Fritillaria cirrhosa is not suitable for people. Bulbus Fritillariae Cirrhosae is a kind of Chinese herbal medicine, which can play a health care role in human body if eaten reasonably. But Fritillaria cirrhosa is not suitable for everyone. Only by knowing your own physique can you keep healthy. Share that Fritillaria cirrhosa is not suitable for people to eat.
Fritillaria cirrhosa is not suitable for 1 infant.
The various systems of infants are still in the stage of growth and development. If you have a cough, giving your baby drugs like Fritillaria cirrhosa will do great harm to your baby and affect your growth and development. The baby should be breast-fed at this time. Breast milk contains a lot of antibodies to help them resist the entry of foreign bacteria. Therefore, the baby must not eat Fritillaria cirrhosa when coughing, and the consequences are very serious. The best way is to help dad improve his physical fitness through breastfeeding.
pregnant woman
Pregnant women accidentally caught a cold, and it is not good to eat Fritillaria cirrhosa blindly when coughing. Although, after taking it for a long time, the cough symptoms will be relieved, but it has a great influence on the baby in the belly. Fritillaria cirrhosa is very irritating and will stimulate the growth of the baby in the body. In addition, the pungent smell of Fritillaria cirrhosa will also aggravate the morning sickness of pregnant women.
diabetic
Once Fritillaria cirrhosa is used as medicine to treat cough, there will be a lot of sugar to cooperate. Because it can only be preserved with sugar, and the cough relieving effect is better. Then, this is not suitable for diabetic patients, and it will increase the sugar powder content of diabetic patients. We all know that the most troublesome situation of diabetes is the high sugar content in the body, which is very unfavorable to our health. Therefore, if you want to be healthy, you must learn to avoid this situation, otherwise it will deepen the development of the disease. So it is not suitable for diabetics.
deficient cold of spleen and stomach
Although Fritillaria cirrhosa has a good effect of relieving cough and resolving phlegm, it is a cold food. For those patients who are weak and cold, if they take Fritillaria cirrhosa again, it is likely to make matters worse and their bodies will be hit hard. At that time, coughing was not limited, but also aggravated spleen and stomach deficiency and cold. Although we all know that Bulbus Fritillariae Cirrhosae is a very good food, taking Bulbus Fritillariae Cirrhosae regularly in our life is good for our health, but Bulbus Fritillariae Cirrhosae is a cold food after all, and people with deficiency of spleen and stomach should not take Bulbus Fritillariae Cirrhosae.
Fritillaria cirrhosa is not suitable for crowd 2. Function and efficacy of Fritillaria cirrhosa
Bulbus Fritillariae Cirrhosae has the effects of moistening lung, relieving cough, resolving phlegm, relieving asthma, clearing away heat and resolving phlegm, and can be used for treating heat-induced cough, such as wind-heat cough, dry-heat cough and lung-fire cough. Fritillaria cirrhosa has antitussive, expectorant, antihypertensive and antibacterial effects.
Indications: chronic cough due to lung deficiency, fatigue cough, dry cough, scanty phlegm, expectoration with blood, lung abscess, carbuncle and breast carbuncle.
Effects on respiratory system
Antitussive effect
Fritillaria cirrhosa has antitussive effect. The experiment of inducing cough with ammonia in mice was carried out. Tissue culture of Fritillaria cirrhosa and wild Fritillaria cirrhosa has the strongest antitussive effect at 30 minutes, and the antitussive rate is over 50%. After 1 hour, the effect began to decline, and it still had significant effect until 2 hours. At the dosage of 1.5g/kg and 3.0g/kg, the antitussive effect increased with the increase of dosage. Tissue cultured Fritillaria cirrhosa and commercial Fritillaria cirrhosa have similar antitussive and expectorant effects.
The total alkaloids and non-alkaloids of Fritillaria cirrhosa were taken orally at 0.25 ~ 0.5mg/ mouse, which had obvious antitussive effect. The total alkaloids and Fritillaria saponin ⅰ, ⅱ and ⅲ extracted from wild and cultivated Fritillaria thunbergii in northwest Sichuan were detected by mouse sulfur dioxide induced cough method. The alkaloids had no antitussive effect. 0.2g/kg Fritillaria saponin Ⅱ can obviously prolong the cough latency in mice, showing antitussive effect.
Another scholar used * sodium 15mg/kg and * sodium 75mg/kg to give cats mixed abdominal anesthesia, and electrically stimulated the superior laryngeal nerve to induce a typical and stable cough response. After intraperitoneal injection of 4g/kg ethanol extract from northern Anhui (crude drug), it was stimulated every 20 minutes according to the original conditions. The results showed that the cough intensity and cough times of cats were inhibited to varying degrees after taking the medicine, and the cough relieving effect was remarkable for 60 minutes, lasting for 2 ~ 3 hours. Compared with Bulbus Fritillariae Cirrhosae, there is no significant difference in antitussive effect between them. Compared with Zhejiang shellfish, Anhui shellfish has a better antitussive effect. Therefore, Fritillaria Anhui can be used as a substitute for Fritillaria cirrhosa.
Expectorant action
The experimental study shows that Fritillaria cirrhosa cultivated artificially, wild and tissue cultured has obvious expectorant effect. Phenol red excretion experiment in mice showed that Fritillaria cirrhosa 200% fluid extract, Fritillaria cirrhosa alkaloids 1 1.3mg/kg and Fritillaria saponin ⅰ ~ ⅲ all had obvious expectorant effects, among which alkaloids and saponin ⅲ had stronger effects. Intraperitoneal injection of 3.9g/kg tissue-cultured Fritillaria cirrhosa and wild Fritillaria cirrhosa in mice also had expectorant effect, and the effect of 1 hour reached its peak after administration, and weakened after 2 hours. The expectorant effect is enhanced with the increase of dosage.
Rats were given 15g/kg (crude drug) by gavage or 26mg/kg total glycosides by oral administration. The results showed that the respiratory secretion increased obviously after administration, and the minimum effective amount of total glycosides was 12mg/kg, and the maximum effective amount was 59mg/kg. In this range, the expectorant effect is enhanced with the increase of dose.
Influence on circulatory system
Fritillaria cirrhosa has antihypertensive effect. Intravenous injection of Bulbus Fritillariae Cirrhosae 4.2mg/kg in cats can cause continuous blood pressure drop, accompanied by short-term respiratory depression. Sibelium also has antihypertensive effect on anesthetized dogs; A very small amount of peimine A and peimine B can raise blood pressure. A large number of alkaloids can lower blood pressure.
Antibiotic action
Fritillaria cirrhosa has certain antibacterial effect. 2mg/l can inhibit the growth and reproduction of Escherichia coli and Staphylococcus aureus. The alkaline water extract of Fritillaria cirrhosa (1∶25) has inhibitory effect on Nocardia stellata in vitro.
side effect
0. 1.2 mg/kg ethanol extract of Fritillaria. There were no abnormal changes in respiration, blood pressure and electrocardiogram after intraperitoneal injection in cats. Rats and mice were given 12g/kg ethanol extract (or Wanbei powder suspension, equivalent to the clinical dosage of 120 times) by gavage and observed for 7 days. The results showed that rats and mice were as active as usual, and their coat color and food intake were within the normal range. The minimum lethal dose of ethanol extract to mice is 40g/kg, which is more than 300 times of the clinical dosage.
Long-term toxicity test: 9 guinea pigs and 4 rabbits were given 6g/kg ethanol extract from northern Anhui for 20 days. Routine pathological sections of trachea, heart, liver, lung, kidney, brain, esophagus, gastrointestinal tract, pancreas and adrenal gland were examined. It was found that goblet cells in trachea and bronchial mucosa proliferated and hypertrophy, and the secretion in lumen was obviously thin, and no abnormal changes were found in other organs.
Second, who is not suitable for eating Fritillaria cirrhosa?
Fritillaria cirrhosa generally has no side effects, but it needs to be eaten in moderation, and some special people should not blindly use Fritillaria cirrhosa. For example, pregnant women, children and the elderly should be under the guidance of doctors. For children and the elderly, we should also treat them differently, and don't buy medicine for ourselves, because the whole body function of the elderly is in a low state, and any medicine may have adverse reactions. So take it according to the doctor's advice. It should be noted that Bulbus Fritillariae Cirrhosae is mainly suitable for dry and hot cough, characterized by dry mouth, less thick phlegm, yellow color, sore throat, or accompanied by fever, headache and other symptoms. However, if you have a cold and cough, taking Fritillaria Fritillaria powder is like "adding insult to injury", which is very inappropriate and must be cautious. If the mouth is pale and thirsty, the throat is itchy, mainly coughing at night, and the sputum is thin and white, it is not suitable for use.
In addition, Fritillaria cirrhosa tastes bitter, sweet and slightly cold; Return to lung meridian and heart meridian; The quality is moist and scattered, and it drops slightly; Has the effects of clearing away heat, resolving phlegm, moistening lung, relieving cough, resolving hard mass and reducing swelling; Treat chronic cough, lung fever, dry cough, lung abscess, pus, tuberculosis, breast abscess and sores caused by fatigue. Therefore, people with weak spleen and stomach, cold phlegm and wet phlegm should not use it with caution.