1, drug induced:
Acute pancreatitis can be caused by a large number of adrenal hormones, immunosuppressive drugs, morphine and L- asparagine in the treatment of acute lymphoblastic leukemia.
2. Bacterial or viral infection secondary to other parts of the body:
Such as acute parotitis, pneumonia, bacillary dysentery and tonsillitis.
3, upper digestive tract disease or biliary-pancreatic junction deformity:
Bile returns to the pancreas, leading to pancreatitis.
4. Others:
However, there are still some cases without clear pathogenic factors.
[What are the symptoms of pancreatitis in children]
Etiology of chronic pancreatitis in children 1, chronic calcifying pancreatitis:
(1) Hereditary pancreatitis: It is an autosomal recessive hereditary disease. The gene of hereditary pancreatitis is located in the long arm of chromosome 7. The arginine at the position of trypsinogen 1 17 was replaced by histidine, which led to pancreatic self-digestion and induced pancreatitis.
(2) Tropical (nutritional) pancreatitis in adolescents: it is a common cause of children. It is found in some people with insufficient nutrition intake in tropical areas near the equator in southern India, Indonesia and Africa. The reason is malnutrition, eating cassava flour, containing toxic glycosides.
2, chronic obstructive pancreatitis:
(1) Pancreatic division: The incidence of pancreatic division in the total population is 5% ~ 15%, which is the most common pancreatic malformation. Because the dorsal and ventral pancreatic primordia cannot be fused, the pancreatic tail, pancreatic body and part of the pancreatic head are drained through the relatively narrow accessory pancreatic duct, rather than through the main pancreatic duct.
(2) Abdominal trauma: After abdominal trauma, the recessive injury of pancreatic duct can lead to stenosis, pseudocyst formation and chronic obstruction.
3, idiopathic fibrosis pancreatitis:
Idiopathic fibrosis pancreatitis is rare and may include abdominal pain or obstructive jaundice. Diffuse fibrous tissue hyperplasia can be seen in the gland.
4. Others:
Pancreatitis can occur in children with hyperlipidemia type ⅰ, ⅳ and ⅴ. Transient hyperlipidemia can occur in pancreatitis, so the increase of blood lipid in acute pancreatitis must be re-measured after improvement. Other causes include gallbladder fibrosis, sclerosing cholangitis and inflammatory bowel disease.
[Treatment of infant pancreatitis]
Preventive measures of acute pancreatitis in children. Prevent infectious diseases, such as biliary ascaris, viral infection, septicemia, mycoplasma pneumonia and other diseases.
2, to prevent overeating and malnutrition, so as to avoid gastrointestinal dysfunction, so that the normal activities of the intestine and emptying obstacles, hinder the normal drainage of bile and pancreatic juice, causing pancreatitis.
3. Avoid or eliminate biliary diseases: treat biliary stones in time to prevent intestinal ascaris.
4. Avoid upper abdominal injury, such as endoscopic retrograde pancreatography.
5, prevention and treatment of metabolic disorders, such as hypercalcemia, hyperlipidemia, diabetes and so on.
6. Others: prevention and treatment of alcoholism, trauma, emotion and drugs.
Preventive measures of chronic pancreatitis in children 1, hereditary chronic recurrent pancreatitis should be well consulted.
2, adolescent tropical pancreatitis should prevent malnutrition in protein, a balanced diet.
3. Prevent hyperlipidemia and hypercalcemia.
4. Prevent vitamin D poisoning and overnutrition.
5. At the same time, acute pancreatitis should be thoroughly treated to prevent the disease from being delayed.
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