Dose-related nausea, vomiting, facial flushing and dizziness may occur with non-intestinal use. Therefore, these reactions may also occur when this product is applied in overdose. However, Salmon Calcitonin Nasal Spray has been used at a single dose of 1600 IU and 800 IU daily for 3 days without causing any serious adverse reactions. Individual cases of overdose have been reported. Symptomatic management is required.