Foods that are rich in nutrients or irritants are especially likely to induce certain diseases (especially old diseases) or aggravate existing diseases.

Fish, shrimp, crab itself contains histamine, and histamine can increase vascular permeability, microvascular dilatation, congestion, plasma exudate, edema, glandular hypersecretion and eosinophilic leukocytes increase, which led to the body metabolic reaction, that is, allergic reaction, triggered by skin diseases, such as erythema, pimples, blisters, fever.