There are many reasons for the increase of uric acid, because there is a lack of uricase in the human body, and the final metabolite of purine is uric acid. To reduce the uric acid content in the body, we must mainly start with purine, and the reasons for the increase of purine content in the body are summarized as follows:
1, excessive intake of exogenous purine
Seafood, animal offal, meat, beer, etc. are all foods with high purine content, and the uric acid content is directly proportional to the purine content in food. Eating too much will lead to an increase in purine content in the body.
2. Excessive endogenous purine production.
Endogenous purine production is an important way to produce purine in vivo, mainly through the oxidative decomposition of nucleic acid, and the abnormality of related metabolic enzymes in the metabolic process will lead to excessive purine synthesis.
3. Increased purine metabolism
Some diseases often lead to increased purine metabolism, such as rhabdomyolysis, polycythemia, myeloproliferative diseases and so on, as well as high uric acid during chemotherapy or radiotherapy.
4, uric acid excretion disorder
Uric acid is mainly excreted through the kidney. If renal vascular disease will lead to uric acid excretion disorder, it will cause hyperuricemia.
1, reduce purine intake in vitro
Give priority to corn, white bread, steamed bread, noodles and soda biscuits; Cabbage, carrot, celery, cucumber, eggplant, cabbage, lettuce, pumpkin and other vegetables; All kinds of eggs, milk, condensed milk, fruits, dried fruits, sweets and other foods with little or no purine content.
2, reduce the metabolism of purine in the body.
Long-term use of foods containing anthocyanins and other anti-nucleic acid oxidation components, such as purple cabbage and carrots, can reduce the production of endogenous purines by 80%.
3, accelerate the excretion of uric acid in the body.
Eat alkaline foods such as apples, pears and other fruits, as well as vegetables such as rape, cabbage and kohlrabi, or drink sour tea to moderately alkalize urine to promote uric acid excretion.