High blood pressure refers to the body's blood pressure value is significantly higher than normal. Although as a chronic disease, high blood pressure does not cause direct harm to the body, but will threaten the patient's own health, indirectly leading to other organs of the body damage, jeopardizing the health .
Currently, the number of patients with hypertension and diabetes in China is increasing year by year, but there is no specific drug to completely eradicate it, especially hypertension, the number of patients in China has reached 400 million, once the confirmation of hypertension, which means that the need for life-long medication. Hypertension is especially scary for older people and can lead to many complications.
High blood pressure refers to the human body systolic blood pressure 140 mm Hg, diastolic blood pressure 90 mm Hg as the main feature , accompanied by heart, kidney, brain and other organs damage to the clinical features. Hypertension is one of the more common forms of chronic disease, and it is also the most important cause of cardiovascular and cerebrovascular disease.
Typically, blood pressure fluctuates within a certain range with changes in the surrounding environment, and shows a gradual increase in blood pressure with age, with systolic blood pressure being the most pronounced.
Hypertension can be categorized as primary or secondary, and the cause of primary hypertension remains unclear. In 5% of patients with hypertension, it is caused by one or more specific diseases, which is called secondary hypertension. Secondary hypertension can be treated by treating the specific disease(s) that are responsible for the high blood pressure.
Since the cause of hypertension is not clear, bad habits, heredity, etc. can lead to hypertension. According to incomplete statistics, a large portion of the occurrence of hypertension and the patient's own bad habits are closely related, then what bad habits will lead to the occurrence of hypertension?
1, excessive obesity
Often, the patient is caused by obesity and high blood pressure, through the way to lose weight to control the blood pressure rise.
Thus, if you have excessive obesity hypertension patients, you must lose weight in a timely manner, as long as the weight control within a reasonable range, in order to control the blood pressure.
2, genetic
Many studies have shown that hypertension is a polygenic genetic disease. After analyzing the research, we know that if both parents suffer from hypertension, the chance of their children suffering from hypertension in the future is as high as 45%. If one parent is hypertensive, the probability of the child developing hypertension in the future is 28%. However, when both parents are normal, the probability that the child will have high blood pressure in the future is only 3%.
3, too much taste
Salt is the main ingredient of sodium chloride , if the body intake of salt, the body will be due to the accumulation of sodium chloride in the body, affecting the intra- and extracellular osmotic pressure , resulting in the emergence of High blood pressure. This is because, when the body intake of excess salt, but also stimulate the body of renin - angiotensin, so that the blood vessels produce abnormal contraction, resulting in increased pressure on the blood vessel wall
4, excessive pressure
At present, the pace of life is too fast, especially young people work pressure, life stress, payroll The first thing you need to do is to get a good deal of money, and then you have to pay for the money.
In the high-intensity mental stress, there will be insomnia, depression and other symptoms, the long run is very easy to induce high blood pressure .
5, do not love sports
A study shows that proper exercise can effectively promote blood circulation, reduce the human blood vessels deposited lipids , to avoid the accumulation of fat.
6, lack of calcium
The human body if the lack of calcium, will also lead to high blood pressure. Hard water contains more calcium and magnesium ions, these elements can effectively regulate the human blood vessels within the smooth muscle cells, if the lack of, the human body will be prone to spasms, ultimately leading to the occurrence of hypertension. Thus, in our daily life, we should drink more water rich in calcium and magnesium ions to supplement calcium.
At the same time, our diet should be diversified, and eat more calcium-rich foods in our daily life, such as dried beans, fish, tofu, dark-colored vegetables such as cauliflower, kale vegetables, and kale and other foods. Especially middle-aged and elderly people, who are losing calcium in their bodies as they age, need to pay particular attention to calcium supplementation.
Previously, due to limited medical care, the treatment of hypertensive patients only started with how to lower the patient's blood pressure, and although the patient's blood pressure was lowered, it was accompanied by other side effects. In particular, the three antihypertensive medications, Compound Robitussin Tablets, Compound Antihypertensive Drugs, and nifedipine, have particularly large side effects.
With the continuous improvement of medical treatment, many antihypertensive drugs with fewer side effects are now on the market, and fewer and fewer people are taking these three antihypertensive drugs. But there are still a lot of patients are not clear, still taking these three drugs, so these antihypertensive drugs in the end will bring what side effects?
1, compound rosmarinus officinalis tablets: Compound rosmarinus officinalis tablets for hypertensive patients, is a very common drug. This is a kind of medicine made through the combination of Chinese and Western medicine, the main ingredients for isoprinosine hydrochloride, wild chrysanthemum, bishydralazine sulfate and rosmarinus officinalis leaves .
Isoprinosine hydrochloride and dihydralazine sulfate are two ingredients that have a strong effect on the human body, reducing sympathetic excitability and speeding up the blood flow, resulting in a rapid heart rate and panic attacks.
At the same time, long-term use of the drug, but also cause stomach pain stomach pain , diarrhea and other adverse reactions, reduce the body's immune system . Although the effect of lowering blood pressure is good, but the human body is more harmful, at present, basically has been eliminated.
2, nifedipine: as one of the current recommended drugs for the treatment of hypertension, nifedipine has a shorter duration of efficacy, and the effect is not stable .
Blood pressure is affected by more factors, after taking the drug, sometimes the effect may be better, sometimes the effect may be very unsatisfactory, especially unstable, especially for the elderly, more uncertain factors, this less stable antihypertensive drugs, sometimes not only can not play a role in lowering the effect of blood pressure, but also to the elderly will cause harm.
3, the compound antihypertensive drugs: this antihypertensive drugs is the biggest feature is the cost-effective . In the case of lower prices can also guarantee the effect of antihypertensive, and therefore by many older people's favorite. However, this kind of antihypertensive drug has a component of the drug for the blood pressure, this kind of drug will also affect the sympathetic nerves of the person, the side effects are larger.
After taking the drug, patients will experience drowsiness, fatigue and other symptoms, which may lead to depression after a long time. And this drug is also more harmful to the human kidneys, and can cause other complications, has been phased out.
In the face of increasing numbers of hypertensive patients, it has become increasingly important to control blood pressure and effectively reduce complications. As a result, three new types of antihypertensive drugs have emerged, with better antihypertensive effects and fewer side effects.
1, Benidipine
Benidipine as a new type of dihydropyridine calcium antagonist, calcium channels in the three channels have a certain blocking effect. And it is 14 times more selective to blood vessels than nifedipine, which can ensure the antihypertensive effect well. In addition, Benidipine is also highly selective for some important arterial vessels in the human body.
Benidipine's antihypertensive effect is obvious, the mode of action is gentle, can treat kidney damage caused by hypertension, but also can be used for non-hypertensive and other chronic kidney disease damage to the kidneys, play a role in protecting the kidneys, reduce proteinuria the role of . As a result, this drug is particularly effective in the treatment of senile hypertension.
It has been shown that the blood concentration of the drug can be reduced to zero after 7 hours of administration, and although its half-life in plasma is only about 60 minutes, the hypotensive effect lasts for a day.
2, Alisatan Lipids
Alisatan Lipids can be absorbed by the human body in the intestinal tract, by the esterase effect of the complete hydrolysis, into a pharmacologically active metabolite. This product binds to the tensin in the body's blood vessels, ultimately lowering blood pressure.
The drug is not directly metabolized by the liver, which effectively reduces the impact of the drug components on the liver and reduces risk. When the drug is metabolized, it does not produce other unrelated products, which not only reduces blood pressure, but also reduces side effects, which is safer for patients.
Alisatan ester is mainly used in the treatment of moderate to mild hypertension, and only need to take the drug once a day, for patients, more convenient. However, it is not recommended to take food at the same time as it reduces the absorption of alisatan ester during the medication.
3. Sacubitril valsartan
Previously, sacubitril valsartan was the main drug used in the treatment of chronic heart failure, and it can largely reduce the risk of cardiovascular death as well as heart failure in patients.
As research on the drug has progressed, it has been found that it works better and smoother than traditional antihypertensive medications, especially at night. In addition, sacubitril valsartan is also effective in treating and preventing some of the complications of hypertension, such as coronary heart disease, chronic kidney disease, and other complications.
Taking antihypertensive drugs also have to pay attention to, using the wrong way to take, not only can not control blood pressure, but also counterproductive.
Taking medication according to the temperature: Human blood pressure changes with the seasons and temperature. In the change of season, when the weather is cold, antihypertensive drugs should be increased in the appropriate amount of medication.
In the fall and summer, some antihypertensive drugs can be reduced. It is also important to pay attention to the daytime and nighttime, as blood pressure usually decreases at night and rises slightly during the day. When adjusting the dosage of medication, try to choose the time before the peak blood pressure comes, to have the most significant effect.
Take the drug according to the characteristics: In the process of taking antihypertensive drugs, according to the characteristics of the drug itself. Currently, many antihypertensive drugs can be taken for a long time, and can be eaten 1-2 times in 24 hours, so they should be taken regularly and quantitatively. With the continuous progress of medical care, the half-life of the drug is gradually increasing, and can be effective for a long time, sometimes 1-2 times a week to eat to achieve the effect of the drug.
Take from the smallest dose: In the treatment of hypertension, start with the smallest dose, which can effectively reduce some of the problems caused by the strength of the drug. After 7 days of medication, if the patient's blood pressure still does not appear to be significantly reduced, it may be that the drug is not effective for the patient, at this time, you can replace the other drugs.
If the blood pressure has remained stable for some time afterward, the dosage of the second medication should be gradually reduced until the blood pressure level and the "minimum dose" of medication remain at the desired level. This "minimum dose" of medication is also known as the maintenance dose.
As the quality of life continues to improve, it is important that people enjoy their lives, but at the same time, they are disciplined to ensure a healthy lifestyle and diet. Currently, the number of patients with hypertension is increasing year by year, and the age of the disease is getting younger and younger, hypertension is no longer just a nightmare for the elderly, but now there is a tendency of globalization and spread.
For patients who already have hypertension, it is important to keep abreast of the new generation of antihypertensive drugs, and choose the right antihypertensive drugs for their health condition, so that they can better treat hypertension.