Other names of Tuyuan: ground beetle, soil beetle, crossing the street, ground turtle, joint bug, bed bug mother, ground beetle. They are insects with flat bodies and brown-black bodies. The males have wings and the females have no wings. Often active in the soil at the base of residential walls.

Effects and functions of Tuyuan:

1. Anticoagulant and fibrinolytic effects

The ground beetle has an anticoagulant effect and can improve And enhance the blood supply of major organs, tissues and whole body in the body. The water extract of ground beetle was given to rats by gavage for 7 consecutive days, which can significantly prolong the bleeding time and recalcification time of rats. It also has a significant inhibitory effect on the aggregation rate of platelets and can significantly inhibit external sources. The aggregation-inducing effect of ADP and the release function of platelets. It can also shorten the electrophoresis time of red blood cells, suggesting that the drug can increase the surface charge of red blood cells in blood circulation.

2. Effect on heart pump function

When the total alkaloids of the soil beetle are injected intravenously into rabbits (5mg/kg, 10mg/kg, 15mg/kg, 20mg/kg) , showed obvious negative effects on the rabbit heart, that is, left ventricular systolic pressure, left ventricular end-diastolic pressure, and left ventricular pressure maximum rate were all reduced,

right atrial pressure increased, electrocardiogram P-R conduction and heart rate Weakened, mild ischemic changes in S-T segment. When 20 mg/kg or more is used, obvious S-T segment ischemic changes appear on the electrocardiogram, as well as premature ventricular contractions.

3. Anti-tumor effect

The beetle has a certain inhibitory effect on tumors in experimental animals. In vitro experimental results show that the beetle can inhibit the respiration of liver cancer and gastric cancer cells. In the test tube, the Melanide method was used to determine that the beetle extract had the effect of inhibiting the white blood cells of leukemia patients, but the results were negative using the Waver respirator method.

4. Effect on tissue hypoxia

The water extract of ground beetle can significantly reduce the oxygen consumption of cultured neonatal rat cardiomyocytes. The total alkaloids of the ground beetle can prolong the disappearance time of the ECG in mice, prolong the survival time of mice suffering from hypoxia due to increased oxygen consumption, and can resist ST-T changes caused by acute myocardial ischemia in rats. These effects may be related to improving the tolerance of the myocardium and brain to ischemia and reducing the oxygen consumption of the heart and brain tissues.

5. Other effects

The "tuberculosis powder" made by mixing ground beetles with whole scorpions and centipedes has no antibacterial effect on human Mycobacterium tuberculosis in the test tube. The water beetle decoction can make the plasma (HDL-C/TC) ratio of quail with experimental hyperlipidemia significantly higher than that of the induced group, and has a certain effect in regulating blood lipids.

Baidu Encyclopedia—Turtle