Methimazole tablets are anti-thyroid drugs. Its mechanism of action is to inhibit peroxidase in the thyroid gland, thus hindering the oxidation of iodide absorbed into the thyroid gland and the coupling of tyrosine, hindering the synthesis of thyroxine (T4) and triiodothyronine (T3). It has been observed in animal studies to inhibit antibody synthesis by B-lymphocytes, reduce the level of thyroid-stimulating antibodies in the blood circulation, and normalize suppressive T-cell function.

Adverse reactions

Rash or pruritus and leukopenia are more common; severe granulocyte deficiency is less common; aplastic anemia may occur with methimazole tablets

Anaphylactic anemia may also occur; it may also result in hyposmia, nausea, vomiting, epigastric discomfort, arthralgia, dizziness and headache, vasculitis, lupus erythematosus-like syndrome. Rarely cause hepatitis, interstitial pneumonia, nephritis and vasculitis involving the kidneys, rarely cause thrombocytopenia, thrombocytopenia or factor VII reduction.

Drug therapy using thiourea drugs to inhibit iodine organicization in the thyroid gland, reducing the synthesis of thyroid hormones. In a small number of patients, drug allergies such as itchy skin, rash, or decreased white blood cells (prone to fever and sore throat) and abnormal liver function may occur within the first two or three months of taking the medication.

You can go to the hospital and tell the doctor about the skin allergy and change a hyperthyroid drug. For example: propylthiouracil.