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What tests can be used to diagnose pancreatitis?

1 Trypsin assay

Serum amylase assay is the most widely used diagnostic method. The increase in serum amylase can be measured within 24 hours after the onset of disease, and the serum amylase value increases significantly >500 U/dl (normal value 40-180 U/dl), and gradually drops to normal within the next 7 days.

A significant increase in serum lipase (normal value 23-300U/L) is a more objective indicator for the diagnosis of acute pancreatitis. The consistency of serum amylase isoenzymes improves the accuracy of the diagnosis of this disease. The diagnosis of acute pancreatitis can be ruled out when serum amylase is elevated but P-isoenzyme is not elevated.

2 Urine amylase measurement

Urine amylase measurement is also a sensitive indicator for diagnosing this disease. Urinary amylase rises slightly later but lasts longer than serum amylase. A significant increase in urinary amylase (normal value 80-300U/dl) has diagnostic significance. The higher the amylase measurement value, the higher the accuracy of diagnosis. However, the amylase value is not necessarily directly proportional to the severity of the disease.

3. White blood cell count examination

In mild pancreatitis, the white blood cell count may not increase or may increase slightly. However, in severe cases and accompanied by infection, the white blood cell count often increases significantly, and neutrophils also increase.

4 Chest X-rays

Left lower lobe atelectasis, left hemidiaphragm elevation, left pleural effusion, etc. reflect inflammation around the diaphragm and retroperitoneum. It supports the diagnosis of acute pancreatitis but lacks specificity and is an auxiliary diagnostic indicator.