The maximum dose depends on the condition, but it is not certain. Reference: To talk about the toxic reaction of clinical application of aconite, we must correctly understand the clinical dosage of aconite. Opinions are divided on this issue. Some scholars advocate the extensive use of Radix Aconiti Lateralis in clinic, while others oppose the former opinion by using Radix Aconiti Lateralis in clinical or scientific experiments. It is difficult to draw a conclusion now, and it will be difficult to reach a unified opinion in the future. I have served my uncle and watched him all my life. People in central Henan are known as the doctor of aconite, and it is not uncommon to use five or six doses of aconite every day. Most people use nine or twelve doses of aconite every day, and many people use more than ten kilograms of aconite. According to clinical experience, aconite root can only be used for chronic diseases such as cold and dampness, drinking, such as general numbness, abdominal sound, diarrhea, etc., in order to receive special effects.
The following materials are quoted:
Dose regularity and body manifestations of Aconitum carmichaeli
Yin cold is extremely heavy, forcing yang to go out, and aconite can't be saved without a large dose. If the weather is cold and humid, don't give large doses suddenly. Rome wasn't built in a day, so come slowly. On the premise that there is no difference between the prescription and the prescription, start with three or five yuan a day, add five yuan for every two doses, and then take it for three or four days according to the original dose until the prescribed poisoning symptoms are taken, and then reduce five yuan a day; Reduce it to one or two, and it will basically heal. Do a good job in the aftermath and consolidate the curative effect. Other ministers and ministers in the party may increase losses as appropriate. If the patient has a fever or seems to have a fever at that time, you can add Hangzhou Shao to count the money, but the amount of aconite is generally not reduced. The dosage of aconite is generally San Qian (traditional Chinese medicine), and its clinical use ranges from 562 to 120. The author thinks that there is no need to stipulate the maximum dosage of aconite, and it should be given according to people's symptoms. Medicine tries disease, medicine does not take responsibility, medicine sends disease, and poison wins pills.
Generally speaking, the physical reaction of taking a large amount of aconite is not obvious in the first ten days, but later when the dosage is large, the patient begins to feel numb in the mouth and lips, and then the whole body is numb, snoring, abdominal rolling, accompanied by diarrhea, and the discharge is mostly white frozen mucus, without abdominal pain and fall. At this time, the patient consciously releases the cold in the abdomen. In severe cases, the mouth can't speak and the limbs can't move (at this time, the patient has no symptoms such as sweating and asthma, and his heart is clear). This is a struggle between medicine and disease. When chronic diseases are eradicated, don't be afraid to worry, and don't use drugs to detoxify. After about two hours, the symptoms of numbness and dizziness gradually disappear, and the dose will not be increased at this time. If you are not brave enough, the dose will not reach this level. Although the medicine is symptomatic, it is difficult to take effect quickly. If the drug is stopped due to local poisoning (numbness of mouth and tongue, abdominal sound and diarrhea), the original dose must be taken continuously for about ten days, and then the dose of aconite is reduced after the abdominal cold accumulation is completely eliminated.