(Classic)

Different names continue to poison (Ben Jing), Sichuan stellera venom (Ji Xiao Fang).

The source is Stellera chamaejasme of Daphne family or the root of Euphorbia fischeriana and Euphorbia lunata of Euphorbiaceae family.

Plant morphology ① Stellera chamaejasme, also known as: Herba Lysimachiae, Bowl Flower, Shandan Flower, Stuffy Flower and a handful of incense.

Perennial herb, 20 ~ 40 cm tall. The root is cylindrical. The stems are tufted, smooth and hairless, and the lower part is woody, brownish or reddish. Simple leaves alternate and dense; Narrow ovate to linear, long1~ 3 cm, wide 2 ~10 mm, entire, glabrous on both sides; Slightly leathery when old; Petiole is extremely short. The head is terminal, about 2.5 cm in diameter, with many flowers; The calyx is often flower-crowned, white or yellow, with purplish red, the calyx tube is thin and tubular, the apex is 5-lobed, and the lobes are flat, oblong to obovate; Stamens 10, born in 2 rows in throat; The ovary is superior, the upper part is densely hairy, the style is short, and the stigma is head-shaped. Fruit ovoid, enclosed by perianth tube base. Seeds 1 piece. The flowering period is from May to June.

Born in mountains and grasslands. Distributed in Northeast China, North China, Northwest China and Southwest China.

② Euphorbia fischeriana

Perennial herbs, height15 ~ 40 cm, all containing white milk. The roots are fleshy. The lower leaves of the stem are scaly, membranous and light brown; 3 ~ 5 middle and upper leaves are whorled and sessile; Leaf blade oblong or oblong-ovate, 4 ~ 6.5 cm long and1~ 3 cm wide. The apex is obtuse or acute, and the base is round. Cup-shaped cymes are terminal and arranged in a compound umbrella shape; Pedicel 5 branches, basal whorled leaflike bracts 5; Each branch is further divided into three branches, with three triangular ovate bracts at the branches, two smaller bracts and1~ 3 cup-shaped cymes at the tip of the branch; Most male flowers and female flowers 1 piece are born in the cup-shaped involucre, the apex of involucre is 5-lobed, and 5 glands alternate with lobes; Male flowers only have stamens1; The female flower has only pistil 1, the ovary is oblate, the style is 3, and the apex is shallowly divided into 2 forked stigmas. Capsule oblate, with 3 longitudinal grooves, brown. The flowering period is from May to June. The fruiting period is from June to July.

Born on hillsides and sunny places in Shan Ye. Distributed in Northeast China and Hebei, Inner Mongolia, Shanxi and other places.

③ Euphorbia lunata

Perennial herb, 30 ~ 50 cm tall. Leaves alternate; Leaf blade narrowly elliptic or elliptic-lanceolate, 4-8 cm long and1.5-2 cm wide, with rounded apex and wedge-shaped base. Cup-shaped cymes arranged in a compound umbrella shape; There are 5 pedicels, and 4 ~ 5 leaflike bracts are ovate-lanceolate or triangular-oblong at the base. Each branch is divided into 2 branches, with 2 triangular or broadly ovate bracts at the branch, and 2 smaller bracts and 1 cup cyme at the tip of the twig; Male and female flowers are born in the calyx-cup-shaped involucre, with 4 lobed tips and 4 glands. Capsule smooth and hairless. The flowering period is from May to June.

Born on a hillside or in the grass under a forest. Distributed several times throughout the country.

Collecting and digging in spring and autumn, removing stems, leaves and silt, and drying in the sun.

Medicinal material ① Stellera chamaejasme

Also known as: Euphorbia, Radix Raphani (Herbal Medicine in Southern Yunnan), General, Stellera chamaejasme, and Stellera chamaejasme in Northwest China. It is the dry root of Stellera chamaejasme, which is conical to long cylindrical, slightly twisted, 7 ~ 30 cm long and 2 ~ 7 cm in diameter; Above-ground stem residues are left at the root head; The appearance is brown to brown, with longitudinal wrinkles and transverse slender lenticels, and sometimes fine roots remain. After the cork peels off, soft fibers are exposed. It is light, tough and not easy to break. The xylem in the center of the section is yellow and white, and the phloem in the outer ring is white and fibrous. Slight gas, slightly sweet, slightly bitter and spicy.

Inner Mongolia, Shanxi, Henan, Qinghai, Gansu, Shaanxi, Sichuan and other places.

② White Wolf Poison

It is the dried root of Euphorbia fischeriana and Euphorbia lunata, all of which are cut into round pieces.

Euphorbia fischeriana

Also known as: cat's eye flower root, northeast wolfsbane. The diameter is about 4 ~ 7 cm, the thickness is 0.5 ~ 3 cm, and occasionally it is as thick as 7 cm. The surface is yellowish brown or light brown. The plug skin is in the form of overlapping sheets, which is easy to peel off. The section is uneven, with obvious concentric rings alternating with dark brown and yellow and white, and occasionally the ring pattern is not obvious. Light weight, easy to break, flour-breaking, sticky when wet, and sticky when torn. Slight gas, sweet taste, and spicy.

Liaoning, Jilin, Heilongjiang, Inner Mongolia and Hebei.

The root characteristics of Euphorbia lunata are similar to those of the previous species, but the concentric ring pattern on the section is lighter, which is not as obvious as that of Euphorbia fischeriana. It is not sticky when wet with water.

Henan, Shandong, Jiangsu, Anhui, Hubei and other places.

The Stellera chamaejasme contained in Materia Medica is Stellera chamaejasme of Daphne family, so it should be regarded as authentic. However, the Stellera chamaejasme used in most areas at present is Stellera chamaejasme of Euphorbiaceae.

The root of Stellera chamaejasme contains sterols, phenolic components, amino acids, triterpenoids and toxic macromolecular organic acids. It may also contain anthracene glycoside.

Euphorbia fischeriana root contains resin 10.46% and1~ 2% hard rubber.

Pharmacological action A kind of chamaejasme glycoside was extracted from the root of Stellera chamaejasme, which was originally called antibacterial substance of chamaejasme chamaejasme toxin, and its toxicity was very low. Stellera chamaejasme decoction can increase the pain threshold of mice by 20 ~ 50% (electric shock mouse tail method and hot plate method) by gavage 6 g/kg. Anthracoside may be contained in leaves and roots, which can enhance intestinal peristalsis and treat constipation.

The root of Euphorbia fischeriana can be used to kill maggots. 20% decoction has little effect on respiration, blood pressure and isolated frog heart and intestine in anesthetized dogs.

Processing raw stellera chamaejasme: wash with water, moisten thoroughly, slice and dry. Stellera chamaejasme L. vinegar: Take Stellera chamaejasme L. tablets and mix well with vinegar, slightly stuffy. When the vinegar is exhausted, stir-fry them in a pot with slow fire until they are slightly dry, and then take them out and dry them. (every 100 kg of stellera chamaejasme tablets, 20 ~ 30 kg of rice vinegar)

The taste is bitter, flat and toxic.

① Classic: "pungent and flat."

② Bielu: "There is great poison."

③ Theory of Medicinal Properties: "Bitter and pungent in taste, toxic."

④ Ben Jing Feng Yuan: "Bitter and bitter, cold, great poison."

Return to the Meridian: "Start with Taiyin, and at the same time, reduce the points of Yin meridian and qi."

Indications: expelling water, eliminating phlegm, breaking accumulation and killing insects. Treat edema, abdominal distension, phlegm, food, insect accumulation, chest pain, chronic tracheitis, cough, asthma, tuberculosis of lymph nodes, skin, bone and epididymis, scabies, hemorrhoids and fistula.

① The Classic: "Cough against qi, breaking accumulation, diet, cold and heat, moisture, malignant ulcer, rat fistula, gangrene and poison."

② Bielu: "Treating hypochondriasis."

(3) The Theory of Medicinal Properties: "Treat phlegm and drink, and treat abdominal mass."

(4) Herbal Medicine in Southern Yunnan: "Treating the stomach for a long time, the diet is stuck, and the phlegm is thick and sticky. "attack insect accumulation, benefit waterways, relieve qi, eliminate edema and spit."

⑤ "Herbal Tongxuan": "Treating cough, treating insect gangrene, scrofula, phlegm and heartache."

⑥ "Handbook of Chinese Herbal Medicine Treatment in Plateau": "Purging qi to kill insects. Treat phlegm retention, periosteal inflammation, tuberculosis stubborn sore and alcoholic nose. "

Usage and dosage for oral administration: decoction, 3 ~ 8 points; Or into the pill, scattered. External use: grinding juice or grinding powder to apply.

It should be avoided that this product is toxic, and it should be taken carefully; Weakness and pregnant women should not take it.

① Notes on Materia Medica Classics: "Soybeans make it. Bad wheat and ginger. "

(2) Medicine Pair: "Wei Zhansi, a Buddhist monk."

(3) "Materia Medica": "If the spleen is insufficient and the qi is deficient in the day, it is not allowed to be used rashly."

④ "Deserve Materia Medica": "Fear of vinegar."

⑤ Manual of Chinese Herbal Medicine Treatment in Plateau: "Pregnant women should not use it, and chronic gastrointestinal ulcer should be used with caution."

Prescription ① Treatment of accumulation and abdominal distension as usual: four liang of Stellera chamaejasme (filed, fried with vinegar), three liang of Radix Aconiti Lateralis (cracked by blasting, peeled navel), and three liang of anti-sunflower. The medicine is smashed into powder, and the honey is refined and smashed for three or two hundred pestles. The pills are as big as buttonwood. Every time before eating, drink five pills with porridge to benefit. ("Sheng Hui Fang" Wolf Poison Pill)

(2) Those who treat the patient's heart disease and have qi stagnation under both sides: Stellera chamaejasme, Inula japonica, and Radix Aconiti Lateralis. Tamp the sieve, honey and pills are as big as a wuzi. Take two pills, slightly to three pills.

(3) Treatment of swelling and pain in the heart: two parts of wolfsbane and half of aconite. Sieve, honey pills are as big as wuzi. Take one pill a day, two pills on two days, three pills after three days, and three pills from one to three days.

(4) For treating yin hernia, the pill of yin shrinks into the abdomen, and the pain is dying: four ounces of wolfsbane, two ounces of Fangfeng, and three ounces of aconite (burning). Honey pills are as big as tung nuts. Take three pills, three times day and night. ((2) The following is "Filling the Back of Elbow")

⑤ Treatment of edema: fine powder of spurge, five points per share, boiled water. Avoid salt for 100 days, but diarrhea will remove yellow water, and its swelling will disappear by itself. If diarrhea persists, cold porridge will make it up. (southern Yunnan materia medica)

⑥ Treat all food accumulation, phlegm accumulation, insect accumulation, pneumatosis, lump pain, distension of chest, diaphragm, abdomen and abdomen, loss of appetite, yellow and thin face, and single abdominal distension: cotton spurge as the end and rice paste as pills. As big as a horse bean, take seven pills each time, and send them down in boiling water for the benefit. (southern Yunnan materia medica)

⑦ Treatment of tuberculosis of lymph nodes: For those who have not collapsed or have collapsed, Stellera chamaejasme is sliced, boiled with water, deslagging, taking liquid medicine, heating and concentrating into paste, cleaning the wound and applying externally. Second, those who have collapsed pull out pus: one catty of wolfsbane, eight points of snake slough, one or two peppers, and five dollars of rosin. Decoct radix Euphorbiae Fischerianae into paste, grinding other medicine into fine powder, sprinkling and stirring. External application Three healing lymph node tuberculosis wounds: one or two of stellera chamaejasme and one or two of dandelion roots. Decoct into paste for external application. (Selected Materials of New Medical Law of Chinese Herbal Medicine in Inner Mongolia)

⑧ Treatment of testicular tuberculosis: Stellera chamaejasme, Walnut and Alumen in equal amounts. Burnability, * * * ground into fine powder. Once a day, one yuan and three cents each time, with boiled water. (Selected Materials of New Medical Law of Chinese Herbal Medicine in Inner Mongolia)

⑨ Treatment of furuncle, wind and furuncle: Stellera chamaejasme, stir-frying in children's feces, and grinding. Take five minutes each morning and evening, with warm wine. ("Zhang Sanfeng Fairy Biography")

Attending to cure dry tinea scab, scratch the yellow water out, whenever it rains, it itches; Stellera chamaejasme is ground and coated with vinegar. ("Shenghuifang")

⑾ Treat scabies, ringworm and all boils for a long time: Stellera chamaejasme (stir-fry and grind into fine powder), and reduce Calomelas by half. Harmony, dry scabies and boils, scratch and rub them; Dry mixing for wet people has several effects. ("Yong lei zhong Fang")

⑿ Treat all the diseases in the viscera: take a large sum of money for the powder of Sichuan stellera chamaejasme, use a large amount of soap and a little sugar, assimilate it with water, and take it on an empty stomach when you are lying in bed, and take it off early tomorrow. ("Effective prescription")

[13] Treatment of traumatic bleeding: ground Euphorbia humilis is sprinkled on the wound. (Selected Chinese Herbal Medicine in Yunnan)

Clinical application ① Treatment of dermatosis

Cleaning Euphorbia lunata, peeling off the old skin, chopping, and decocting in water until it is twisted by hand into powder; Then filter with gauze, continue to decoct and concentrate the liquid medicine to a certain viscosity, and apply it to the affected part after cooling, once a day or every other day/kloc-0. Or made into tablets, each tablet contains 0. 1 8g of crude drug, and is taken orally before going to bed for the first 5 days, and 1 tablet in the morning and evening of the 6th ~ 1 0 day, and then increased to1tablet in the morning, afternoon and evening, with a course of treatment of 20 ~ 30. 30 cases of psoriasis were treated with the above thick paste, 13 cases were cured, 16 cases were improved, 1 case was ineffective; 22 cases of psoriasis were treated with tablets, 2 cases were basically cured, significantly improved 1 1 case, 7 cases were improved, and 2 cases were ineffective. Thick ointment is also used to treat neurodermatitis and chronic eczema 15 cases, all of which have good curative effects. Generally, it can be effective after being applied for 3 ~10 times. This product is toxic. Oral tablets have gastrointestinal disorders (such as decreased appetite, nausea, bowel sounds, diarrhea, abdominal pain, etc.), dizziness, pain, fatigue, weight loss and other reactions. Except for 1 case who stopped treatment because of frequent diarrhea, the rest cases stopped taking medicine or reduced the dosage, and all of them got better on their own. In addition, it was found that the number of white blood cells and platelets in some patients decreased slightly after treatment, and they all returned to normal after application of vitamin B4 or B6.

② Treatment of tuberculosis

Firstly, the date of Stellera chamaejasme is made, which is prepared by putting Stellera chamaejasme in a pot, decocting with water, and steaming the date in a steamer for about two and a half hours. Stellera chamaejasme and jujube were prepared in a ratio of 2: 4. Adults should take Stellera chamaejasme three times a day, each time 10 capsules, and gradually increase or decrease depending on the side effects, with a maximum of 20 capsules each time; Or130g (about 30 capsules) per day for the first week, 225g (about 45 capsules) per day for the second week, and 300g (about 60 capsules) per day after the third week, which is taken orally for three months. The interval is1~ 2 weeks, and the second course of treatment can be given according to the situation. It has been used to treat lymph node tuberculosis, bone tuberculosis, skin tuberculosis, epididymal tuberculosis, tuberculous keratitis and pulmonary tuberculosis, and all of them have certain curative effects. Of the 30 cases of pulmonary tuberculosis, symptoms improved in 22 cases, weight increased by 2-23 Jin in 28 cases, lesions progressed 18 cases, sputum bacteria turned negative in 9 cases, erythrocyte sedimentation rate decreased 14 cases, and the deterioration was only 1 case. For other extrapulmonary tuberculosis, whoever can take it patiently has different curative effects. Side effects include nausea, dizziness and loose stool. It disappears after reduction or withdrawal. In addition, the wolf venom left in the pot after steaming the dates of Euphorbia fischeriana is filtered and concentrated into a thin paste paste with slow fire, which can be used as a local therapeutic agent to treat skin tuberculosis, tinea scabies, various concealed dermatitis, alcoholic nose, alopecia and various intractable ulcers, etc., and has certain effects.

③ Treatment of tumor

Take Stellera chamaejasme 1 Money, boil it in 200ml water, then take it out, then add 2 eggs and cook them, then eat them and have soup. It was used to treat 25 cases of gastric cancer, liver cancer, lung cancer and thyroid adenocarcinoma. After treatment, the symptoms were relieved, and the tumor shrank in a few cases. You can also make compound Stellera chamaejasme injection with Spatholobus suberectus, Coicis Semen, Scutellariae Barbatae, etc., 20 ~ 40ml each time, and add 5% glucose solution for intravenous drip. Or made into compound stellera chamaejasme tablet for oral administration. In the treatment of 20 cases of advanced gastric cancer, preoperative medication can relieve symptoms and create conditions for surgical treatment; Taking medicine after operation can consolidate the curative effect and stabilize the condition. After taking the medicine, it generally has the functions of relieving pain and stimulating appetite. The common side effects were nausea, vomiting, dizziness and mild diarrhea, and no toxic manifestations were found in liver, kidney and nerve.

④ Treating chronic tracheitis.

Take Euphorbia fischeriana and make it into decoction or pill, each dose is equivalent to 0.5g of dry product, three times a day, and take it after meals. 299 cases were treated and observed for 10 day, with 52 cases (17.39%) being markedly effective and 70 cases (56.86%) being improved. It has good antiasthmatic, expectorant, antitussive and anti-inflammatory effects, especially the antiasthmatic effect; After taking the medicine 1 and 2 days, most of them consciously vented their breath and saved energy, and the sputum was easy to cough up. After 5 days, the number of coughs and the amount of sputum decreased, and their appetite increased obviously. However, the side effects are great. After taking the aqua for 30 minutes, the patient will have stomach discomfort, numbness in the mouth and pharynx, dizziness and nausea, or diarrhea and abdominal pain, and will get better by himself after stopping taking the aqua for 3-24 hours. Pills all have diarrhea symptoms, and are not suitable for those who suffer from prolonged heat, dry throat and tongue, hoarseness, vomiting and nausea. The above-mentioned Euphorbia fischeriana dates can also be used to treat this disease, taking 3 ~ 5 tablets each time, three times a day, and the side effects are obviously reduced compared with those of water or pills. 278 cases were observed 1 month, 2 cases were basically cured, accounting for 7.6%, and 9 cases were markedly effective11month, accounting for 42.8%. Only a few cases had slight dry mouth and very few cases had slight changes in liver function.

Famous experts discuss "Ben Jing Feng Yuan": "Stellera chamaejasme is a great poison, not a constant product. "Ben Jing is mainly used to cough against the upper qi, but it is suitable for those who cough violently with strong qi."

Remind you: Stellera chamaejasme, a Chinese herbal medicine, comes from the Internet. Please follow the doctor's advice before using it.