1, inflammation
Inflammation affects the whole body, including blood vessels. More and more studies have proved that the degree of inflammatory reaction determines the stability of plaque and the incidence of cardiovascular events. It can directly infect vascular wall cells, damage vascular intima, reduce immunity and make bad cholesterol available. At this time, phagocytes combine with bad cholesterol to form "foam cells", which in turn attract some inflammatory cells and accelerate the development of the disease.
Therefore, inflammation sometimes increases the risk of cardiovascular disease. For example, patients with periodontal disease and influenza increase the risk of heart disease and stroke.
2. Hypoxia
When the human body lacks oxygen, the oxygen free radicals in the blood increase, which will directly stimulate the inflammatory reaction of the inner wall of blood vessels; The change of liver metabolism accelerates the inflammatory changes of vascular endothelium, which leads to the widening of the gap between vascular cells. At this time, blood lipids will penetrate under the inner wall of blood vessels through the widened vascular cell gap. After a long time, cholesterol crystals will also deposit on the inner wall of blood vessels, forming atherosclerosis. Especially snoring during sleep may also increase the risk of cardiovascular and cerebrovascular diseases, such as sudden death at night.
Step 3 smoke
Heavy smoking can lead to vascular endothelial cell damage and decrease blood oxygen concentration, thus blocking cholesterol and making platelets accumulate to form fat plaques. It can also cause the proliferation of vascular smooth muscle cells and accelerate the process of arteriosclerosis.
4. Hypertension
With the increase of blood pressure, the impact of blood flow on the wall of the tube will also increase, just as the flood hitting the dam is easy to cause damage, especially at the bifurcation of blood vessels, which is more likely to cause cholesterol and lipid deposition, thickening the wall of the tube, narrowing the lumen, and forming arteriosclerosis and stenosis. At this time, in order to make the blood flow smoothly, the body's blood pressure will rise further and may fall into a vicious circle. Hypertension promotes atherosclerosis, which mostly occurs in aorta and middle artery, including coronary artery of heart and cerebral artery of head. If blood pressure is not controlled, the incidence of myocardial infarction will increase by 2-3 times and the incidence of stroke will increase by 4 times.
5, hyperglycemia
When blood sugar is too high, lipoprotein will denature, and free fatty acids in the body will increase, which will be further converted into bad cholesterol and accumulated on the blood vessel wall. Moreover, the osmotic pressure of blood will increase, and the blood vessels will be in a hypertonic state, which will damage the vascular endothelium, just like pickles.
6, high uric acid
The harm of high uric acid is not just gout! Long-term hyperuricemia will stimulate the vascular wall, promote plaque formation, and also cause hyperlipidemia and hyperglycemia, further affecting the vascular environment. Therefore, hyperuricemia has become an important pathogenic factor such as angina pectoris, myocardial infarction and stroke.
7, hyperlipidemia
Hyperlipidemia will not only lead to lipid deposition in the blood under the vascular intima, but also stimulate inflammation and cause damage to the vascular intima. Hypertriglyceridemia and hypercholesterolemia are collectively referred to as hyperlipidemia, and they also have synergistic effects to further promote vascular diseases. Generally speaking, elevated triglycerides will not cause any symptoms, but it is a silent killer, and once symptoms appear, it will often be more serious. It is also an accomplice to bad cholesterol.
See if you have the above seven conditions, and you can find arteriosclerosis as soon as possible.