puffer fish is forbidden to be sold in the market, because puffer fish is poisonous. Once people eat it by mistake, they usually get sick half an hour to three hours after eating. At first, they have stomach discomfort, nausea, vomiting, abdominal pain, diarrhea, and even bloody stool, accompanied by general malaise, numbness of the lips, tip of the tongue and fingers, numbness of the whole body, weakness of limbs, drooping eyelids, difficulty in walking, muscle weakness, decreased or disappeared pain and tendon reflex, shallow and irregular breathing, followed by difficulty breathing and cyanosis.

The testicles or ovaries, skin, liver and roe of puffer fish are highly toxic, and the toxicity is the strongest during the reproductive period at the turn of winter and spring. Its toxic components are mainly tetrodotoxin and tetrodotoxin, which act on the nervous system of human body, making the conduction of nerve endings and nerve centers obstacle, and finally paralyzing the respiratory and circulatory center of brain stem, leading to death.

In case of puffer fish poisoning, we should race against time to rush to the hospital for active rescue, and induce vomiting, gastric lavage, intestinal lavage, infusion and artificial respiration as soon as possible.

But I have read a novel "Puffer Fish" written by He Manzi, in which a family committed suicide by eating puffer fish. They started cooking in the morning and didn't eat together until their father came back in the evening, but the toxicity disappeared because it took too long to cook. . .