Povidone iodine
Povidone iodine
English name: Alec, Etsujing, povidone iodine, pyrrolidone acid, polyvinylpyrrolidone iodine.
Povidone iodine is brown amorphous powder, slightly smelly, and its aqueous solution is acidic. Soluble in water and ethanol, insoluble in ether, chloroform, acetone, ethane and carbon tetrachloride, melting point: 300℃. The aqueous solution has no shortcomings of iodine, light color, easy elution, little irritation to mucosa, no need to use ethanol to remove iodine, no corrosion and low toxicity ... Our products are divided into two grades:
Third, product indicators.
Technical specification of products
Technical grade PVP iodine powder
Medical povidone iodine powder
air shrinkage
≤8.0%
9.0~ 12.0%
Available iodine
9.0~ 12.0%
≤8.0%
nitrogen content
9.5~ 1 1.5%
9.5~ 1 1.5%
ignition residue
neglect
≤0. 1%
Fourth, application
1, used in industrial and agricultural production:
PVP- iodine precipitates iodine in water, which can be gradually interpreted and released, thus playing the role of disinfection and killing microorganisms. It has high-efficiency and broad-spectrum bactericidal effect, and has strong bactericidal ability and disinfection effect on bacteria, fungi and viruses.
Different concentrations of polyvinylpyrrolidone iodine solution have different effects on bacteria, such as: 50mg/L effective iodine can kill Escherichia coli, Pseudomonas aeruginosa and Staphylococcus aureus in 8 minutes; 200ms/L available iodine can destroy HBsAg for 30 minutes and inactivate poliovirus 15 minutes. 1000mg/L available iodine can kill bacterial spores for more than 2 hours; 20mg/L of available iodine 1 min can kill 90% of Aspergillus Niger spores.
PVP- iodine is mainly used in food industry and aquaculture for sterilization and prevention of animal diseases. Suitable for disinfection of foot-and-mouth disease and wounds in horses, cattle and pigs.
Prevention and treatment of bacterial and viral diseases of aquatic animals: eels: red phosphorus, rotten gills, rotten tails, aquatic bacteria, gill diseases caused by low water temperature, gill diseases caused by viruses and diseases caused by trauma. Shrimp: rotten cheeks, black cheeks, yellow cheeks, broken whiskers and stuck. Turtle: Skin ulceration, white spots and erythema. Frog: Skin disease, erythema.
2. Pharmaceutical industry:
Povidone iodine has the bactericidal effect of iodine, but the effect is stronger. Povidone iodine is used as disinfectant in medicine, and as inhibitor in antisepsis of eye drops, nose drops, creams and other preparations. The disinfectant can be used for disinfection of pharmaceutical utensils and packaging.
Povidone iodine is used for skin disinfection and instrument disinfection such as hospital surgery and injection; Prevention of oral, gynecological, surgical and dermatological infections; Sterilization and disinfection of household tableware and utensils; It is often made into 5% ~ 10% aqueous solution, tincture, aerosol, cream, suppository, etc.
Povidone iodine itself has only a small physical and chemical activity, and there is no incompatibility with other drugs. It has a strong killing ability and a very reliable disinfection effect on bacterial spores, fungi and viruses.
Povidone iodine is the first choice of iodine-containing medical bactericide and disinfectant for health and epidemic prevention in developed countries. It is used as a disinfectant in medicine and as an inhibitor of preservatives in eye drops, nose drops, creams and other preparations. The disinfectant can be used for disinfecting pharmaceutical instruments and packaging. The concentration is usually 5- 15%, which has been included in China Pharmacopoeia in 2000.