Lego, a pesticide, pure white needle-like crystals, solubility in water 39 g / liter (room temperature). It is readily absorbed and transported throughout the plant. Chemical name O, O-dimethyl-S-(N-methylcarbamoylmethyl) dithiophosphate. 1951 American E.I. Hoberg and J.T. Cassady found that there is an insecticidal effect, the United States in 1956 to develop and promote the enterprise. It can also be used to kill mites.
Emergency medical care
Diagnostic points:
(1) Long incubation period. Sometimes coma may appear 2~4 h after oral administration.
(2) Long course of the disease. Due to the slow excretion of leucovorin in the body, easy reabsorption and long recovery period of blood cholinesterase activity.
(3) easy to repeat. The recurrence rate of the poisoning of this product is significantly higher than that of other organophosphorus species poisoning. Acute poisoning after 3-5 d, in the case of the condition has been basically relieved will be sudden rebound, resulting in sudden death.
(4) A series of manifestations of cholinergic nerve over-excitation.
(5) A small number of patients with acute poisoning 1~4 d after the intermediate phase of muscle weakness syndrome, severe respiratory distress due to respiratory muscle paralysis, or even death.
(6) The incidence of toxic myocardial damage is high. Due to the accumulation of Lekomat and its impurities in the myocardium, easy to cause myocardial lesions and cardiac rhythm disorders, which is one of the main causes of death.
(7) Some patients develop delayed peripheral neuropathy after acute poisoning.
(8) Blood cholinesterase activity is reduced.
Principles of treatment:
(1) Oral poisoning should be repeated and thorough gastric lavage with alkaline solution or water, avoiding the use of potassium permanganate solution. Skin contaminants are promptly washed repeatedly with soap and water.
(2) detoxification treatment to atropine-based drugs, for moderate and severe poisoning patients should be rapidly atropine after the atropinization continue to give a maintenance dose of 3 ~ 5 d. Oxime-like reenergizing agent is not ideal, the early stage of the application can be appropriate in small quantities.
3) In order to prevent recurrence of the condition, closely observe the condition during the treatment, such as conscious state, pupil, sweating, respiration, heart rate, blood pressure and lungs; strengthen the cardiac monitoring to protect the myocardium and prevent sudden death. After the disappearance of acute toxic symptoms, continue to observe for a week, should not get out of bed too early.
(4) When respiratory muscle paralysis occurs, tracheal intubation or tracheotomy and mechanical ventilation should be performed immediately.
(5) The commercially available Lekomat emulsion contains 5% benzene, so acute Lekomat poisoning is also often accompanied by the effect of benzene, should be given attention and appropriate treatment.
(6) For symptomatic and supportive treatment, see the overview in this section.
Precautions:
The same as for organophosphorus pesticides in general. If the hands or other parts of the skin are contaminated, they can be washed off promptly and adequately with soap without poisoning. Although the volatility of Lego is very low, it is still necessary to prevent inhalation of vapors or aerosols when producing or using.