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How to use swine fever vaccine correctly
Recently, the author in Hunan, Hubei provinces in some areas to do technical promotion work, and the majority of grass-roots veterinary workers and farmers have exchanged views, not only learned some new things, but also found a number of problems, one of which is their understanding of swine fever vaccine and the use of some incorrect views. The basic immunization (i.e., the first immunization) of piglets mostly uses swine fever spleen shower vaccine, and ordinary vaccine is rarely used, and even individual farmers also use combined vaccine (triple or double) for the first immunization. There are four main types of swine fever vaccines analyzed: splenic vaccine (I), lactating rabbit vaccine (I), cellular vaccine (II) and combined vaccine. Although these four vaccines of swine fever strains are all Chinese lineage swine fever rabbit weakened strain (referred to as C strain), but there is still a certain difference between each other: (1) splenic gonorrhea vaccine, lactating rabbit vaccine and cellular vaccine is a single vaccine for swine fever, the combination of vaccines is generally referred to as the "swine fever - dengue - pneumonic plague triple vaccine" or "swine fever - dengue double vaccine "The single vaccine can be used for basic immunization of pigs, but the combined vaccine is prohibited to be used for the first immunization or pre-weaning immunization of piglets. (2) General seedling generally refers to cellular seedling (the virulence content of not less than 750RID per head is much higher than the virulence content of not less than 150RID per head of tissue seedling), which can not only prevent clinical morbidity, but also protect from subclinical infection, reaching the level of "double protection", so the general immunization of swine fever using swine fever cellular seedling immunization can be used. Therefore, the general immunization against swine fever can be done by using swine fever cell vaccine. (3) Splenic gonorrhea vaccine and lactating rabbit vaccine are rabbit-derived tissue vaccines, which are prepared by using the live tissues of adult rabbits and lactating rabbits, with small yield, high cost and easy to be contaminated. This type of vaccine is preferably not used for pre-milk immunization, and immunization of live swine fever vaccine (rabbit source) in sub-pig herds that have not consumed colostrum may induce more serious vaccination reactions. (4) In emergency immunization against swine fever vaccine, tissue vaccine is preferred to cellular vaccine, probably because some tissue proteins in tissue vaccine, especially lymphokines in lymphosplenic vaccine, are an immune booster. Suggestion (1) For basic immunization of piglets, it is better to use swine fever cellular vaccine, not swine fever tissue vaccine (spleen vaccine and rabbit vaccine), and it is forbidden to use swine fever triple vaccine or double vaccine. Fever vaccine is often used in the second immunization or the first immunization of weaned piglets. (2) In case of swine fever and urgent immunization against swine fever, it is recommended to use swine fever splenic vaccine, which can be used together with transfer factor if necessary. For swine fever immunization, some farmers say: "large doses of swine fever vaccine, a pig injected dozens of copies or even hundreds of copies of the poison to fight the poison, but also did not see any obvious adverse reactions." This has led to the erroneous view that "more injection is better than less" or "more is better than less". Analysis: Whether it is normal immunization against swine fever vaccine or emergency immunization against swine fever vaccine, the use of large doses of swine fever vaccine is a wrong practice, even if the immunization did not produce obvious adverse reactions, but the subsequent negative effects are very terrible. First of all, swine fever vaccine is a live vaccine, large doses of vaccine, invariably injected a large number of viruses into the body, will give healthy pigs buried "latent pathogens" or aggravate the disease in sick pigs. Secondly, the use of large doses of swine fever vaccine not only causes the waste of vaccine and increases the cost, but also affects the ecological changes of swine fever virus and the normal immune ability of the body in the long run, and even produces the phenomenon of "immune tolerance". Secondly, the production process of live swine fever vaccine is sometimes contaminated by Bovine Viral Diarrhea Virus (BVDV), which will reduce the immunity effectiveness of the vaccine, or even immunization failure (this is a problem of swine cell vaccine). The use of swine fever vaccine in large doses under such circumstances will inevitably increase the side effects of the vaccine on the pig. The large dose of swine fever vaccine will cause the pig body to carry poison and detoxification for a long time, and it is difficult for the farm to be purified of swine fever, and even once the farm is sick, swine fever will play a major role. Therefore, the use of swine fever vaccine should be scientific and reasonable, according to the actual situation of quantitative immunization of swine fever vaccine.