of brain tissue, causing neurological dysfunction. A large number of studies have confirmed that there is a clear correlation between cerebral infarction with atherosclerosis as the underlying lesion and elevated serum cholesterol. Hereditary disorders of lipid metabolism, such as familial hypercholesterolemia, are also important causes of ischemic stroke. High triglycerides (TG) are strongly associated with cerebrovascular disease, and the risk of ischemic stroke increases with elevated plasma triglyceride concentrations. In contrast, elevated high-density lipoprotein cholesterol (HDL-C) helps prevent ischemic stroke.
Cerebral hemorrhage, which is bleeding caused when a cerebral blood vessel ruptures, is also a common cerebrovascular disease in China. The coexistence of hypertension and atherosclerosis is the most common cause of cerebral hemorrhage. Cerebral hemorrhage is also closely related to dyslipidemia.
Therefore, elevated blood lipids are a major risk factor for stroke, and cerebral atherosclerosis caused by high blood lipids is an important basis for the occurrence of stroke. Many studies have confirmed that active lipid-lowering treatment can prevent the occurrence of stroke.
6, blood triglyceride elevation why will cause acute pancreatitis
Acute pancreatitis is a serious gastrointestinal disease, the heavy can cause pancreatic necrosis lead to the patient's rapid death. The etiology of acute pancreatitis is not well understood, and in some patients it is likely to be associated with markedly elevated blood triglycerides (more than 4 mmol/liter). As mentioned earlier, celiac disease and very low-density lipoprotein (VLDL) are triglyceride-rich lipoproteins, and they are also the largest lipoproteins. The increase in celiac disease makes it easy to form emboli, which rapidly obstruct the blood flow in the microvessels of the pancreas, thus leading to acute pancreatitis; in addition, the fatty acids released by hydrolysis of excess celiac disease and VLDL, as well as the haemolysed lecithin released from pancreatic capillary beds, exceed the amount that can be bound by albumin. the amount of albumin that can be bound, and the pancreatic cell membrane is lysed, producing chemical pancreatitis. Hypertriglyceridemia predisposes to pancreatitis if overeating occurs, and is more likely to occur in patients with a history of pancreatitis. Many patients with high plasma triglyceride levels have intermittent epigastric pain, and serum amylase does not reach the level required to diagnose pancreatitis (this is especially true in those with a history of past episodes of pancreatitis), which may be an early manifestation of pancreatitis.
7, fatty liver and high blood fat
The so-called fatty liver is due to excessive deposition of fat (mainly triglycerides) in the liver, it is generally believed that the fat accumulation in the liver more than 5% of the weight of the liver, can be called fatty liver. When the amount of fat in the liver reaches 5% to 10% of the liver weight, it is mild fatty liver, if it reaches 10% to 25% of the liver weight, it is moderate fatty liver, and if it exceeds 25%, it is severe fatty liver.
At present, there are many reasons for the occurrence of fatty liver, the common ones are: simple obesity, malnutrition, diabetes, alcoholism, hyperlipidemia and so on. In addition, endocrine disorders, exposure to toxic chemicals, hormonal drugs, pregnancy, small bowel bypass surgery, long-term extra-gastrointestinal nutrition, tumor patients after chemotherapy and radiation therapy caused by radioactive hepatitis can cause fatty liver. In short, the occurrence of fatty liver is indeed related to hyperlipidemia, but there are quite a number of patients with fatty liver and blood fat is not elevated.
It is worth pointing out that now there are many people in the liver ultrasound, was diagnosed as "fatty liver", which makes the "fatty liver" seems to have become a "fashionable disease This makes "fatty liver" seem to become a "fashionable disease", causing people to doubt more and more, the reason for this is probably related to the diagnostic criteria for fatty liver is not consistent, and doctors are not rigorous enough to grasp the diagnostic criteria.
8, walking limp and high blood fat
People to old age, often complain of back of the ear, eyes, legs are not good. Visible leg inconvenience in the elderly is not uncommon, intermittent claudication is the main reason for the elderly leg inconvenience. Intermittent claudication refers to the pain in the calf and thigh muscles that occurs after walking a certain distance and must stop and then rest for a period of time before disappearing. The narrowing of the blood vessels in the legs is the cause of intermittent claudication, why does narrowing of the blood vessels in the legs lead to intermittent claudication?
When the blood vessels of the lower limbs are normal, the blood in the vessels increases after exercise, and therefore can meet the blood and oxygen needs during exercise. However, when there exists stenosis of the blood vessels of the legs, at first the blood in the vessels can still increase with the exercise, but after increasing to a certain extent, it will not continue to increase, therefore, when the amount of activity reaches a certain level, the muscles will be ischemia and hypoxia, resulting in ischemic-hypoxic pain. Atherosclerotic plaque on the blood vessel wall is the direct cause of blood vessel stenosis, there is a large amount of fat accumulation in this plaque, the nature of the plaque resembles thin rice, so it is called atherosclerotic plaque, atherosclerotic plaque surface by the fiber package, protruding from the lumen of the blood vessel, causing blood vessel stenosis, just like there is sediment silted up on the riverbed. However, the blood vessel wall itself cannot produce fat, and the fat in the plaque comes from the fat in the blood, just as the silt in the sprinkling bed comes from the flowing river. Lipids are mainly reflected in the fat content of the blood. The higher the lipids, the more fat is deposited on the blood vessel walls, and the higher the risk of atheromatous plaques and narrowing of blood vessels. Therefore, walking limp is also closely related to elevated blood lipids.
9, high blood fat will cause blood viscosity increased
Blood viscosity is affected by a number of factors, including the level of blood lipids is the main factor, whether triglycerides or cholesterol in the blood are in the form of lipoproteins exist. When the concentration of triglyceride increases, the large particles of lipoproteins such as chyme particles and very low density lipoproteins will increase, which will cause the friction and resistance of blood flow to increase, which is also manifested as an increase in blood viscosity. Similarly, if the concentration of cholesterol in the blood increases, the LDL particles in the blood will increase, which will also lead to an increase in blood viscosity. Clinically, the application of lipid-lowering drugs that can reduce blood lipids, can also reduce blood viscosity.