1) Liver-qi stagnation syndrome.
Main symptoms: right hypochondriac swelling and pain, chest tightness, aggravation after anger, decreased diet, hepatomegaly, thin and white tongue coating, and thready pulse.
Treatment: soothing the liver and relieving depression, regulating qi and relieving depression.
Prescription: Xiaoyao Powder (and Hejiju Formula). Bupleurum chinense 12g, Angelica sinensis 12g, Paeonia lactiflora 15g, Atractylodes macrocephala 10g, Poria cocos 10g, Radix Curcumae 10g, Rhizoma Cyperi 10g, Zagreb 30g and Zagreb 30g.
The pain in the liver area is very serious, such as Toosendan Fructus and Rhizoma Corydalis; Add Cortex Moutan and Fructus Gardeniae to soothe the liver and relieve depression and reduce fire.
Analysis: This prescription uses Bupleurum, Radix Curcumae, Rhizoma Cyperi and Pericarpium Citri Reticulatae Viride to soothe the liver, regulate qi, relieve depression and relieve pain; Angelica sinensis, Radix Paeoniae Alba and Semen Astragali Complanati soften liver and nourish blood; August Zha regulates qi and promotes blood circulation; Atractylodes macrocephala, Poria cocos and Glycyrrhiza uralensis Fisch are combined to soothe the liver, regulate qi and strengthen the spleen.
2) Qi stagnation and blood stasis syndrome.
Main symptoms: hypochondriac pain, backache, fixation, acute pain at night, anorexia, nausea, abdominal distension and tightness, fullness and hardness under hypochondriac, hiccups and belching, pale and dark tongue coating, particularly purple tongue edge, and unsmooth pulse.
Treatment: break blood stasis and disperse stagnation, promote qi and detoxify.
Prescription: Huayu decoction (Shaanxi traditional Chinese medicine 199 1, 1 1. 484)。 Radix Salviae Miltiorrhizae, Herba Hedyotidis Diffusae, Radix et Rhizoma Rhei and Carapax Trionycis preparata each 30g, Fructus Toosendan, Radix Angelicae Sinensis, Rhizoma Curcumae, Squama Manis and Fructus Gardeniae each15g, Radix Paeoniae Rubra and Rhizoma Cyperi preparata each 20g, five centipedes and Radix Curcumae10g.
Analysis: This prescription uses pangolin, zedoary and rhubarb to break blood stasis and disperse stagnation, Toosendan Fructus and vinegar Cyperus rotundus to regulate qi stagnation, Hedyotis diffusa and Gardenia to clear heat and detoxify, Salvia miltiorrhiza and Angelica sinensis to nourish blood, Carapax Trionycis to nourish yin and soften hardness, Turmeric to regulate qi and promote blood circulation, Scolopendra to soothe the liver and regulate qi, and the whole prescription mainly focuses on removing blood stasis, regulating qi and strengthening the body resistance.
3) Damp-heat syndrome of liver and gallbladder.
Main symptoms: pain in liver area, fever, jaundice, restlessness, insomnia, bitter taste, dry mouth, nausea and vomiting, loss of appetite, dry stool, short and red urine, depressed liver, hard quality with ascites, liver function damage, increased bile redness, red tongue or crimson, yellow and greasy fur, and thready pulse.
Treatment: Clearing away dampness and heat in liver and gallbladder.
Prescription: Longdan Xiegan Decoction (Hejiju Formula). 3g of gentian, 9g of scutellaria baicalensis, 0g of gardenia10g, 3g of akebiae, 9g of plantain, 9g of angelica, 9g of bupleurum, 9g of rehmannia glutinosa, 9g of Alisma orientalis and 3g of licorice.
Chest and abdominal pain, constipation, red and astringent urine, increased jaundice by 9g, and Trichosanthes kirilowii by 30g；; Artemisia scoparia 15g, Solanum lyratum Thunb. 24 and Curcuma aromatica12g; Added as jaundice; Adding Dendrobium 12g and Anemarrhena asphodeloides10g; Dry mouth; Ascites was added with 24g of raw Coicis Semen, 20g of Gynostemma pentaphyllum, and Polyporus umbellatus 15g.
Analysis: This prescription of Gentiana scabra clearing liver and purging fire, clearing damp-heat of lower jiao, clearing heat and purging fire of Scutellaria baicalensis Georgi and Gardenia, soothing liver of Bupleurum, activating blood of Angelica sinensis, and cooling blood and nourishing yin of raw land. There is tonic in diarrhea, nourishing in sparse, and purging fire does not hurt yin. Compatible with Akebia stem, Plantago asiatica and Alisma orientalis, it can expel damp heat from childhood, and use licorice to reconcile the medicines, purging fire and detoxifying. The whole prescription can not only purge excess fire in liver and gallbladder, but also clear damp-heat in lower energizer.
4) Spleen deficiency and dampness excess syndrome.
Main symptoms: bloating and sometimes diarrhea. Hepatomegaly, uneven hardness, slight damage to liver function, edema or ascites of lower limbs. The tongue is pale, the coating is thin and greasy, and the pulse is slippery or moist.
Treatment: Yiqi Jianpi Qushi.
Prescription: Sijunzi Decoction (Hejiju Formula). Codonopsis pilosula 15g, Atractylodes macrocephala 12g, Poria cocos 15g and Glycyrrhiza uralensis 4g.
Add Fructus Aurantii Immaturus and Cortex Magnolia Officinalis for abdominal distension, Massa Medicata Fermentata, Fructus Hordei Germinatus and charred Fructus Crataegi for diarrhea, Radix Linderae, Arecae Semen, Pericarpium Arecae, Lignum Dalbergiae Odoriferae and Lignum Aquilariae Resinatum for abdominal distension, and Semen Plantaginis, Polyporus, Rhizoma Atractylodis and Cortex Magnolia Officinalis for ascites.
Analysis: Codonopsis pilosula and Atractylodes macrocephala have the functions of invigorating spleen and benefiting qi. Poria cocos has light permeability, and it is combined with Atractylodes macrocephala to strengthen the spleen and promote diuresis. Glycyrrhiza uralensis Fisch is compatible with Codonopsis pilosula, which has the functions of benefiting qi and middle energizer. This recipe has the effects of invigorating spleen and qi, inducing diuresis and reducing swelling. It is suitable for the pathogenesis of liver cancer such as stagnation and ascites caused by spleen deficiency.
5) Yin deficiency of liver and kidney.
Main symptoms: hypochondriac pain, persistent pain, no appetite, low fever, night sweats, fever, dizziness, jaundice, red urine, or abdominal distension, blue veins exposed, vomiting blood, hematochezia, subcutaneous hemorrhage, red tongue with little coating, and thready pulse.
Treatment: nourishing blood and softening liver, nourishing yin and benefiting kidney.
Prescription: Yiguanjian (Liuzhou Medical Talk). Radix Glehniae 9g, Radix Ophiopogonis 9g, Radix Angelicae Sinensis 9g, Radix Rehmanniae 30g, Fructus Lycii 15g, and Rhizoma Chuanxiong 6g.
Heat vertigo, Ligustrum lucidum 15g, Eclipta prostrata 30g, raw tortoise plastron 20g, raw turtle shell 20g, Cornus officinalis 15g, low-grade night sweat 15g, Paeonia lactiflora 15g, Artemisia annua10g; Be added; 20 grams of Radix Astragali, 30 grams of Poria Skin and 30 grams of Lobelia Chinensis are added for fatigue and abdominal distension.
Analysis: Rehmannia glutinosa and Lycium barbarum are reused in this prescription to nourish yin and blood, so as to supplement the yin of liver and kidney; Adenophora adenophora, Ophiopogon japonicus and nourishing stomach and yin; Angelica sinensis nourishes liver and promotes blood circulation; Fructus Toosendan soothes the liver and relieves pain, but it is cold and not dry. The whole prescription nourishes liver and kidney, soothes liver and regulates qi.
(2) Single prescription
1) Angong Niuhuang Pills: Calculus Bovis, Radix Curcumae, Cinnabaris, Borneolum Syntheticum, Margarita, Gardenia, Realgar, Scutellariae Radix, Musk, etc. And making into pills.
Indications: resuscitation, spasmolysis, clearing away heat and toxic materials, and treating liver cancer.
Usage: Take one pill a day, swallow it or take it with warm water, and take 1 pill for 2 or 3 days after the effect is obvious.
2) Rectum purification solution for liver cancer: Astragalus membranaceus 30g, rhubarb 10g, salvia miltiorrhiza 15g, safflower 5g, seaweed 20g and dandelion 25g.
Indications: clearing away heat and toxic materials, invigorating qi and promoting blood circulation, and treating ascites and liver and kidney failure caused by advanced liver cancer.
Usage: decoct the medicine in water for 4 times, each time for 65438 0 hours, filter, combine filtrates, concentrate into thick paste, add 95% ethanol, and disinfect with ethanol. Enema with liquid medicine twice a day, 250ml each time, and try to keep it after enema. Five days is a course of treatment.
3) Cucurbitacin: Cucurbitacin is extracted from the pedicel of melon and made into tablets.
Indications: liver cancer.
Usage: Take orally, 0.3 m g at first, three times a day, and gradually increase to 0.5 ~ 0.6 mg 1.3 times a day. The safest and most effective oral dose for adults is 1.5 ~ 1.8 mg a day. A small number of patients have mild gastrointestinal reaction during medication, which can be easily relieved after symptomatic support treatment, and generally do not need to stop taking drugs.
4) Sophora japonica granules: Sophora japonica is processed into granules.
Indications: Primary liver cancer.
Usage: 1 time daily, 1 ~ 2 packs each time.
5) Spinning puffer fish skin: Spinning puffer fish skin into powder or encapsulating.
Indications: Primary liver cancer.
Usage: Take orally, 30 ~ 50g per day.
6) cinobufotalin: extracting and processing dried toad skin into injection.
Indications: clearing away heat and toxic materials, promoting diuresis and reducing swelling, and treating liver cancer.
Usage: intramuscular injection of 4ml each time, twice a day.
7) Maytenum injection: Maytenum is refined and processed into injection.
Indications: Primary liver cancer.
Usage: intramuscular injection 2 ~ 3 times a day, 2ml each time, 10 ~ 14 days as a course of treatment.
8) Lu Xian grass "B": Lu Xian grass is processed and refined to obtain an extract named Lu Xian grass "B".
Indications: clearing away heat and toxic materials, strengthening yang and tonifying kidney, stopping bleeding and promoting granulation. Treat liver cancer.
Usage: Take orally, 6g each time, 4 times a day.
9) Gelsemium: Gelsemium is used for grinding powder.
Indications: liver cancer.
Usage: Take 50mg orally, three times a day, and after three days, no response will increase to 100 ~ 150mg each time.
10) Rabdosia rubescens: Rabdosia rubescens is processed into syrup, tablet and injection.
Indications: liver cancer.
Usage: 30 ml three times a day. Take five tablets three times a day. Two dosage forms are used together, and 2-3 months is a course of treatment. Intravenous injection of 75 ~ 100 mg every other day 1 time.
(2) external therapy
1) Ruyi gold powder.
Main symptoms: pain of liver cancer.
Treatment: clearing away heat and toxic materials, reducing swelling and relieving pain.
Prescription: 50g of rhubarb, 0/00 g of trichosanthes root/kloc-,20g of borneol, 50g of cortex phellodendri, 20g of raw rhizoma arisaematis, 20g of frankincense, 20g of myrrh, 50g of turmeric, 50g of mirabilite, 50g of hibiscus leaves and 30g of realgar.
Grind the medicine * * into fine powder, mix it with maltose to make a thick paste, spread it on oily paper, with a thickness of about 3 ~ 5 mm and a circumference slightly larger than the lump, and apply it to the lump or pain in the liver area. Change medicine every other day 1 time, twice for 1 course of treatment, and stop using all analgesic drugs during the application period. If papules or herpes appear on the local skin after application, stop using until the local skin returns to normal.
Analysis: this prescription uses rhubarb, phellodendron bark, hibiscus leaves and trichosanthes root to clear away heat and purge fire, detoxify and reduce swelling; Olibanum, Myrrha, Curcuma longa promote blood circulation, regulate qi, relieve swelling and pain, Rhizoma Arisaematis, Natrii Sulfas, Borneolum Syntheticum and Realgar resolve phlegm and soften hardness, and relieve swelling and pain. This prescription has certain detumescence and analgesic effects, and can treat the pain of liver cancer.
2) Ai Tong powder.
Main symptoms: pain of liver cancer.
Treatment: clearing away heat and toxic materials, reducing swelling and relieving pain.
Prescription: Rhizoma Kaempferiae, Olibanum, Myrrha, Radix et Rhizoma Rhei, Curcuma Rhizome, Fructus Gardeniae, Radix Angelicae Dahuricae and Scutellariae Radix each 20g, Fructus Foeniculi, Flos Caryophylli, Radix Paeoniae Rubra, Radix Aucklandiae, Cortex Phellodendri each/kloc-0.5g, and Semen Ricini 20 tablets.
Grind the medicine into powder, take proper amount of egg white, mix, stir evenly into paste, apply it to Qimen point, then cover it with gauze or wax paper and fix it with adhesive tape. If the pain is severe, change the dressing 1 time within 6 hours; if the pain is mild, change the dressing 1 time within1time within 2 hours, which can be used continuously until the pain is relieved or disappeared.
Analysis: this prescription uses rhubarb, gardenia, scutellaria baicalensis and phellodendron amurense to clear away heat, diminish inflammation and relieve pain; Rhizoma Kaempferiae, Radix Angelicae Dahuricae, Fructus Foeniculi, Flos Caryophylli, and Radix Aucklandiae have fragrant smells, and can regulate qi, dissipate stagnation, and relieve pain. Olibanum, Myrrha, Curcuma Rhizome and Radix Paeoniae Rubra are used for promoting blood circulation, removing blood stasis, relieving swelling and pain; Castor seed not only has the functions of detoxification, detumescence and pain relief, but also contains a lot of fatty acids, so it is an excipient. Qimen point is the receiving point of the liver meridian, which is applied to the point by gathering the qi of the meridian. Compared with simple pain points, it can better exert its efficacy.
(3) Acupuncture treatment
1) needle square 1.
Key points: Hepatitis point (straight down the right clavicle midline, 2 inches below the costal arch), Zusanli ST36.
Matching points: Yanglingquan GB34, Qimen LR 14, Zhangmen LR 13, Sanyinjiao SP6.
2) Needle square 2.
Main acupoints: Baihui point, bilateral epigastric area (scalp acupuncture), Neiguan PC6 and Sanyinjiao point.
Matching points: Ganshu BL 18, Shenshu BL23, Mingmen DU4, Oichi.
(4) Qigong therapy
While preparing for the treatment of traditional Chinese and western medicine, patients should insist on practicing Qigong, which can improve symptoms, improve quality of life and prolong life.
1) Practice essentials.
① Continue the original radiotherapy and chemotherapy scheme.
② It is suitable for patients with liver cancer in the middle and early stage, and has certain physical strength and can complete acrobatic activities.
(3) Pay attention to what you can, step by step.
2) Common methods of achievement.
① Double major (omitted here).
② Soothing the liver and regulating qi (omitted here).
③ Cutting (omitted here).
(5) medicated diet therapy
1) Braised eggs of Mylabris: 2 Mylabris, eggs 1 egg. Function: breaking blood, dispersing stagnation, attacking poison and resisting cancer. Make a small hole in the egg shell, put in Mylabris (head and feet removed), seal it with cotton paper, simmer, remove Mylabris and eat the eggs.
2) Stewed pork with peach root: fresh peach root100g, lean pork 200g. Function: clearing away heat and toxic materials, promoting diuresis and promoting blood circulation. Add water to the pot, simmer until the meat is cooked, eat meat and drink soup.
3) Gecko wine: live Gecko 5 ~ 10 tablets, white wine 500g(60 degrees). Has the functions of resolving hard mass and relieving pain. Put the live gecko in a tin can or brown bottle filled with wine and put it in the dark, usually for 7 days. Drink 10ml 2 ~ 3 times a day.
4) toad powder: 1 ~ 2 toad, which has the functions of detoxification, detumescence and pain relief. The skins, hearts, livers and eyes of two toads were baked on tiles, ground into fine powder and divided into 5 packages. Take a toad, remove the five internal organs, add water to simmer, and let it cool into peptone. Take 1 powder every time, twice a day, with yellow wine delivered. Take 1 dose of medicinal peptone every time, and take 1 time every other day.
5) Indocalamus porridge: Indocalamus leaves 60g, and appropriate amount of japonica rice, which has the functions of detoxification, detumescence, hemostasis and pain relief. First, add water to the Indocalamus leaves to get juice, and then add stem rice to cook porridge. Take porridge twice in the morning and evening.
6) Red fish meal: 65438+ red fish tail 0 big thorn (2 small thorns). Roast the fishbone and grind it. Has the functions of clearing away heat, diminishing inflammation, resolving hard mass and eliminating diseases. Daily 1 time, with warm boiled water.
7) stewed eggs with lotus root juice at the end of Tianqi: Tianqi 2 ~ 3g, lotus root juice 30ml, fresh eggs 1 egg. Function of removing blood stasis, relieving pain and stopping bleeding. Shell the eggs, put them in a bowl and stir, add lotus root juice (fresh lotus root is washed, peeled and squeezed) and Tianqi powder, mix well and add a little rock sugar. Patients with liver cancer should eat properly when vomiting blood or bloody stool.
8) Chicken bone grass and candied dates lean broth: 7-8 pieces of chicken bone grass with 30g of candied dates and lean pork 100g. Function of clearing heat, promoting diuresis and eliminating jaundice. Boil the last three samples with water, add a little salt to taste, remove the residue and eat soup and meat.
2. China-DPRK medical care
Early patients with liver cancer can choose sweating soup, Jiedu soup and Manyongguan according to their condition.
Sweating soup: ephedra 16g, cinnamon 12g, gypsum 16g, almond 6g, licorice 4g, 5 slices of ginger and onion 1. In addition, external application of pork can treat external cancer.
Jiedu Decoction: Coptidis Rhizoma, Trichosanthis Radix, Radix Puerariae and Radix Rehmanniae each 8g, Ginseng Radix, Fructus Schisandrae, Radix Platycodi, Fructus Aurantii, Rhizoma Chuanxiong, Atractylodis Rhizoma, Radix Paeoniae Alba, Gypsum Fibrosum, Radix Glycyrrhizae and Alismatis Rhizoma each 4g, and 3 slices of ginger.
Slow-swimming ointment: 65438 00 kg of Rehmannia juice, 2 kg of ginseng powder 1 kg, 2 kg of Poria powder, 6 kg of honey, 65438 00 kg of Radix Asparagi and Lycii powder, 300 g of Radix Ophiopogonis and Cortex Lycii powder, and 600 g of Radix Codonopsis powder ... Mix the medicines evenly, put them in a porcelain jar, seal them with oil paper, and fry them in a copper pot with slow fire.
3. Mongolian medicine is in China
Main symptoms: poor appetite at first, fullness in the upper abdomen, weakness and burning pain in the right upper abdomen. When the disease worsens, the pain is severe and unbearable, which leads to rapid weight loss, fever, fatigue, sometimes nausea and loss of appetite. The tumor in the liver is getting bigger and bigger, and the pain is getting worse. Tumors can be felt in the liver area, sometimes swelling, Huang Chi loose stool, difficulty in defecation, red tongue with yellow greasy coating, and rapid pulse.
Treatment: clear away Sheila and blood heat, relieve heat toxin in liver, break liver hematoma, and take laxatives to eliminate diseases and pathogens.
Prescription: Chagan Bangga Qingxue Shiwei Powder: Chagan Bangga 30g, Momordica cochinchinensis and Shell Tooth Ash 65438 08g, Baishaga, Calculus Bovis, Cortex Phellodendri, Herba Violae, Oletum Trogopterori, Eupatorium, Black Ice Tablet and Nutmeg 65438 05g, Flos Caryophylli, Folium Forsythiae 9g, Fructus Forsythiae 8g, and bear gall/nutmeg 9g.
Eight kinds of turquoise powder: turquoise 15g, plum blossom slice 6g, Dalbergia odorifera 12g, clove 12g, safflower 12g, bear gall 3g, inch incense 0.5g, and ground into powder.
The upper two sides are taken alternately with boiling water.
Thirteen powders of safflower can also be used: saffron 10g, clove 5g, bezoar 5g, musk deer 5g, rhinoceros horn 5g, Yinzhu 5g, Dalbergia odorifera 5g, Datuo marble 5g, Chaganbangjia 5g, terminalia chebula 5g, Toosendan 5g, Gardenia 5g and Radix Aucklandiae 5g.
Take 30 grams of thorn fruit and 30 grams of trogopterori, and dry the liver blood; White sandalwood and safflower 3g each; * * * Grind into fine powder, soak in 120g Chinese liquor, ferment for 3-7 days, then add 60g rock sugar and stir to paste, twice a day, and take 1 spoon each time.
After taking eight antidiarrheal agents (the prescription content is not listed in the data).
Acupuncture can be applied to the internal and external veins of elbow when taking medicine.
4. China went back to the doctor for treatment.
Prescription: 20g of cowpea, 20g of hydrangea macrophylla, 30g of Herba Artemisiae Scopariae, 20g of Alisma orientalis, 0/5g of Rhizoma Sparganii and 0/5g of Rhizoma Curcumae.
Usage: decoct in water for 4 times, each time 15 minutes, mix the liquid medicines, and take it four times, each time 1 cup, daily 1 dose.
Indications: This recipe has the effects of clearing away heat and toxic materials, promoting diuresis, promoting blood circulation to remove blood stasis, promoting qi circulation and relieving pain. It is suitable for patients with liver cancer in the early and middle stages, heat toxicity, damp-heat stasis, qi stagnation and blood stasis, scleral jaundice, liver fullness and pain, vexation and retching, bitter mouth and dry throat.
Prescription: serpentine (Selaginella northeast) 20g, hydrangea 30g, rabdosia japonica 20g, areca catechu 20g, dragon's blood 15g.
Usage: decoct in water for 4 times, 20 minutes each time, and combine the liquid medicines. People should take 1 teacup four times, 1 dose every day, and add a little urine (20ml) as a guide.
Main symptoms: This recipe has the functions of dredging meridians, removing blood stasis and relieving abdominal pain. It is suitable for patients with liver cancer such as large and hard liver, abdominal distension, sudden blue veins, hypochondriac pain and constipation. Do not eat spicy, fragrant and dry food during taking medicine.
5. Easy medical care
Prescription: 30g of Solanum lyratum Thunb. ), Aralia elata 30g, Agrimonia pilosa 30g, Aralia elata 15g, Astragalus membranaceus 30g, Panax notoginseng 3g and Lycium barbarum 30g.
Indications: This prescription is effective in the treatment of liver cancer, with good curative effect on middle and early stage patients and poor curative effect on late stage patients.
Usage: Except for Notoginseng Radix, take Notoginseng Radix three times after decoction. Daily 1 dose, morning, noon and evening 1 time.
Second, Japan's research on traditional Chinese medicine prescriptions for the treatment of liver cancer
(1) Buzhong Yiqi Decoction combined with Guizhi Fuling Pill: Buzhong Yiqi Decoction combined with Guizhi Fuling Pill was used for cases of liver cirrhosis complicated with liver cancer and multiple lung metastases after hepatic artery embolization. On the 45th and 90th day after taking the medicine, the original shadow disappeared on the second chest radiograph, and only the shadow of the right lower lobe 1 nodule was displayed on the chest CT. Chinese medicine is the main treatment here, and all anticancer drugs are stopped. After another two months, AFP turned normal (19ug/ml), cirrhosis and liver abscess remained unchanged, and the patient was in good spirits, with no special complaint and normal life. [Ri Hoshino, Japanese Oriental Medical Journal,1992; 42(4):409〕。
(2) Xiaochaihu Decoction: Patients with liver cirrhosis with AFP below 200 ug/L were randomly divided into two groups, each group 130 cases. Generally speaking, the two groups used the same drug. The drug group was given Xiaochaihu decoction 7.5g/d. All patients were examined for alpha-fetoprotein every two months and ultrasound every three months. 84 cases in the treatment group and 8 cases in the control group were observed for 57 months. There were 26 cases of liver cancer in the medication group and 35 cases in the control group. Except for those who found liver cancer within 6 months after the start of the study, there were 23 cases in the treatment group and 365,438+0 cases in the control group. At the 57th month, the cumulative incidence was significantly different (P = 0.039). The AFP value in the medication group was lower, which was significantly different from that in the control group. [Yoo Yamamoto, Internal Medicine,1991; 67(4):65 1〕。