Grapefruit is generally acidic, but there are many varieties of grapefruit, some of which have bitter taste and hemp tongue taste, such as Duncan grapefruit. This kind of grapefruit has larger fruit, thicker peel and more seeds. The pulp contains antioxidant naringin, which is slightly bitter. Some grapefruit, which was originally sweet and sour, will also become bitter because of deterioration and decay.