The plasma concentration reached its peak 3 hours after oral administration, and its absorption was dose-dependent. The product was detected in blood, kidney, adrenal gland, pancreas, liver and stomach in turn, with high concentration, but low concentration in muscle, testis and brain nerve. Eight hours after administration, the total excretion of B 12 in urine is 40% to 80% of that in 24 hours after administration.
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Mecobalamin can not only repair nerves, but also be used for these five common diseases. Learn more information in case you need it.
1, neurodermatitis
Neurodermatitis is a chronic inflammatory skin disease with unknown etiology. After the onset of severe pain, mostly in the neck, arms, elbows, wrists, calves, coccyx, anus and other parts. After the onset of neurodermatitis, it seriously affects people's normal life and reduces their quality of life.
Because of itchy skin, patients can't help scratching hard, which leads to the deterioration of local skin condition and neurodermatitis. The age is about 30~50 years old. Sticking to oral mecobalamin can relieve the symptoms of nerve itching and treat neurodermatitis.
2. Ophthalmic diseases
Studies have shown that the use of mecobalamin in the treatment of glaucoma can alleviate the damaged eye health and promote the recovery of visual function. It is also found that mecobalamin can effectively protect the human central nervous system from various factors.
When it comes to glaucoma, everyone should be familiar with it. This kind of problem bothers many people. In severe cases, it will cause blindness, and the incidence rate is about 10%. This is an optic nerve disease, which will damage people's normal visual function.
Mecobalamin can play a certain affinity with local nerves after ingestion. Among all kinds of drugs to improve nerve regeneration function, various studies show that in the treatment of visual impairment caused by glaucoma, patients can control intraocular pressure more effectively. The treatment of intramuscular injection in the first three weeks, followed by oral medication, can effectively inhibit the deterioration problem for about 100 days.
3, bone and joint pain
If you don't pay attention to bone maintenance in your daily life, you are prone to lumbar diseases, such as pain caused by oppression, or prominent problems. After mecobalamin treatment, it can effectively restore local nerve injury and improve neuralgia caused by bone injury.
However, for bone diseases, mecobalamin can only play a certain role in relieving the disease, and it cannot be fundamentally treated. In order to make the disease fully recover, we should start with the root causes and formulate various treatment plans in a targeted manner to accelerate the good repair of bones.
4. Treat facial muscle atrophy
Facial paralysis is a very common disease, mainly caused by acute facial edema. In the acute stage of the disease, glucocorticoids can also be used for treatment to reduce nerve edema, shorten the course of disease and improve the prognosis.
At the same time, combined with the treatment of mecobalamin, this drug can also play a role in nourishing nerves, which can reduce the edema of facial nerve and thus improve local muscle paralysis.
5, megaloblastic anemia
The main causes of megaloblastic anemia are the lack of vitamin B 12 and folic acid, which leads to the lack of coenzyme, the obstruction of DNA synthesis, the prolonged mitosis and the increase of RNA synthesis, which leads to the unbalanced development of nucleus and cytoplasm, making the nucleus reticular and unable to retract and fix, resulting in huge cells, but the nucleus is still immature.
Oral mecobalamin can effectively promote the repair and regeneration of blood cells and prevent megaloblastic anemia.
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What should I pay attention to when taking mecobalamin?
1. People who work with mercury and its compounds should not take this preparation in large quantities for a long time.
2. After taking the medicine, be sure to tighten the bottle cap in time and store it in a cool and dark environment where children can't reach it to prevent children from eating by mistake.
3. Avoid repeated injections at the same site. Newborns, premature babies and infants should pay special attention. Pay attention to avoid areas with dense nerve distribution. Attention: If there is severe pain or blood reflux during needle insertion, you should immediately pull out the needle and inject it in another place.
4, continuous medication for more than a month without obvious relief, need to see a doctor in time to find out the reason, so as not to delay the best treatment time of the disease.
5, pregnant women or pregnant women, in the process of medication, must be taken in strict accordance with the doctor's guidance and advice, so as not to have a greater impact on the fetus in the abdomen.
6, the elderly or people with weak constitution, mainly according to personal circumstances gradually reduce the dose.
7. Before taking the medicine, observe the characteristics and color of the medicine clearly. Please stop taking the medicine as soon as you find it expired or volatilized.
8. In case of dizziness, headache, general fever, rash, local lump, blood pressure drop, dyspnea and other abnormal manifestations, and there are side effects and allergic reactions to drugs, you should stop taking drugs immediately and seek medical advice in time.
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Extension-What is the difference between mecobalamin and vitamin B 12?
Vitamin B 12 is one of the B vitamins, also known as cobalamin. It is a newly discovered vitamin and the only vitamin containing cobalt.
Vitamin B 12 plays an important role in promoting the development of red blood cells, maintaining the health of nervous system and synthesizing protein. Vitamin B 12 is a macromolecular structure and cannot be directly absorbed by human body. After entering the human body, it will be released in the form of hydroxyl tube, and then converted into mecobalamin to play a role.
Mecobalamin is a decomposed vitamin B 12, which can function without biotransformation after entering the human body, and is more easily absorbed by the human body than vitamin 12.
Although the structure of mecobalamin is similar to that of vitamin B 12, the two drugs cannot be taken as the same drug. People who take vitamin B 12 should not use mecobalamin instead, and people who take mecobalamin should not use it. Vitamin B 12 should be used instead to avoid drug allergic reaction.