1) If the mother is a homozygous patient (XX has a disease gene) and the father is normal, the son must carry the disease gene, and the daughter has a 50% chance to carry the gene.
2) If the father is a patient (X disease gene), the mother is normal, the son must be normal, and the daughter must carry the gene.
3) If the mother is heterozygote (only X has the sick gene) and the father is normal, the son has a 50% chance of getting sick and a 50% chance of being normal; Daughters have a 50% chance of carrying the gene.
So, to answer your question. We must know the sex of the child. If it's a boy and his father doesn't have this disease, it's absolutely impossible to pass it on to him by his father, only by his mother; If it is a girl, it is inherited by both parents at the same time.
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