The efficacy of Soapwort spines swelling and pus
Soapwort is pungent, warm and salty, with swelling and detoxification. The effect of pus discharge. The Materia Medica Repertoire: "Soapberry thorns, pulling out the wind," where the carbuncle is not yet, can lead to dissipate, will be broken, can lead to the head, has been ulcerated can lead to the line of pus. In the ulcer poison medicine for the first important agent, and drain the blood in the wind heat wind poison, so the wind medicine also push this medicine for the opening of the front also."
Searching for wind and pulling out poison
This product is pungent and warm. Xin can disperse, can move blood and qi, into can soften and disperse knots, warm can search for wind, blood circulation and remove blood stasis. It is often used in carbuncles and ringworm sores.
Qi and qi
The taste of pungent and warm, into the liver and kidney meridians, there are qi and blood, warming the meridians and collaterals, blood circulation to eliminate blood stasis, catalyze the fetus clothes down the line of the function, often used in the uterine clothing, jealousy of breasts, amenorrhea, and other evidence.
The role of Soapwort Anti-cancer effect
In vitro test, hot water extract of JTC-26 inhibition rate of 50-70%.
In vivo test, it has the effect of inhibitory activity on turbinate rat sarcoma-180. Decoction with plate hole-punching method, it has inhibitory effect on Staphylococcus aureus and Cattacoccus; water infusion 60g/kg gavage on sarcoma-180 inhibition rate of 32.8%.
Antibacterial and anti-inflammatory effects
Saponaria can inhibit or kill a variety of G+ bacteria and gram-negative bacteria. 3% of the decoction of Saponaria has a bacteriostatic effect on astro nucella and so on. Agar plate hole-punching method test shows that saponaria decoction of staphylococcus aureus, katatococcus and other inhibitory effect; phage screening method suggests that saponaria has anti-phage effect. Soapwort spines can also anti-leprosy bacillus, external treatment of leprosy. Soapwort has significant anti-inflammatory effect.
Immunomodulation
Studies have shown that saponaria can regulate the body's immune system. The ethanol extract of saponaria was used in broiler chickens to observe its effect on the immune function of broiler chickens, the results show that the ethanol extract of saponaria can significantly increase the conversion rate of T and B lymphocytes in broiler chickens in the low-dose group, which has a promoting effect on the immune system, and at the same time, has a role in promoting the growth of the group, but the high-dose group has the opposite effect. Enzyme immunoassay was used to detect the effect of total flavonoids of Saponaria spp. on the release of tumor necrosis factor (TNF) from peritoneal macrophages in ICR mice, and the results showed that total flavonoids of Saponaria spp. had a significant inhibitory effect on TNF in a dose-dependent manner.
Anti-allergic effect
Saponaria can also inhibit mast cell-dependent allergic reactions. The aqueous extract of saponaria inhibited systemic allergic reactions in rats and also significantly inhibited local allergic reactions sensitized by antiDNPIgE. Recent studies have found that this effect is achieved by inhibiting histamine release from mast cells.
Anti-tumor effect
Soapwort has a certain anti-tumor effect, can be used in the treatment of a variety of tumors, has been listed as one of the anti-cancer herbs. Saponaria hot water extract of human cervical cancer culture strain JTC6 inhibition rate of 50% to 70%, on the mouse sarcoma ?180 also has an inhibitory effect. A decoction of soapberry and soapberry twigs in water can be used to treat nasopharyngeal carcinoma. Soapwort also treats papillary carcinoma of soft palate, lymph node metastasis of nasopharyngeal carcinoma and gastric carcinoma, all of which have achieved good efficacy. The methanol extract of Saponaria senegalensis has anti-mutagenic effects as detected by Ames test and SOS coloring lithograph. The methanolic extract of Saponaria senegalensis had a certain inhibitory effect on the growth of cervical cancer U14 in mice, and the mechanism may be related to the inhibition of proliferating cell nuclear antigen (PCNA) and the expression of mutant p53 proteins.
Anti-coagulant effect
Soapwort decoction significantly prolonged the clotting time in mice. In vitro experiments, saponaria decoction significantly inhibited platelet aggregation in rabbits, and significantly reduced the weight of arteriovenous thrombus in rats. At the same time, a single gavage of 15g/kg can significantly extend the rabbit plasma compound calcium clotting time, prothrombin time, white clay partial thromboplastin time, thrombin time, enhanced plasma antithrombin activity; and the rabbit plasma fibrinogen content and euglobulin dissolution time has no significant effect on the vasodilatory function is also no significant effect. It indicates that the mechanism of anticoagulation of Soapwort is to inhibit platelet aggregation, act on endogenous and exogenous coagulation pathway, inhibit thrombin formation, improve antithrombin activity, and related to the role of antithrombin. Using self-designed Soapberry soup (Soapberry, Angelica sinensis, safflower, Rhizoma Ligustici Chuanxiong, Cornus officinalis, Chicken Blood Vine, and Wilsonia) with additions and subtractions to treat all kinds of osteomalacia in 123 cases, with an overall effective rate of 92.7%.
Other effects
Soapwort can reduce blood lipids; can also be used to treat various causes of facial nerve paralysis, neurological headache, trigeminal neuralgia. Had used soap horn thorn sneeze treatment of retention of urine, take a little soap horn thorn powder blown into the nose, the patient then appeared to sneeze, a few voices after the urination of their own under the legacy. With rhubarb saponaria spicata soup half dose retained enema, half dose injected through the gastric tube after clamping the tube for 2h, the treatment until the discharge of more accumulated rotten stools or in the anus defecation defecation maintained for 1 to 2d, the results of the recovery time of the anus defecation (2.4±0.9)d, the time of relief of intestinal obstruction is significantly shorter than the other treatment groups (P
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