The key to the success of the experiment to determine the saponification reaction rate constant and its activation energy lies in experimental design, experimental equipment, use of appropriate methods, data processing, and four key factors:

1. Experimental design: Design an appropriate experimental plan and consider the control of various experimental conditions and parameters, such as substance concentration, temperature, reaction time, etc. Specifically, it is necessary to ensure that the temperature range selected for the experiment covers the starting temperature and ending temperature of the reaction, and since the saponification reaction rate is usually slow, the reaction time must be long enough.

2. Experimental instruments: Ensure the accuracy, precision and stability of experimental instruments, such as reactors, constant temperature water baths or furnaces, timers, etc.

3. Use appropriate methods: Generally, the saponification reaction rate constant and its activation energy can be determined by gravimetric method or conductivity method. These methods need to ensure the reliability of the measurement data, average the measurement results through multiple experiments, and perform statistical processing of the data.

4. Data processing: Data analysis and calculations are required, including the use of statistical software for data fitting and parameters required for solution. If the experimental data does not match the ideal data fitting results, it may be necessary to adjust the experimental design or choose a different data processing method.