The best drug for treating hypertension is the first-line long-acting antihypertensive drug. Because the treatment of hypertension should be based on individualized treatment, that is to say, the best antihypertensive drug is suitable for you. For example, patients with hypertension, if accompanied by proteinuria, or impaired glucose tolerance, diabetes, heart failure, suggest that patients can use antihypertensive drugs, such as perindopril, enalapril, irbesartan, telmisartan, etc. It can not only lower blood pressure, but also prevent left ventricular remodeling. However, if hypertension patients are accompanied by renal insufficiency, such as creatinine greater than 265 umol/L, it is suggested that such patients can choose calcium channel blockers, which are often referred to as felodipine and amlodipine. For a hypertensive patient with sympathetic nerve excitation, blood pressure is only at the marginal value. It is suggested to take β-blockers, commonly known as metoprolol and bisoprolol, because these drugs can not only lower blood pressure, but also slow down heart rate, inhibit sympathetic excitability and prevent left ventricular remodeling.