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What is gastric antrum ulcer? How did this disease come about? What are the symptoms after the onset? How to treat it?
Chronic superficial gastritis refers to chronic inflammatory lesions of gastric mucosa caused by different reasons, which only reach the superficial epithelium of gastric mucosa, mainly confined to the superficial mucosa, that is, the upper 1/3 of mucosal layer. Mucosal congestion, edema or exudation. Mainly found in the antrum of the stomach, but also in the body of the stomach, sometimes accompanied by a small amount of erosion and bleeding.

Blood. Some patients have more erosive lesions in the antrum of the stomach, or are accompanied by different numbers of uplift erosion, which is called chronic erosive or verrucous gastritis. The stomach glands are normal.

What are the clinical manifestations of chronic superficial gastritis?

The most common symptom of chronic superficial gastritis is epigastric pain, and some patients may have no symptoms. Its clinical manifestations are as follows:

1. Upper abdominal pain: the pain is irregular and has nothing to do with diet. Generally, it is diffuse burning pain, dull pain and swelling pain in the upper abdomen. Very few patients show colic and radiate to the back, which is easy to be misdiagnosed as angina pectoris.

2. Hiccup: Due to gastric acid deficiency, gas production by fermentation in the stomach and other factors, gas accumulates in the stomach and causes hiccups.

3. Abdominal distension: Abdominal distension occurs due to food retention, delayed emptying, indigestion and eating undigested food.

4. Loss of appetite: Chronic superficial gastritis often has loss of appetite or sometimes good or bad.

5. Nausea and vomiting: Inflammatory gastric mucosa is accepted, stimulated by biological factors, affected by gastric motility disorder and gastric reverse peristalsis, resulting in nausea and vomiting.

6. Constipation and diarrhea: Most patients have constipation symptoms, and diarrhea is relatively rare.

What are the clinical manifestations of chronic superficial gastritis?

The clinical manifestations of chronic superficial gastritis lack specificity. Different patients have different clinical manifestations. Some patients may have no symptoms and characteristics, and most patients may have dull pain in the upper abdomen, fullness after eating, loss of appetite, belching and so on. And the symptoms can be mild or severe, and they can recur or exist for a long time. The possible clinical manifestations of the disease were summarized.

(1) The most common symptom is epigastric pain, accounting for about 85%. Most patients with chronic superficial gastritis have irregular epigastric pain, which has nothing to do with diet (some patients are comfortable on an empty stomach and uncomfortable after meals). Generally, it is chronic upper abdominal burning pain, dull pain and distending pain. Symptoms are often aggravated by eating cold food, hard food, spicy or other irritating foods, and a few are related to climate change. This antispasmodic antacid for epigastric pain is not easy to relieve.

(2) Abdominal distension, accounting for 70%. It is often caused by gastric retention, delayed emptying and indigestion.

(3) belching, accounting for about 50% of patients. The gas in the patient's stomach increased and was discharged through the esophagus, which temporarily relieved the feeling of fullness in the upper abdomen.

(4) Recurrent bleeding is also a common manifestation of chronic superficial gastritis. The cause of bleeding is the acute inflammatory changes of gastric mucosa based on chronic superficial gastritis.

(5) Others: loss of appetite, acid regurgitation, nausea and vomiting, fatigue, constipation or diarrhea.

(6) Chronic superficial gastritis lacks typical positive signs. There may be tenderness in the upper abdomen during physical examination, and a few patients may have emaciation and anemia.

What are the causes of chronic superficial gastritis?

The pathogenic factors of chronic superficial gastritis have not been fully understood so far, and it has been found that almost any factor that can affect the body can cause chronic superficial gastritis. Among them, the clear reasons are:

(1) Bacteria, viruses and toxins: more common after acute gastritis. Gastric mucosal lesions exist or recur for a long time and gradually evolve into chronic superficial gastritis.

(2) Chronic infection of nasal cavity, oral cavity and pharynx: chronic infection focus of nasal cavity, oral cavity and pharynx, such as alveolar abscess, tonsillitis, sinusitis and other bacteria or their toxins, can repeatedly stimulate gastric mucosa and cause chronic superficial gastritis. Studies have found that 90% of patients with chronic tonsillitis have chronic inflammatory changes in their stomachs.

(3) Smoking: Nicotine is the main harmful component in tobacco. Long-term heavy smoking can make pyloric sphincter relax, duodenal juice reflux, gastric blood vessels contract and gastric acid secretion increase, thus destroying gastric mucosal barrier and leading to chronic inflammatory diseases. According to Ewald, 40% of people who smoke more than 20 cigarettes a day will develop gastric mucosal inflammation.

(4) Drugs: Some drugs, such as salicylic acid, corticosteroids, digitalis, indomethacin, phenylbutazone, etc., can cause chronic gastric mucosal damage.

(5) Irritating food: Long-term consumption of spirits, strong tea, coffee, spicy and rough food, and irregular eating patterns such as hunger or satiety can destroy the protective barrier of gastric mucosa and cause gastritis.

(6) circulatory and metabolic dysfunction: the structural and functional integrity of gastric mucosa and its defense against various injury factors are closely related to adequate mucosal blood flow. Congestive heart failure or portal hypertension makes the stomach stay in a state of blood stasis and hypoxia for a long time, which leads to the weakening of gastric mucosal barrier function, the decrease of gastric acid secretion and the proliferation of bacteria, which is easy to cause inflammatory damage of gastric mucosa. In chronic renal failure, urea is excreted from the gastrointestinal tract, and bacteria or intestinal hydrolases produce ammonium carbonate and ammonia, which causes irritating damage to the gastric mucosa, leading to congestion, edema and even erosion of the gastric mucosa.

(7) Bile or duodenal juice reflux: Bile reflux is an important cause of chronic gastritis, which can be found or diagnosed by fiberoptic gastroscope. Due to the dysfunction of pyloric sphincter or after gastric surgery, duodenal juice or bile can reflux into the stomach, destroy the gastric mucosal barrier and promote H? +and pepsin diffuse back to mucosa, causing a series of pathological reactions, leading to chronic gastritis.

(8) Helicobacter pylori (HP) infection: 1983, Australian scholars Marshall and Warren first isolated HP from gastric antrum mucosa and epithelial cells of patients with chronic gastritis. Since then, many scholars have done a lot of experimental research on patients with chronic gastritis, and HP has been cultivated in the gastric mucosa of 60% ~ 90% patients with chronic gastritis, and then it is found that the infection degree of HP is positively correlated with the inflammation degree of gastric mucosa. Therefore, in 1986, the 8th World Gastroenterology Society proposed that HP infection is one of the important causes of chronic gastritis. The pathogenic mechanism of HP may be mainly through destroying the gastric mucosal barrier, making H+ diffuse reversely, and finally causing gastric mucosal inflammation.

(9) Psychosomatic factors: Being in a state of mental stress, anxiety or depression for a long time due to unhealthy mental health can cause imbalance between sympathetic and parasympathetic nerves. In particular, the long-term excitement of sympathetic nerves will also lead to the dysfunction of gastric mucosal blood vessels, the decrease of gastric mucosal blood flow, the destruction of gastric mucosal barrier, and the formation of chronic inflammatory reaction of gastric mucosa over time.

Prohibited drugs for superficial gastritis

Patients with chronic superficial gastritis are in a state of congestion, edema, punctate bleeding and erosion, so there are certain restrictions on the drugs they take. If you take or use the following drugs by mistake, it will aggravate the damage of gastric mucosa and aggravate the symptoms such as upper abdominal discomfort, nausea and vomiting; In severe cases, it will cause gastric ulcer and imperceptible gastric bleeding, which will make patients unconsciously anemia, physical decline, low resistance, and easy to be complicated with other diseases.

Drugs prohibited for patients with chronic superficial gastritis are:

(1) Salicylic acid: aspirin, sodium salicylate.

(2) Aniline: paracetamol and phenacetin.

(3) Pyrazolinone: Butazone, aminopyrine.

(4) Other anti-inflammatory organic acids: indomethacin and ibuprofen.

(5) Antibiotic: tetracycline.

(6) Glucocorticoids: prednisone, dexamethasone and cortisone.

Chronic superficial gastritis is a common and frequently-occurring disease, which can affect men, women and children, and has a long course of disease, easy recurrence and great influence on health.

There are many drugs for treating chronic superficial gastritis. In the past, analgesics (such as 654-2, propofol, etc. ), antacids (such as metoclopramide, sucralfate) and traditional Chinese medicine have been used, but the long-term effect is not good.

Because the cause of chronic superficial gastritis is not very clear, it is mainly symptomatic treatment. It can be used according to different conditions: ① drugs for protecting gastric mucosa: sucralfate, gastrin, Hericium erinaceus tablets, Maizilin -S, etc. ② Drugs to reduce gastric acid secretion: such as anticholinergic drugs, atropine, propofol, 654-2, etc. H2 receptor blockers, such as cimetidine, ranitidine and famotidine. And prostaglandin e! , Losec, etc. ; ③ Colloidal forceps preparation: Denol, etc. ④ Drugs to promote gastrointestinal peristalsis: metoclopramide, chlorpyrifos, etc. And the newly developed Cisapride. The general treatment schedule is 4-6 weeks. When one drug is ineffective, another drug can be selected or added, and the combination of drugs in the same category should not be selected. It can also be treated with traditional Chinese medicine, which can be treated according to the clinical symptoms and characteristics of patients and combined with etiology and pathology.

Generally, oral ranitidine and gentamicin are effective in treating chronic superficial gastritis with few side effects and low recurrence rate. The specific method is:

(1) ranitidine: 2 tablets each time, daily 1 time, taken orally before going to bed, for 2 weeks and 3 times;

(2) Gentamicin tablets: 2 tablets each time, 3 times a day for 3 weeks. If individual patients have epigastric discomfort after taking gentamicin, they can change to kanamycin, 0.5g each time, and take it orally twice a day.

If the patient has obvious epigastric pain, you can take 654-2 or propranolol, and stop using it after the pain is relieved; If the epigastric fullness is obvious, lactase can be taken for 3 days before ranitidine and gentamicin (each time 1.5-3.0g, 3 times a day). When accompanied by dyspepsia, multi-enzyme tablets were used in combination at 1 week; Patients with severe symptoms, nausea and vomiting and unable to eat should be given gentamicin intravenously and metoclopramide intramuscularly, and then given gentamicin and ranitidine orally after vomiting stops.

The hospital diagnosed me as superficial gastritis, and I felt uncomfortable if I didn't pay attention to eating. My friend said that he had stomach trouble, so he refused to take medicine and insisted on drinking honey water to treat the disease. I held on to more than one friend with the feeling of giving it a try, which was really good. The method is to make a cup of honey water with warm boiled water after getting up every morning (honey and water can be mastered according to your drinking habits), and then have breakfast after more than an hour of activity. I still insist on drinking a cup every day, gradually replacing the habit of drinking tea. I have had inflammation and constipation. (Excerpted from the Internet)

How to recuperate patients with chronic superficial gastritis

General principle: a diet with no stimulation, low fiber content, easy digestion and sufficient nutrition; Eat less and eat more; Relax and keep a good mood while eating.

1, eliminate the reason. Thoroughly treat acute gastritis; Quit smoking and drinking; Avoid irritating food and drugs; Treat chronic oral infection, diet, etc.

2. Eat more soft food. Eat easily digestible food, minimize irritation to gastric mucosa, chew slowly, let the teeth completely grind the food, and make the food fully mixed with gastric juice. Avoid cold, hot and sour and hard food. Eat less and eat more, and make coarse grains carefully. Patients with gastric diseases can eat five meals, and the demonstration examples are as follows:

Breakfast: 50 grams of rice porridge, 50 grams of flower rolls, boiled eggs 1, bean curd 1.

Meal 1: 300g milk with sugar15g biscuits15g.

Lunch: rice soft rice 100g, fried fish fillet 100g, spinach and egg soup.

Meal 2: 300 grams of soybean milk, 0/0 grams of sugar/kloc, and 25 grams of cake.

Dinner: 50 grams of rice porridge, 50 grams of cake, mashed potatoes with minced meat 150 grams.

3. If you have malnutrition or anemia, you should give more eggs and eat more fresh vegetables and animals' livers and kidneys.

4, hyperacidity, concentrated broth and acidic foods should be banned, so as not to cause more gastric acid secretion, milk, vegetable puree, starch, bread, etc. Yes, it's light and salty.

5, people with hypochlorhydria can give thick broth and gravy to stimulate gastric acid secretion, help digestion and promote appetite.

Health-care prescription for chronic superficial gastritis

1, regular life, optimistic, quitting smoking and drinking, not overeating, not hungry.

2, eat less and eat more meals, avoid indigestion and irritating food, such as coffee, spicy things.

3. For those with flatulence, pantothenic acid and belching, take motilium or metoclopramide half an hour before meals.

4. People with stomachache can use painkillers or other stomach medicines with analgesic effect.

5. There are few patients with chronic atrophic gastritis accompanied by malignant gastric cancer, so it is necessary to have a gastroscopy every year.

Which patients avoid eating cold drinks?

(1) Patients with gastric and duodenal ulcer, chronic gastritis, chronic colitis, cholecystitis, chronic diarrhea and dyspepsia should not eat cold drinks. Because the digestive system function of these patients is poor, it is easy to stimulate gastrointestinal mucosa and aggravate the condition after eating cold drinks.

(2) People with dental caries and dentin allergy should not eat cold drinks to avoid toothache.

(3) Patients with hypertension, coronary heart disease and atherosclerosis should not eat a lot of cold drinks. Because, after excessive cold drinks enter the gastrointestinal tract, it will suddenly stimulate the stomach, make blood vessels contract, raise blood pressure, aggravate the condition, and easily induce cerebral hemorrhage.

(4) Patients with pharyngitis, bronchitis, bronchial asthma and arthritis had better not eat cold drinks. Because the stimulation of cold drinks will aggravate the inflammation of the throat or induce cough, or cause the recurrence of old diseases.

(5) People with hyperlipidemia and diabetes should not eat cold drinks. Because cold drinks (ice cream, ice cream, etc. ) contains more sugar, milk, eggs and so on. Eating too much blood sugar will suddenly rise, which is not conducive to the stability of the disease.

Modern medicine believes that the increase of gastric acid secretion and the damage of gastric and duodenal mucosal defense function are two main factors causing peptic ulcer. If you don't eat properly, it will aggravate the condition, affect the healing of ulcer or lead to the recurrence of gastric ulcer. In order to prevent the recurrence of gastric ulcer, we should pay attention to the following points in diet:

● Develop good eating habits and eat regularly.

Most patients with gastric ulcer can do this, but some people have difficulty eating on time because of work or occupation. You can prepare some soda cookies or snacks with you and eat some at the usual time. This can not only ensure that gastric acid secretion will not be too much, but also maintain the rhythm of gastrointestinal function, thus avoiding this factor to induce gastric ulcer.

● Do not eat irritating food.

Because the function of gastric mucosa is affected to some extent after gastric ulcer, some irritating foods may aggravate the condition or induce ulcer recurrence, so spicy, coffee, strong tea, soda, acidic drinks, glutinous rice food, too much fried food and so on should be avoided.

● Don't overeat.

Dining, treating guests and getting together create an atmosphere and opportunities for overeating. Overeating will seriously affect the normal operation of the stomach, and dysfunction will lead to gastric ulcer or recurrence.

● Quit smoking and drinking.

More and more data show that smoking can lead to the recurrence of gastric ulcer. It is reported that the recurrence rate of gastric ulcer in smokers is 75%, so patients with gastric ulcer should quit smoking. Alcoholism can directly hurt the stomach, lead to acute gastritis and gastric ulcer, and induce gastric bleeding, so alcoholism is also a taboo for patients with gastric ulcer.

First, eat less and eat more meals to avoid overeating or hunger. If patients with gastric ulcer eat too much, it will cause excessive dilatation of gastric antrum, increase gastric acid and aggravate the condition; or vice versa, Dallas to the auditorium Therefore, according to the individual's illness and conditions, in addition to three meals a day, you can also add cakes or dry steamed buns with less sugar content for 2 ~ 3 times, especially you can eat more baked steamed buns. Because the moisture in the dried steamed bread is almost completely evaporated after baking, the starch in the steamed bread also becomes digestible dextrin, which can neutralize the gastric acid in the stomach after full chewing, thus reducing the stimulation and corrosion of gastric acid on the ulcer surface, not only alleviating or eliminating pain, but also facilitating the healing of the ulcer surface.

Second, eat digestible foods containing enough calories, protein and vitamins, such as porridge, fine flour, milk, soft rice, soybean milk and vegetable leaves. Patients whose symptoms basically disappear can eat normally, but they should still avoid eating fried foods and celery, leeks, bean sprouts, ham, bacon, dried fish and so on. At the same time, don't eat cold and hard food, especially overheated food, so as to avoid gastric bleeding caused by vasodilation.

Third, patients with gastric ulcer should eat more food without residue. In order to avoid dry stool, they should often eat agar, bananas, honey and other foods that can moisten the intestines.

Fourth, avoid all foods that are too sour and too sweet for the ulcer surface, such as peppers, raw onions, raw garlic, concentrated juice, coffee, wine, strong tea, etc. In addition, patients with gastric ulcer should quit smoking, because nicotine in tobacco can change the pH of gastric juice, disturb the normal activity of gastric pylorus, and induce or aggravate ulcer disease.