1 anti-space motion sickness drugs, space motion sickness is a common disease in space activities, with high incidence and wide spread. Taking drugs for space motion sickness has a certain effect on restraining and alleviating the symptoms of motion sickness. Such drugs include anticholinergics and antihistamines. In the early space flight, American astronauts took antihistamines such as oxazine and Tegan, and later studied scopolamine and phenylephrine. Taking it alone is not as effective as the compound prescription. In addition to oral administration, there is also an adhesive plaster with ointment, which can be attached to the skin of the head and achieve therapeutic effect through skin absorption. 2 anti-radiation drugs, astronauts flying in space, there are two aspects of space radiation danger. One is the radiation source of space particles, and the other is the artificial radiation source. These commonly used drugs include sulfab, sulfadiazine and amino2-isothiourea, which have certain protective effects on high-energy atoms and can be used together with vitamins. 3 Anti-decalcification drugs, under the influence of weightlessness, the discharge of inorganic salts such as calcium, phosphorus and magnesium in urine increases, and the consequences of a large number of decalcification may be due to severe osteoporosis after returning to earth, in order to prevent decalcification, besides proper "body therapy" and "diet therapy", "drug therapy" is also an important preventive measure. These drugs include calcium phosphate preparations. The loss of bone calcium in astronauts taking such drugs is significantly lower than that in astronauts not taking drugs. 4. Sleep-regulating drugs, including some sedatives and hypnotics, are provided to astronauts to regulate sleep. These drugs should take effect quickly after taking, and the efficacy will disappear quickly after waking up, and there should be no side effects such as drowsiness and listlessness. 5 Drugs to improve work ability, people working in the spaceship environment have to withstand the test of many special environments, and people's sensory function, motor function and brain center function will be fatigued due to this environment, which will have an impact on work. Especially in long-term space flight, this kind of fatigue will appear periodic cycle, and taking some drugs to improve work ability can eliminate fatigue. This kind of drugs include powerful stimulants such as amphetamine, as well as nonspecific drugs such as ginseng, acanthopanax senticosus and blush days. It has a certain promoting effect on improving work efficiency and stabilizing work mood. Therefore, astronauts should take some drugs to promote their work and enhance their activity energy even if they are disease-free during space flight, otherwise, once fatigue attacks, their work will be distracted and bring bad consequences. The medicine box in the spaceship is not completely set for diseases, but also for rest and work. There are dozens of kinds of medicines. Here, the medicines in the medicine box in the cockpit of the Apollo spacecraft in the United States are listed, which shows the situation of astronauts taking medicines.