1. Different etiologies
Esophagitis is a common clinical reflux esophagitis, which is mainly caused by the relaxation of lower esophageal sphincter, the decrease of esophageal clearance rate, and the decrease of resistance to reflux gastric acid and pepsin after long-term exposure to tobacco, alcohol and drugs.
The occurrence of esophageal cancer is the result of long-term effects of many factors, which can be related to the long-term stimulation of rough, irritating and hot foods, the long-term intake of carcinogens such as nitrosamines and mycotoxins, the lack of vitamins A and C, and genetic and oncogene factors.
2. Similar symptoms
Although the causes of the two diseases are different, their clinical manifestations are similar. If they are negligent, they may delay the diagnosis and treatment of esophageal cancer. The typical symptoms of reflux esophagitis are acid reflux and heartburn, and can also be manifested as chest and back pain, foreign body sensation behind the sternum or dysphagia. Dysphagia of reflux esophagitis is partly caused by esophageal spasm and dysfunction, which is intermittent and can occur when eating solid and liquid. A small part is due to long-term esophageal reflux, which leads to fibrous tissue hyperplasia and scar formation, leading to esophageal stenosis, and patients may have progressive dysphagia. Similar to early esophageal cancer, it can also be manifested as burning sensation behind the sternum and foreign body sensation. With the enlargement of the lesion, progressive dysphagia may occur. Therefore, it is difficult to diagnose and differentiate these two diseases only by clinical symptoms.
Esophagitis is a benign lesion, but if it is not treated for a long time, it will develop into a malignant tumor. Long-term chronic inflammation can cause pathological changes of esophageal mucosa, atypical cell proliferation, or the squamous epithelium of the lower esophagus is replaced by metaplastic columnar epithelium, which is called Barrett esophagus. The further development of atypical hyperplasia may become cancer cells. If you can't identify and kill the immune cells of the body, it may become esophageal cancer. In addition, Barrett's esophagus is a precancerous lesion of esophagus, and the risk of esophageal adenocarcinoma will increase by 10-20 times compared with normal people. Therefore, early detection of esophagitis and active intervention are effective anti-cancer measures.
Reflux esophagitis is a clinically curable disease, which can be effectively controlled and cured by gastrointestinal motility drugs (domperidone, mosapride, etc.). ) promote gastric emptying, effective acid suppression therapy (proton pump inhibitor, ranitidine, etc.). ) and long-term maintenance treatment in the later period. In addition, avoiding obesity, keeping the stool unobstructed, and reducing foods that reduce the tension of the lower esophageal sphincter, such as coffee, chocolate, high fat, tobacco and alcohol, can reduce the inducement of reflux esophagitis. In addition, avoiding the intake of spicy, spicy, toxic and harmful substances, eating more fruits and vegetables, and cultivating regular work and rest are all conducive to good health.
Cancer focuses on prevention. If it is found early, it can be completely cured. If the symptoms are not checked regularly, once the best treatment opportunity is missed, it means that there is no cure, so regular outpatient follow-up is very important.
Some types of esophagitis will develop into esophageal cancer! ! ! This must attract everyone's attention. The following knife will explain this problem in detail for everyone!
Gastroesophageal reflux disease refers to heartburn and other symptoms caused by reflux of stomach and duodenal contents to esophagus. According to whether it leads to esophageal mucosal erosion, ulcers are divided into reflux esophagitis and non-erosive reflux disease!
Patients with reflux esophagitis can see erosion and ulcer in their esophagus under gastroscope. When the squamous epithelium of the lower esophagus is replaced by metaplastic columnar epithelium, it is clinically called Barrett esophagus.
Then this Barrett esophagus needs everyone's attention! Under normal circumstances, we can see that the mucosa of the tube is even pink through gastroscopy observation. When Barrett's esophagus occurs, the mucosal epithelium is orange-red, mostly located at the proximal end of the dentate line at the junction of stomach and esophagus, which can be annular, serpentine or island-shaped. After Barrett's esophagus appeared, the probability of patients suffering from esophageal cancer was 10 to 20 times that of normal people. So Barrett's esophagus is also a precancerous lesion of esophageal cancer!
Barrett's esophageal knife gave you a trick up your sleeve.
Use proton pump inhibitors for long-term maintenance treatment, follow up regularly, and closely observe whether Barrett's esophagus is cancerous! Early identification of atypical hyperplasia, found severe atypical hyperplasia or early esophageal cancer, should be promptly surgically removed! Friends, don't be careless
I hope my answer can help you!
Let me talk about the clinical symptoms of esophagitis first: the diagnosis of esophagitis has clinical symptoms such as reflux heartburn. Gastroscope is the most accurate method to diagnose reflux esophagitis. Can judge the severity of reflux esophagitis and whether there are complications, and can perform pathological biopsy to judge whether there are other esophageal diseases.
Pay attention to the complications of esophagitis treatment. Esophagitis can cause Barrett's esophagus, which is a precancerous lesion of esophageal cancer and is likely to develop into cancer. Therefore, when esophagitis is found, regular treatment and regular follow-up are the most effective methods to prevent Barrett's esophagus. Early detection of severe dysplasia or early esophageal cancer and timely surgical resection.
# Healthy Early Bus # # Breeze Plan #
First of all, patients with esophagitis need to know that inflammation and cancer are essentially different. Secondly, not all esophagitis will develop into esophageal cancer. Through regular medication and self-maintenance, most esophagitis can be effectively cured and recovered. Therefore, for esophagitis, correct treatment is king, and don't blindly doubt whether esophageal cancer will occur.
Reflux esophagitis is the most common kind of esophagitis in clinic, which is mainly caused by the relaxation of the lower esophageal sphincter and the reflux of gastric acid and pepsin into the esophagus, resulting in esophageal mucosal injury. When gastric acid and pepsin exist in the esophagus for a long time, it will cause esophagitis or esophageal ulcer.
The clinical manifestations of reflux esophagitis are mostly typical, mainly acid reflux and heartburn, followed by retrosternal pain, dysphagia, radiation pain behind the ear, shoulder and back, etc.
For the treatment of reflux esophagitis, it is mainly to find out the causes of gastric acid reflux, because there are many reasons for gastric acid reflux in clinic, such as obesity, long-term drinking, excessive eating of sweets, high-fat food and psychological factors. In the treatment, it is also necessary to improve the existence of the above-mentioned incentives first, and then routinely take acid inhibitors and drugs to promote gastrointestinal peristalsis.
Let's talk about the cause of esophageal cancer:
1. Long-term intake of carcinogens, such as foods containing nitrosamines, such as pickled pickles, bacon, pickles, ham, etc.
2. Long-term drinking or eating too hot food: Both alcohol and too hot food will cause damage to the esophageal mucosa. When this damage exists for a long time, it may lead to dysplasia of the esophageal mucosa.
3. Genetic factors: Most malignant tumors have certain genetic factors, so people with esophageal cancer in their families must also check them regularly.
The occurrence of esophageal cancer is mostly related to bad life factors: ① long-term consumption of pickled and grilled foods; 2. Bad habits: If you are used to eating hard food and overheated food; 3. Poor diet structure: such as long-term high-fat, high-protein diet, less intake of fresh vegetables and fruits.
Can esophagitis develop into esophageal cancer?
Current research shows that esophagitis has a certain probability of developing into esophageal cancer. If it is a long-term esophagitis, the esophageal mucosa epithelium is repeatedly destroyed and self-repaired. At this stage, the inflammatory stimulation inside the esophagus and the physical and chemical stimulation of external adverse factors may cause some cells or genes to change, leading to the emergence of cancer cells. If the body's immunity declines or the ability to clear cancer cells declines (normal people have strong immunity to clear cancer cells), cancer cells may grow rapidly at this time, and finally show esophageal cancer. Of course, if esophagitis occurs, active intervention can reduce the risk of cancer to some extent. In addition, the current retrospective analysis shows that patients with reflux esophagitis have many times higher risk of esophageal adenocarcinoma than normal people if they have Barret esophagus. At this time, active follow-up and drug intervention (usually long-term proton pump inhibitor treatment) are needed. Most follow-up methods are esophagoscopy.
If you get esophagitis, how to treat it?
The goal of treating esophagitis is to control its reflux and other symptoms, actively treat esophagitis, reduce its recurrence rate and prevent its complications. Its treatment is mostly drug therapy, and commonly used drugs are drugs that promote gastrointestinal motility and acid inhibitors (commonly used proton pump inhibitors, mostly used for moderate and severe patients and maintenance treatment).
Esophageal cancer is a common malignant tumor, and the onset age is over 40 years old, with more males than females. Usually, the incidence rate in the north of China is higher than that in the south. Its main symptom is suffocation, which is getting worse and worse, and finally it is difficult to drink water.
The etiology of esophageal cancer, like other malignant tumors, is not very clear, but after a large number of investigations, it is considered that it may be related to the following factors.
The symptoms of esophagitis are mainly retrosternal pain, but it is not always that esophageal cancer has retrosternal pain and eating difficulties. Some benign esophageal lesions also have similar symptoms. As long as we carry out routine examination according to the doctor's requirements, the diagnosis can generally be made. Esophageal cancer is one of the most common tumors, and the therapeutic effect varies greatly with the course of disease. As long as esophageal cancer is treated early, most patients have hope to be cured. The key issues are early detection, early diagnosis and early treatment.
To prevent the occurrence of esophageal cancer, in addition to actively treating chronic inflammation of esophagus, we should also pay extra attention to daily life:
In recent years, new progress has been made in the study of geographical environment, nitrosamines, mycotoxins and trace elements. In addition, corrosive esophageal stenosis and esophageal spasm may also increase the incidence of esophageal cancer. Therefore, we should pay attention to oral hygiene in daily life and brush our teeth and rinse our mouths frequently; Do not eat food that is too hard or too rough, and make coarse grains carefully, which should be soft and not hard; Chew slowly when eating, and avoid gorging; Drinking tea and soup should not be too hot, wait until it is a little cooler; Avoid eating water or food with high nitrosamine content; Avoid esophageal injury caused by foreign bodies or corrosive chemicals; Develop the habit of eating regularly and quantitatively, don't smoke and drink less. Although this can't guarantee that you won't get esophageal cancer, what is certain is that the chance of getting esophageal cancer will be greatly reduced.
Esophagitis is a common esophageal mucosal disease, which has many classifications, such as reflux esophagitis, fungal esophagitis, viral esophagitis, eosinophilic esophagitis, drug esophagitis, radiation esophagitis and so on. Some esophagitis can develop into esophageal cancer, but it is not inevitable.
1, reflux esophagitis
The risk is average. Mainly to see if it will develop into esophageal ulcer. If the effects of antacids, acid inhibitors, bile adsorbents, mucosal protectants and prokinetic agents are not obvious, the risk is high.
2. Fungal esophagitis
The risk is average. For fungal esophagitis, it is generally more important to pay attention to whether esophageal obstruction and esophageal perforation occur, but when the degree is serious, especially some patients taking immunosuppressive drugs at the same time, the risk is higher.
3, viral esophagitis
Low risk. Basically, as long as drugs are selected according to different virus types, such as herpes simplex virus infection, acyclovir is used; Cytomegalovirus, such as ganciclovir, can control the virus and is not easy to develop further.
4. Eosinophilic esophagitis
The risk is average. Glucocorticoids, antihistamines and proton pump inhibitors are commonly used for treatment.
5, drug-induced esophagitis
Low risk. Does this situation also pay more attention to esophageal stenosis and obstruction? As long as mucosal protective agents, antacids, H2 receptor blockers and proton pump inhibitors are given, it is basically not easy to turn into ulcers and the risk is low.
6, radiation esophagitis
The risk is high. All the consequences caused by radioactive damage are more serious. As we all know, radiation itself can cause cancer.