Grapefruit is a common fruit with a delicious and charming taste. It has the effect of improving appetite. However, there are many things to pay attention to when eating grapefruit. So can't you eat grapefruit when taking medicine? When can't you eat grapefruit? There are many drugs that will react with grapefruit, so you cannot eat grapefruit for a period of time after taking these drugs. Let’s learn more about it below.

1. When can’t you eat grapefruit?

You can’t eat grapefruit while taking medicine. This was reported abroad only a few years ago. About six or seven years ago, the U.S. Food and Drug Administration published a pamphlet that warned patients not to drink grapefruit juice while taking the anti-allergic drug terfenadine or other similar drugs, diphenhydramine hydrochloride. Especially elderly patients should not eat grapefruit or drink grapefruit juice while taking medicine. Because previous studies have shown that the interaction between grapefruit and the anti-allergic drug terfenadine can cause ventricular arrhythmias and even fatal ventricular fibrillation. Foreign pharmacologists have conducted corresponding clinical experiments. The purpose is to observe the difference in drug concentration in the blood of people after drinking grapefruit juice compared with drinking water.

It was found that different people react differently to grapefruit juice. If you drink grapefruit juice and then take the medicine, the blood drug concentration may increase several to hundreds of times compared to taking the medicine after drinking water; if you drink grapefruit juice and then take the medicine after a period of time, it is found that the effect of grapefruit juice on increasing the blood drug concentration can continue. It exists for 24 hours; only after 3 to 7 days, the effect of grapefruit juice gradually disappears. Therefore, for safety reasons, you should avoid eating grapefruit 3 days before taking the medicine and 6 hours after taking the medicine.

Later, studies have mentioned that the ingredients contained in grapefruit may have adverse reactions with other Western medicines. Drugs that are currently considered not to be taken with grapefruit include:

(1) Calcium antagonists, such as nifedipine, nimodipine, nisoldipine, and felodipine;

( 2) Statins, such as Lovastatin, Xuezhikang, Shujiangzhi, and Lipitor;

(3) Valium drugs, such as Serena and Galadin; (4) Immunosuppression agents, such as cyclosporine.

(5) Antihistamines, such as terfenadine; eating the drug with grapefruit will cause the above adverse reactions. However, for safety reasons, patients (especially the elderly) should not take the above drugs when taking them. , it is better to stop eating pomelo.

2. What should not be eaten with grapefruit?

1. Crab: Crabs should not be eaten with grapefruit, otherwise they may irritate the gastrointestinal tract and cause abdominal pain, nausea, vomiting and other symptoms.

2. Carrots, cucumbers, etc.: Carrots, cucumbers, pumpkins, etc. all contain a large amount of vitamin C decomposing enzymes, while grapefruit is rich in vitamin C. If grapefruit is eaten at the same time as the above foods, it will destroy the vitamin C. Nutritional value.

3. Animal liver: Grapefruit is rich in vitamin C, and pig liver is rich in copper, iron, zinc and other ingredients. Once these metal ions meet vitamin C, they will accelerate the oxidation of the metal ions and destroy the original nutritional value. Therefore, it is not advisable to eat grapefruit after eating pork liver.