The Rh blood group system, which contains five antigens, namely C, c, D, E and e. Any human blood erythrocyte containing the D antigen (also known as the Rh antigen) is Rh-positive, otherwise it is negative. This makes the four main blood types of red blood cells A, B, O and AB have been found in people, and are respectively divided into two are classified as Rh positive and negative two.

With continuous research on the Rh blood group, it is believed that the Rh blood group system may be the most complex of the red blood cell blood groups.There are no natural antibodies to the Rh blood group, and most of the antibodies are generated by blood transfusions (Rh-negative people are fed Rh-positive blood) or immunization during pregnancy (Rh-negative mothers are pregnant with an Rh-positive fetus), which is of great clinical significance. Once antibodies are formed, a serious transfusion reaction can occur if Rh-positive blood is reintroduced. Re-conception of an Rh-positive fetus can result in hemolytic disease of the newborn.

Expanded Information

The bloodgroupsystem is a grouping that categorizes red blood cells according to their homozygous (or phenotypic) antigenic relationships on the red blood cell membrane. Erythrocyte antigenic determinants can elicit either a homozygous or heterozygous immune response. In the identification of human blood groups, the agglutination reaction is usually performed with specific human antisera.

Each blood group system is inherited independently, and most of the genes controlling a blood group system are on the same chromosome. There are 35 human blood group systems discovered, but the ABO blood group system and the Rh blood group system are the most clinically important in clinical trials.

Baidu Encyclopedia - Rh Positive Blood Group