Clinically, it is often found that some patients have low prealbumin, so do you know? What is the reason for low albumin? In response to this question, the following are specific answers. ? Prealbumin (PALB) is a carrier protein, which is synthesized in the liver. The reference values of PALB for adults are 1 year 100mg/L, 1-3 years 168-28 1mg/ L and 280-360 mg/l. If it is lower than the above reference value, it means that albumin is low. If albumin is low, it can reflect the damage of liver cells, then what is it? There are mainly the following meanings. 1: acute inflammation, malignant tumor, liver cirrhosis or nephritis. Prealbumin is not only a sensitive nutritional protein index, but also the blood concentration of prealbumin often decreases in this case, resulting in low albumin. 2. liver disease. According to relevant data, 30% of patients with liver disease with normal albumin will have low albumin, and cirrhosis after necrosis can also have low albumin, even almost zero. Liver cirrhosis has mild necrosis of hepatocytes, little change of prealbumin and good prognosis. When the condition improves, prealbumin can also increase rapidly. 3. Subacute liver necrosis. In this case, albumin has been low, so prealbumin can be used as a prognostic indicator of liver disease. 4. Liver cancer and obstructive jaundice. All these patients can have low albumin, and the degree of reduction is closely related to the condition. Related reading: What should I pay attention to in liver function examination? What is the reason for the high AFP? Tips: What was the reason for the low albumin before? Low prealbumin is common in patients with advanced malignant tumor, chronic infection, liver cirrhosis, chronic active hepatitis and obstructive jaundice.