1, clearing away heat and promoting fluid production
Trichosanthes root is slightly bitter and slightly cold, and sweet in taste. It can not only clear the lung and stomach meridians, but also promote fluid production to quench thirst. It can be used as reed root and bamboo leaf to treat fever and polydipsia. Compatibility with Radix Adenophorae, Radix Ophiopogonis and Rhizoma Polygonati Odorati can clear away heat, promote fluid production and quench thirst.
2, clearing lung and moistening dryness
Trichosanthes root enters lung meridian, which can clear lung heat and moisten lung dryness.
1, if the symptoms such as lung injury caused by dryness and heat, dry cough with little phlegm and blood in sputum are treated. Often used with Radix Asparagi, Radix Ophiopogonis and Radix Rehmanniae.
2. It can be combined with Ginseng for cough, asthma and hemoptysis due to lung injury caused by dryness and heat.
3. Relieve lung and stomach heat
Trichosanthes root is good at clearing away excess heat in the lung and stomach, and can produce fluid to quench thirst.
1, treating diabetes with accumulated heat, eliminating dryness and damaging body fluid. It is often used with Radix Ophiopogonis, Rhizoma Phragmitis and Radix Angelicae Dahuricae.
2, if the internal heat quenches thirst, both qi and yin are injured, it is often used with ginseng.
4, purging fire and detoxifying
Trichosanthes root can clear away heat, purge fire and detoxify, reduce swelling, expel pus and treat sores, and treat swelling, swelling, heat and pain at the beginning of sores, which can be dissipated when pus is not developed, and can be discharged when pus is developed. It is often used with honeysuckle, angelica dahurica and pangolin.
5. Enhance immunity
Trichosanthin has immunogenicity, can promote the production of immunoglobulin, has strong antigenicity, and can cause allergic reactions in animals. It can make the serum anti-Trichosanthin IgE and IgG antibodies gradually increase in pregnant women. Trichosanthin is a non-specific immune enhancer.
6. Anti-cancer
Trichosanthin has a unique therapeutic effect on choriocarcinoma, which can selectively damage choriocarcinoma cells and melanoma cells. Clinical treatment of malignant hydatidiform mole and choriocarcinoma is effective.
Local injection and intraperitoneal injection of trichosanthin tumor tissue can obviously inhibit the growth of rat WK256, mouse reticulocytoma ascites type, U 14 ascites type and mouse breast cancer. It has obvious inhibitory effect on solid tumor and ascites type of liver cancer in mice, which can reduce the amount of ascites and prolong the survival period. In addition, trichosanthin polysaccharide also has anticancer activity.
7. Antivirus
Trichosanthin has a strong inhibitory effect on the replication and spread of intracellular human immunodeficiency virus in AIDS patients, and reduces the ratio of infected cells to uninfected cells. In recent years, it has been used to treat AIDS.
The main structure of trichosanthin is consistent with acacia protein A chain and castor protein A chain, and both of them have cytotoxic and immunotoxin activities. Using RNA and DNA as substrates, trichosanthin can degrade single strand, unwind and relax double strand, and inactivate ribosome 60S subunit by catalysis to stop protein synthesis. This is of guiding significance to clarify the antiviral mechanism of Trichosanthin.
8, affect blood sugar
The extract of this product can improve the blood sugar of normal, hungry and diabetic rabbits, and increase the contents of liver glycogen and muscle glycogen in hungry rabbits. However, five polysaccharide components isolated from Trichosanthes root can reduce blood sugar in mice.
9. Anti-HIV
In vitro experiments show that trichosanthin can inhibit the replication of HIV in infected immune cells and reduce the number of living cells infected by the virus, and its effective inhibitory concentration is 0.05- 10ug/ml. An egg protein that can inhibit HIV infection and replication is called anti -HIVTA29. Clinical data also show that it has a certain therapeutic effect.
10, side effects of Trichosanthes root
Trichosanthes root can terminate pregnancy, and the mechanism of abortion is as follows: ① it can selectively cause necrosis, coagulation and circulatory disorder of placental syncytiotrophoblast cells; ② Chorionic gonadotropin and steroid hormones were rapidly decreased, and HCG, estradiol, estradiol receptor, estriol, estriol receptor, progesterone and prolactin in maternal plasma and urine were all decreased to varying degrees; ③ Enhance the contraction of uterine smooth muscle. In addition, trichosanthin has anti-early pregnancy effect, which can make the embryo necrosis, liquefaction and finally complete absorption. Its anti-early pregnancy mechanism is mainly related to affecting embryo implantation in endometrium and inhibiting decidua.
1 1, the edible taboo of Trichosanthes root
1, should not be used with aconite herbs.
2, spleen and stomach deficiency and cold stools are taboo.
3. "Notes on Materia Medica Classics": "Lycium barbarum is for it. Evil dried ginger. Achyranthes bidentata, dry paint. Anti-aconite. "
4, "Herbal Classics": "Do not take it if the spleen and stomach are deficient and cold."
5, "Materia Medica Huiyan": "After sweating, those who are thirsty and thirsty should not throw; "Those who are thirsty because of yin deficiency and fire, and the body fluid can't be carried on, can't be generalized."
6, "Ben Jing Feng Yuan": "Anyone who drinks phlegm with a thin spoon is forbidden to use it."
12, the role of Trichosanthes root
1, Trichosanthes root for lily disease and thirst: Trichosanthes root and oyster (boiled) are equally divided. To disperse, drink and take a square inch knife. ("Yong lei zhong Fang")
2, trichosanthes to cure sores and rashes into the eyes: 躵 躵 躵 躵 躵 躵 躵 躵 躵 躵 躵 躵 躵 躵 躵 躵 躵躵ๅ ๅ 365 The same as the fine powder on the top, use a sheep liver, approve it, take the medicine at the end of two dollars, wrap it with hemp, cook it with rice, and eat it frequently. Failing to eat liver, the wet nurse eats more. (Yan Shi Xiao er Fang Lun)
3, trichosanthin to cure thirst: dig deep into the roots of Trichosanthes kirilowii, peel them thick until they are white, cut them in inches, soak them in water for one day and one night, and after five days of easy water, take them out and grind them, and filter them in silk bags, such as powder extraction. Take a square inch knife with water every three or four days, and it can also be used as porridge and cheese, no matter how much, take the difference and stop. (Qian Jin Fang)
4, Trichosanthes root cures bruises, chest pain is unbearable, coughing for many years: Trichosanthes root is not limited, and it costs two yuan each time, and it is adjusted with gypsum tofu halogen. (southern Yunnan materia medica)
5, Trichosanthes root to quench thirst, in addition to gastrointestinal heat: five or two of Trichosanthes root and ginger, two liters of raw Ophiopogon root (with juice) and reed root (cut), and three liters of grass root (cut). Fine cut the five flavors, take a bucket of water, cook three liters, and take three servings. (Qian Jin Fang)
6, Trichosanthes root cures Yangmei tianpao: Trichosanthes root, Ligusticum chuanxiong _ four or two each, Sophora japonica one or two. For the end, rice paste pills are big. Take 70 or 80 pills per hollow ginger soup. ("Simple Unilateral")
7, Trichosanthes root cure black jaundice dangerous disease: a pound of Trichosanthes root, juice Liuhe, take a meal, with yellow water from childhood, if not, then follow. ("Simple Unilateral")
8. Trichosanthes root is used to treat blisters: Trichosanthes root and talc are equally divided. For the end, water is mixed and rubbed. ("Zhiji Fang")
9. Trichosanthes root is used to treat children's sudden yellowing, and the face is yellow: raw roots are smashed with juice, a spoonful of honey, and the two flavors are warm and harmonious. ("Guanglifang")