1. Causes general liver damage: long-term or excessive consumption of ginger pinellia, puhuang, locust, mountain arrowroot, etc. may cause discomfort, pain, and abnormal liver function in the liver area.
2. Causes toxic liver damage: Excessive consumption of too much decoction of too many seeds, too many seeds, too many seeds, such as too many seeds, too much decoction of too many seeds, such as too much decoction of too much decoction of too much decoction of too much decoction can cause toxic hepatitis.
3. Hepatopathic jaundice: Long-term use of rhubarb or intravenous infusion of Sijiqing injection will interfere with the bilirubin metabolism pathway and cause jaundice.
4. Induce liver tumors: Chinese herbal medicines such as Schizonepeta, Acorus, star anise, Zanthoxylum bungeanum, beehead tea, Senecio, etc. contain sassafras; agarwood, Akebia, saltpeter, cinnabar, etc. contain nitrate base compounds can induce liver cancer.
With the increasing use of drugs, a series of adverse reactions occur frequently, among which the damage to the liver caused by drugs is the most serious. It is mainly reflected in three aspects: the occurrence of liver cell inflammation, abnormal increase in transaminases and damage to liver cells.
Liver-protecting tablets are made of 6 medicinal materials including Schisandra chinensis, Bupleurum chinensis, Yincheng, isatis root, pig gall powder, and mung beans. It has obvious effects on liver cell damage caused by various drugs. It is an auxiliary hepatoprotective drug for chronic diseases such as tuberculosis, tumors, chemotherapy, cardiovascular and cerebrovascular diseases, mental diseases, hyperthyroidism, epilepsy, diabetes and other chronic diseases that often cause liver cell damage. , is one of the most commonly used liver-protecting drugs in clinical practice. Hugan Tablets can significantly improve the clinical symptoms of DILD patients, has a strong ability to repair damaged liver cells, reduce serum aminotransferases, induce liver enzyme activity, and reduce drug damage to liver cells; the main drug Schisandra chinensis (containing Schisandrin B) The induction of liver mitochondrial cytochrome P450 is very critical.
In the prescription, Schisandra chinensis astringes and fixes astringency, replenishes qi and promotes body fluids; Bupleurum and wormwood soothes the liver and relieves stagnation, clears away heat and promotes dampness; isatis root, pig gall powder, and mung bean clear away heat and detoxify. The combined use of various medicines has the effects of soothing the liver and relieving stagnation, clearing away heat and nourishing the liver, diluting dampness and detoxifying. Pharmacological studies have shown that: Schisandrin B in Schisandra chinensis has a significant effect in reducing ALT, can significantly promote the incorporation of 14C-phenylalanine into liver proteins, increase the content of hepatocyte microsomal cytochrome P-450 and protein, and induce medicinal enzymes, thus It exerts anti-liver damage and detoxification effects. The principle of Bupleurum against liver damage is related to its anti-inflammatory effect, promoting the assimilation of liver proteins, increasing liver glycogen, improving hyperlipidemia and fatty liver, etc. The saikosaponin in Bupleurum has a direct protective effect on cell membranes, and it can It increases the smooth endoplasmic reticulum of liver cells and enhances enzyme activity, which is beneficial to the metabolism of poisons. At the same time, it also stabilizes liver cell organelle membranes, especially the protoplasmic membrane, microsomal membrane and mitochondrial membrane, and promotes liver cell regeneration. . Artemisia arborescens can significantly resist the damage caused by carbon tetrachloride, increase liver cell activity, decrease ALT content, and have a hepatoprotective effect. The alcohol extract of Artemisia arborescens has a significant inhibitory effect on liver cell damage. Isatis root is a commonly used medicine for acute hepatitis, which can quickly eliminate symptoms and promote the recovery of liver function. Pig gallbladder is effective in improving the symptoms of infectious hepatitis, subsides jaundice, hepatomegaly and restores liver function. Mung beans can relieve alcohol and food poisons.