Total bile acids (TBA) are bound bile acids synthesized by the liver and bound with glycine or taurine. The normal value of TBA in pregnant women with normal liver function is 0 ~ 10μ mol/L, and the content of serum bile acid in healthy people is very small. When hepatocytes are damaged or blocked inside and outside the liver, bile acid metabolism will be abnormal and total bile acid will increase. The high total bile acid in pregnant women is caused by abnormal bile acid metabolism and hormone level changes during pregnancy. Pregnant women with high bile acid are prone to intrahepatic cholestasis.
The normal value of total bile acid in normal people is 0 ~ 10μ mol/L, so what is the normal value of total bile acid in pregnant women? Generally speaking, the normal value of total bile acid of pregnant women is 1- 12 μ mol/L, so remind pregnant women whose total bile acid is higher than 12 to go to a regular hospital for examination as soon as possible, so as to find the disease and treat it as soon as possible!
The total bile acids in human serum are synthesized and decomposed by the liver, thus maintaining the relative stability of human bile acids. The determination of total bile acids is one of the more sensitive and effective liver function tests. When liver cells have pathological changes or bile duct diseases, it can cause bile metabolism disorder and significantly increase the content of bile acids entering the blood.
Bile is synthesized in the liver and usually flows to the small intestine through the bile duct. Bile can help the small intestine digest food. If you suffer from obstetric cholestasis, the bile flowing to the small intestine will decrease, which will lead to the accumulation of bile salts in your blood.
The main symptom of obstetrical cholestasis is itchy skin, which will be more serious at night, causing fatigue and insomnia. Itching usually starts from the palms and soles of the feet, and then it may spread all over the body. Some pregnant women can't stand itching, so they keep scratching and even scratch their skin. A few sick pregnant women will have jaundice. Within a week or two after delivery, itching symptoms will completely disappear.