Gypsum is a commonly used tofu coagulant, which is a natural mineral that is non-toxic, odorless, and has no side effects. Lactone is a new type of coagulant, which is composed of substances such as gluconolactone and calcium chloride, and is also a non-toxic, odorless, and side-effect-free coagulant. Salt brine is a traditional coagulant for tofu, which is made from seawater or salt lake water, and contains high levels of sodium chloride and other minerals that may have some impact on human health.