Efficacy and function of Herba Artemisiae Scopariae
Cholestasis.
The experiment showed that Yinchen decoction, Yinchen Gardenia decoction, Yinchenhao decoction (3: 1.5: 1 of Yinchen Gardenia and rhubarb) and their alcohol extracts all promoted the bile secretion of rats, but they were not obvious enough. Yinchen decoction only slightly reduced the gallbladder contraction (X-ray examination) of normal people, and the volume change was not significant. The water extract and refined concentrated extract of Herba Artemisiae Scopariae (with and without volatile oil removed) have obvious cholagogic effects on dogs with acute gallbladder intubation and chronic gallbladder fistula. It is speculated that the effective components may be water and alcohol-soluble substances, while the effect of volatile sleeve is suspicious or weak. However, it has also been reported that the volatile oil isolated from Nanjing Artemisia capillaris has beneficial gallbladder effect on guinea pigs.
Effect on experimental hepatitis.
The results showed that the decoction of Artemisia capillaris, decoction of Artemisia capillaris and decoction of gardenia rhubarb could all reduce the mortality of mice with carbon tetrachloride-induced hepatitis. The water extract and refined concentrated extract of Artemisia capillaris had more cholagogic effect on dogs with carbon tetrachloride-induced hepatitis than on normal dogs. The decoction of Artemisia capillaris and volatile oil of Artemisia capillaris had no effect on serum transaminase of rabbits with carbon tetrachloride-induced hepatitis, but the latter could increase the food intake of rabbits with hepatitis, but had no effect on improving the mortality and liver cell pathological changes of mice with viral hepatitis. Yinchenhao decoction can promote hepatocyte regeneration in rabbits.
Antipyretic and antimicrobial effects.
Yinchenhao decoction and wormwood extract have antipyretic effects on artificial fever in rabbits. The volatile oils of Artemisia capillaris and its genus Artemisia tridentata and A.nova have obvious inhibitory effects on Staphylococcus aureus in vitro, and also have certain inhibitory effects on Shigella, hemolytic streptococcus, pneumococci, diphtheria, bovine and human tuberculosis. The volatile oil of Herba Artemisiae Scopariae can inhibit the growth of dermatopathogenic fungi in vitro, and its antifungal effective component is artemisia Scoparine.
Hypotensive effect.
Both the water and refined extracts of Herba Artemisiae Scopariae have hypotensive effects. Intravenous injection and duodenal administration of 6,7-dimethoxycoumarin have hypotensive effects on rats, cats, rabbits and dogs, which may be caused by central and visceral vasodilation. The coronary flow of isolated ventricular fibrillation rabbits was significantly increased and the rhythm contraction was restored.
Diuretic action.
The water extract, refined concentrated extract and 6,7-dimethoxy coumarin of Herba Artemisiae Scopariae all showed diuretic effect on dogs. The volatile oil of Herba Artemisiae Scopariae can increase urine volume and change urine color from yellow to clear in rabbits with toxic hepatitis. It can be concluded that Herba Artemisiae Scopariae has diuretic effect.
Relieve itching and refresh the body.
Herba Artemisiae Scopariae also has a good effect of clearing away heat, relieving itching and refreshing the body. Taking a proper amount of decoction of Herba Artemisiae Scopariae in bath water can treat wind itching and scalp itching all over the body.
Relieve jaundice.
This product has the effects of relieving bitterness, clearing away heat due to cold, clearing away dampness and heat in spleen, stomach, liver and gallbladder, and making it come out from urine. It is an important medicine for treating jaundice. If the body and eyes are yellow and the urine is short and red, it is often used with Gardenia, Cortex Phellodendri and Radix et Rhizoma Rhei, such as Yinchenhao Decoction (Treatise on Febrile Diseases); If jaundice is heavier than heat, it can be used with Poria and Polyporus.
Treat neonatal jaundice.
Neonatal jaundice is mostly caused by immature hepatocytes and incomplete compensatory function of the body, which can affect the growth and development of newborns, so it should be treated early. Yinchen Dazao Decoction has the effects of promoting liver cell activity, benefiting qi and promoting fluid production, protecting liver and relieving Huang Zhi. This method has good curative effect, simple usage and no side effects, and is worthy of clinical application.
Side effects of Artemisia capillaris
1, Herba Artemisiae Scopariae is sometimes used as a therapeutic drug by patients with hepatitis B or other liver diseases, but whether Herba Artemisiae Scopariae can be used alone in the treatment of hepatitis B remains to be verified, because there is no Herba Artemisiae Scopariae in the widely used drugs for treating hepatitis B at present. On the contrary, some patients with hepatitis B believe in some charlatans' opinions, so they use Herba Artemisiae Scopariae as a folk prescription in the treatment of hepatitis B. The side effects of this large dose of Herba Artemisiae Scopariae are obvious, and many patients have appeared.
2. High dose application can cause atrioventricular block and indoor block.
3. Excessive dosage can cause dizziness, nausea, epigastric fullness, burning sensation, diarrhea, acute icteric hepatitis, acute biliary tract infection, arrhythmia and even death in severe cases.
The taboo of wormwood
1, it should be emphasized that whether it is medicinal or edible, we should seize the best time to harvest Artemisia capillaris. When firewood is burned? Use it later. Especially when making wormwood porridge, it should be thin and not suitable for those with spleen and stomach deficiency and cold.
2, wormwood, safflower can not be taken together.