The liver of puffer fish is highly toxic, and people are not allowed. Because the puffer fish is the most toxic place is ovaries and liver, followed by kidneys, blood, eyes, gills and skin. The size of the toxicity of the puffer fish is also related to its reproductive cycle, the puffer fish with eggs in late spring and early Xia is the largest. The toxin of puffer fish can make people nerve paralyzed, vomiting, four branches of the cold, and then heartbeat and respiratory arrest.