Niergoline tablets (Fulutong) treatment: 1. Improve the low desire and emotional disorders (slow response, inattention, memory loss, lack of ideas, depression, anxiety, etc.) caused by cerebral arteriosclerosis and sequelae of stroke. 2, acute and chronic peripheral circulation disorders (limb vascular occlusive disease, Raynaud's syndrome, other peripheral circulation disorders. The following is the instruction manual of nicergoline tablets I have compiled. Welcome to read it. Product description of nicergoline tablets

Generic name: nicergoline tablets

Manufacturer: Hainan Zanbang Pharmaceutical Co., Ltd.

Approval number: National Medicine Zhunzi H19813

Drug specification: 1mg* 18 tablets

drug price: 26 yuan nicergoline tablets description

general name NicergolineTablets

product name nicergoline tablets (fulutong)

English name nicergoline tablets

pinyin full code nimaijiaolipin (fulutong)

the main component nicergoline, its chemical name is: 1? -methoxy -1,6- dimethyl ergoline -8? -Methyl alcohol -5- bromonicotinic acid vinegar.

chemical name: 1? -methoxy -1,6- dimethyl ergoline -8? -Methyl alcohol -5- bromonicotinic acid vinegar.

molecular formula: C24H26O3N3Br

molecular weight: 484.392

properties nicergoline tablets (fulutong) are sugar-coated tablets, which appear white or white-like after sugar coating is removed.

indications/functional indications: 1. Improve the low desire and emotional disorders (slow response, inattention, memory loss, lack of ideas, depression, anxiety, etc.) caused by cerebral arteriosclerosis and sequelae of cerebral apoplexy. 2, acute and chronic peripheral circulation disorders (limb vascular occlusive disease, Raynaud's syndrome, other peripheral circulation disorders < P > Specification model 1mg*18s

Usage and dosage: Take orally, do not chew. 2-6 mg (2-6 tablets) daily, taken in 2-3 times. The drug should be given continuously for enough time, at least six months, and it is up to the doctor to decide whether to continue the drug.

No serious adverse reactions have been reported. There may be hypotension, dizziness, stomachache, hot flashes, facial flushing, drowsiness and insomnia. In clinical trials, the concentration of uric acid in blood can be observed to increase, but this phenomenon has no correlation with the dosage and time of administration.

Niergoline tablets (Fulutong) are not suitable for the following situations: recent myocardial infarction, acute bleeding, severe bradycardia, orthostatic dysfunction, bleeding tendency and allergic to Niergoline.

note 1. it should be used under the guidance of a doctor. 2. Generally, nicergoline tablets (Fulutong) have no effect on blood pressure at the therapeutic dose, but may gradually lower blood pressure for sensitive patients. 3. Use with caution in patients with hyperuricemia or patients with gout history. 4. Renal insufficiency should be reduced. 5. Pregnant women are generally not suitable for use, and the pros and cons should be weighed when necessary. 6. It is forbidden to drink alcohol during taking medicine. Keep out of reach of children!

medication for children according to the current indications, this drug is not used for children.

Pharmacokinetics and tolerance tests of elderly patients showed that there was no difference in dosage and administration methods between adults and elderly patients.

The toxicity test of pregnant women and lactating women failed to show the teratogenic effect of nicergoline. The indications of this medicine show that this medicine is not used for pregnant women and lactating women.

drug interaction nicergoline tablets may enhance the effect of antihypertensive drugs. Because nicergoline is metabolized by CYTP452D6, interaction with drugs through the same metabolic pathway is not excluded.

overdose of nicergoline may cause a temporary decrease in blood pressure. Generally, you don't need treatment, just lie on your back for a few minutes. Rare cases have insufficient blood supply to the brain and heart, so it is suggested to give sympathomimetic drugs under continuous blood pressure monitoring.

Pharmacology and Toxicology Niergoline Tablets (Fulutong) are semi-synthetic ergotoxine derivatives. Have? -Receptor blocking and vasodilation. It can strengthen the energy metabolism of brain cells and increase the utilization of oxygen and glucose. Promote the conversion of neurotransmitter dopamine to increase nerve conduction, strengthen the synthesis of protein in the brain, and improve brain function. Nieergoline tablets (Fulutong) are semi-synthetic ergotoxine derivatives. Have? -Receptor blocking and vasodilation. It can strengthen the energy metabolism of brain cells and increase the utilization of oxygen and glucose. Promote the conversion of neurotransmitter dopamine to increase nerve conduction, strengthen the synthesis of protein in the brain, and improve brain function.

pharmacokinetics nicergoline is absorbed rapidly and almost completely after oral administration. The absolute bioavailability is less than 5%. The main metabolite of nicergoline is MMDL(1,6- dimethyl -8? -Hydroxymethyl -1? -methoxy-nicergoline) and MDL(6- dimethyl -8? -Hydroxymethyl -1? -methoxy-nicergoline). Most of nicergoline (> 9%) combined with plasma protein, to blood? The affinity of acid glycoprotein is higher than that of serum protein. In rats, [3H]-labeled nicergoline (5mg/kg) has a high radioactivity in the liver. Followed by kidney, lung, pancreas, saliva, lymph, spleen, adrenal gland and myocardium. The radioactivity in the brain is lower than that in the blood. After administration of [3H] and [14C] labeled nicergoline, renal excretion is the main attenuation route of radioactivity (about 8% of the total). The radioactivity in feces only accounts for 1~2% of the total. The pharmacokinetic parameters of nicergoline were compared among four groups of young volunteers (average 24~32 years old) and elderly volunteers (average 69~7 years old). The results showed that the pharmacokinetics of nicergoline was not affected by age. In patients with severe renal insufficiency, the excretion of MDL and MMDL in urine decreased significantly.

store away from light, and keep it sealed.

packaging 18 tablets/box.

expiry date: 36 months

Approval number: National Medicine Zhunzi H19813

Hainan Zanbang Pharmaceutical Co., Ltd.

Efficacy and role of nicergoline tablets (Fulutong) Treatment: 1. Improve the low desire and emotional disorder (slow response, inattention, memory decline) caused by cerebral arteriosclerosis and sequelae of stroke. 2. Acute and chronic peripheral circulation disorders (limb vascular occlusive disease, Raynaud's syndrome, other peripheral circulation disorders) Frequently asked questions about taking nicergoline tablets < P > Niergoline tablets belong to ergot alkaloids and have been put into clinical use for a long time. Nieergoline tablets not only have obvious therapeutic effect, but also have few side effects on human body, which has been well received by the majority of patients. So, can nicergoline tablets be taken for a long time?

nicergoline tablets can be taken for a long time, and the method of taking them is to take 1-2 tablets (5-1 mg) orally, three times a day, or as directed by the doctor. Niergoline tablets should be taken before meals to increase absorption or during meals to reduce irritation. During taking nicergoline tablets, it should be noted that patients should use nicergoline tablets according to the doctor's advice. Niergoline tablets can increase the effect of antihypertensive drugs, so it should be used with caution. Patients with poor renal function should be reduced. Generally speaking, nicergoline tablets should not be used in pregnant women, and the advantages and disadvantages should be weighed when necessary. It should be properly kept to prevent children from eating by mistake.

nicergoline tablets are clinically suitable for treating acute and chronic vascular or metabolic brain insufficiency (cerebral arteriosclerosis, cerebral thrombosis and embolism, transient ischemic attack). Nieergoline tablets are suitable for acute and chronic peripheral vascular dysfunction (Raynaud's syndrome, limb vascular occlusive diseases and other symptoms of peripheral circulation) and headache. Niergoline tablets can be used as adjuvant therapy for patients with arterial hypertension and hemiplegia after stroke. Niergoline tablets can improve the low desire and emotional disorders (insensitive, inattentive, memory decline, lack of ideas, depression, anxiety, etc.) caused by sequelae of cerebral infarction.

nicergoline tablets belong to ergot alkaloids, and its curative effect is rapid and definite, especially for tinnitus and vertigo, and its curative effect can be maintained for a long time. The mental state and the ability to respond to complexity of patients are obviously improved only 4 hours after taking the medicine, which is enough to prove that nicergoline tablets can effectively improve the brain activity function. Nieergoline tablets have high safety, little toxicity, little influence on blood pressure and heartbeat, and excellent tolerance after long-term use.