Bitter ginseng, which is distributed all over China, the medicinal part is the dried root of the plant. It contains Picrasidine, oxidized Picrasidine and Picrasinone, which can enhance human immunity and anti-allergy, and is a more commonly used Chinese herbal medicine in clinical practice.
1. Calming asthma and expectorant
Bittersweet mainly produces asthmatic effect through excitation of β-receptor, especially excitation of central β-receptor, relief of bronchial spasm and inhibition of the release of antibodies and slow-reacting substances.
2.Tranquilization
Ginseng alkaloids can significantly strengthen its central inhibitory effect, and can also significantly counteract the psychomotor stimulation caused by central stimulants amphetamine (intraperitoneal injection, 4-6mg/kg) and caffeine (50mg/kg). Picrasidine has a mild analgesic effect alone and significantly increases its analgesic percentage when combined with threshold doses of morphine. It can be used clinically for mild anesthesia.
3. Treatment of inflammation
Chronic hepatitis B is recognized in Chinese medicine as damp-heat stagnation, liver-qi stagnation, liver-spleen deficiency, etc. The important drug for hepatitis treatment, bitter ginseng alkaloid, is extracted from the root of the mountain bean, and the bitter ginseng contains derivatives of bitter ginseng alkaloid. Bitter ginseng decoction can treat hepatitis, reduce aminotransferases, HBsAg, HBeAg turn negative and HBV-DNA titer decrease is an important Chinese medicine.
4. Treatment of dysentery
Bacterial dysentery and amoebic dysentery Chinese medicine identified as damp-heat stagnation, and remove intestinal damp-heat of a lot of traditional Chinese medicines, such as Huanglian, cypress, rhubarb, baihuang, Qinpi, etc., but the bitter ginseng is the treatment of dysentery is the most effective medicine, in order to clear damp-heat, pass the cause of the common method of treatment is mainly. China's traditional Chinese medicine treatment of dysentery is based on bitter ginseng.
5. Anti-allergic
Bitter ginseng contains bitter ginseng alkaloids, bitter ginseng alkaloids, oxidized bitter ginseng alkaloids in 1/5 LD50 dose of the immune function of mice have inhibitory effects. The intramuscular injection of 150mg/kg or 100mg/kg of Picrasidine oxide in rabbits and rats had significant inhibition of passive or active skin allergic reactions and inhibited the formation of serum IgE antibodies in rabbits.
Intraperitoneal injection of oxidized ginseng alkaloids 200mg/kg-d, ****21 days, had a protective effect on the death caused by rapid-onset allergic reactions in mice. From this, it can be seen that bitter ginseng has a certain effect all the time on the allergic reaction caused by the excessive immunity of the autoimmune system, and can be used to prevent and control allergy.
6. Anti-tumor
Bitter ginseng alkaloid has inhibitory effect on mouse Ehrlich ascites carcinoma and sarcoma-180 in vitro and in vivo.
Expanded Information:
Nutritional Value of Bitter Ginseng
Bitter ginseng contains a variety of alkaloids and flavonoids, such as ginseng alkaloids, oxidized ginseng alkaloids, N-oxidized locust alkaloids, locustine alkaloids, dextro-allopatricin, levo-allopatricin, and ginseng neohydroxylinol, bitter ginseng chalcones, bitter ginseng chalcones, ginostemonin, neohydroxypatricinol, etc. etc.
1, the ether extract and alcohol extract of Panax ginseng have strong antibacterial effect on Staphylococcus aureus; Panax ginseng water extract has inhibitory effect on Corynebacterium, Trichophyton mentagrophytes, Trichophyton mentagrophytes, Trichophyton xulans, and Sclerotinia Odoratum.
2. Picrasidine has inhibitory effect on mouse Ehrlich ascites carcinoma and sarcoma-180 in vitro and in vivo.
3. Picrasidine and oxidized picrasidine have obvious whitening effect, and have obvious therapeutic effect on leukopenia caused by cyclophosphamide, X-ray and cobalt-ray irradiation.
4. Picrasidine has an inhibitory effect on auricular swelling induced by croton oil in mice, increase of abdominal exudation in mice induced by acetic acid, and swollen foot pads in rats induced by carrageenan gum.
Reference:Chinese health network - efficacy and effects of bitter ginseng, contraindications and methods of consumption
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