The efficacy, function and taboo of Lycium barbarum bark, a Chinese herbal medicine, has a long history of application. Its efficacy and function are very rich, and the dosage should be paid attention to. It is good for us to know its efficacy and function. Have you understood it after reading the efficacy, function and taboo of Lycium barbarum bark?

The efficacy and function of cortex Lycii and the efficacy and function of taboo cortex Lycii

Traditional Chinese medicine believes that cortex Lycii is sweet, cold and moist, which can clear the deficiency heat of lung and kidney, except for sweating bone steaming, and is a good product for relieving deficiency heat and treating bone steaming. According to modern pharmacological analysis, the ethanol extract, water extract and ether residue water extract of Lycium barbarum bark have strong antipyretic effect. The decoction and extract of Cortex Lycii also have the effects of lowering blood sugar and blood lipid.

Effects on cardiovascular system

The infusion, tincture and decoction of Lycium barbarum bark have obvious antihypertensive effect on anesthetized dogs, cats and rabbits, accompanied by slow heart rate and accelerated breathing. Intravenous injection of 0.375g/kg of Lycium barbarum bark injection to anesthetized dogs can reduce their blood pressure to zero and cause them to die, and repeated injection with small dose has no rapid tolerance. The methanol extract of Lycium barbarum bark was injected intravenously into rats. 5g (crude drug) /kg also has obvious antihypertensive activity. During the hypotensive period of cortex Lycii, ECG showed that the heart rate slowed down, the P-R interval prolonged and the T wave decreased. Moderate dose could cause partial or even complete atrioventricular conduction block in guinea pig heart. The hypotensive effect of cortex Lycii may be related to its blocking sympathetic nerve endings and directly relaxing blood vessels, in addition to the central participation. In addition, Lycium barbarum A and Lycium barbarum B have anti-adrenocortical hormone and renin effects, which is also one of their antihypertensive mechanisms.

Hypoglycemic effect

The blood sugar of rabbits was increased for a short time, then decreased for a long time, and it has not recovered after 4 ~ 8 hours. There is no obvious antagonistic effect on hyperglycemia caused by adrenaline injection. The blood sugar of rabbits was also decreased by subcutaneous injection of extract. Another bearded Lycium barbarum root extract can significantly and permanently reduce blood sugar and increase carbohydrate tolerance in rats, and its hypoglycemic effect is due to its guanidine derivatives.

Hypolipidemic effect

Oral administration of Lycium barbarum extract can decrease the total cholesterol content in serum of experimental rabbits, but it has little effect on triglyceride content and liver fat content, while betaine has anti-fatty liver effect.

Antipyretic effect

The water extract of Lycium barbarum bark, ethanol extract and ether residue water extract have obvious antipyretic effect on rabbits with artificial fever. The ether extract and the water extract of the residue after ethanol extraction have no effect. Its antipyretic effect is weaker than that of aminopyrine, which is about equal to other antipyretics.

Pathogenic microorganism action

Cortex Lycii decoction has strong inhibitory effect on typhoid Bacillus, paratyphoid Bacillus A and Shigella flexneri, but has no effect on Staphylococcus aureus. It can inhibit the cytopathic effect of influenza A virus strain 68- 1; It is an inefficient bacteriostatic drug for mycobacterium tuberculosis.

Other functions

The decoction of Lycium barbarum bark can inhibit the production of interleukin -2 by spleen cells of normal mice. It can significantly improve and enhance the decrease of interleukin -2 production in spleen cells of mice caused by cyclophosphamide; It can inhibit the abnormal production of interleukin -2 caused by azathioprine. Lycium barbarum bark injection (100%) has remarkable exciting effect on isolated uterus of pregnant rats and mice.

Bone skin taboo

People with spleen and stomach deficiency and cold should not take it.

Introduction to Medicine: "Avoid iron."

"Materia Medica": "Deficiency and fire are strong and spleen and stomach are weak, so those who eat less and have diarrhea should reduce it."

"Materia Medica Zhengzheng": "Don't use fake heat."

Clinical Application of Cortex Lycii in Treating Hypertension

Take fresh Lycium barbarum root bark or whole root twice a day (dry product 1 twice), decoct in water and take it separately for 30 days as a course of treatment. Thirty-six patients in1~ 3 stage were observed, 20 cases were markedly effective (according to the standards formulated by Lanzhou Cardiovascular Conference in), 5 cases were effective, and 1 1 case was ineffective. Among them, 3 cases in phase I were all effective; The third stage has the lowest curative effect, and the effective rate is 62%. The fastest time of curative effect is 4 hours, and the slowest is 7 days. All patients' self-conscious symptoms were improved to varying degrees. There was no postural hypotension and other side effects.

Treat young verruca plana, palmoplantar verruca, and generalized eczema.

Cortex Lycii is made into 10% injection, with 2 ~ 3 ml each time, 2 ml of autologous blood added, and intramuscular injection twice a week, with 10 as a course of treatment. If you are not cured, you can continue a course of treatment. 7 cases of young verruca plana were treated, 6 cases were cured, 1 case improved, and most of the rash disappeared; Generalized eczema 12 cases, 9 cases were cured, 2 cases were improved, and 1 case was ineffective. Some patients get better after 2 ~ 4 times of treatment, and recover after 5 ~ 6 times. A few patients felt mild headache and facial flushing shortly after injection.

Treat pulpitis pain

Take Cortex Lycii 1 2 and add 500 ml of water, decoct to 50 ml, filter and fill the cleaned nest with a cotton ball dipped in liquid medicine. After treatment 1 1 cases, all of them have obvious analgesic effect. Some drugs stop the pain after 1 min.

Treatment of malaria

Take fresh cortex Lycii 1 2 and tea 1 money, decoct in water and take it 2-3 hours before the attack. It was tried on 150 patients, of which 145 patients all controlled their seizures, and some of them took 1 dose to take effect.

Treat internal injury fever and infection fever, not for cold fever.

This product has the effect of relieving heat and lowering temperature, and can be used for fever due to immune diseases, tumor, summer functional fever, chronic infectious fever, tuberculosis fever, infectious fever due to lung and bronchus, etc. According to TCM syndrome differentiation, it is fever due to internal injury, and infectious fever due to damp-heat, phlegm-heat, excess heat and blood heat. It can be used with Artemisia annua and Anemarrhena. However, its heat-relieving effect is weaker than gypsum and stronger than Artemisia annua. The same use can increase efficiency.