Contents 1 Pinyin 2 English reference 3 Overview 4 Latin name 5 English name 6 Alias ??of Lianqiancao 7 Source 8 Original plant form 9 Origin 10 Harvesting and initial processing 11 Meridian distribution of nature and flavor 12 Efficacy and indications 13 Chemical composition 14 Pharmacological effects of Lianqiancao 15 Pharmacopoeia standards of Lianqiancao 15.1 Product name 15.2 Source 15.3 Properties 15.4 Identification 15.5 Inspection 15.5.1 Impurities 15.5.2 Moisture 15.5.3 Total ash 15.5.4 Acid-insoluble ash 15.6 Leachate 15.7 Lianqiancao slices 15.7.1 Preparation 15.7.2 Identification and inspection 15.7.3 Extracts 15.7.4 Nature, flavor and meridians 15.7.5 Functions and indications 15.7.6 Usage and dosage 15.7.7 Storage 15.8 Source 16 References attached: 1 Prescriptions using the Chinese medicine Lianqiancao 2 Chinese patent medicines using the Chinese medicine Lianqiancao 3 Lianqiancao in ancient books 1 Pinyin

lián qián cǎo 2 English reference

Nepeta glechoma Benth. [Landau Chinese-English Dictionary]

glechomae herba [Xiangya Medical Professional Dictionary]

longtube ground ivy herb [Xiangya Medical Professional Dictionary]

Herba Glechomae (拉) [Traditional Chinese Medicine Terminology Approval Committee. Traditional Chinese Medicine Terminology (2004)]

longtube ground ivy herb [Traditional Chinese Medicine Terminology Approval Committee. Traditional Chinese Medicine Terminology (2004) ] 3 Overview

Lianqiancao

Lianqiancao is the name of a Chinese medicine. Published "Questioning Materia Medica". It is the dry aerial part of Glechoma longituba (Nakai) Kupr. of the Lamiaceae plant [1].

"The Pharmacopoeia of the People's Republic of China" (2010 edition) records the pharmacopoeia standards of this traditional Chinese medicine. 4 Latin name

Herba Glechomae (La) ("Terms of Traditional Chinese Medicine (2004)") 5 English name

longtube ground ivy herb ("Terms of Traditional Chinese Medicine (2004)") 6 Alias ??of money grass

Money grass, large-leaf money grass, and Touguxiao.

Money grass, water chestnut grass, wall grass, money mint, Jiangsu money grass, bunch of money [2]. 7 Sources

Glechoma longituba is the whole plant of Lamiaceae plant Glechoma longituba (Nakai) Kupr.[2].

Glechome longituba is the above-ground part of the Lamiaceae plant Glechome longituba (Nakai) Kupr. 8 Original plant form

Perennial herb. The stem is thin, square, covered with fine pubescence, with the lower part prostrate and the upper part upright. The leaves are opposite, kidney-shaped to round-heart-shaped, 1.5-3cm long, 1.5-5.5cm wide, with circular serrations on the edges, hairy or nearly hairless on both sides, and glandular spots below; the petiole is 1-2 times as long as the blade. The inflorescences are axillary, with 2 to 6 flowers in each whorl; the bracts are spiny and awn-shaped; the calyx is bell-shaped, 7-10mm long, the calyx teeth are narrowly triangular-lanceolate, the top is awn-shaped, and there are hairs and glandular spots on the outside; the corolla has 2 lips. Shape, light blue to purple, 1.7-2.2cm long, lower lip with dark spots, middle lobes kidney-shaped; stamens 4, with branched chambers.

Nutlets are oblong and brown. The flowering period is from March to April, and the fruiting period is from April to June.

Grows by rivers, roadsides, forest meadows, and hillside understory. 9 Origin

Lianqiancao is mainly produced in Jiangsu, Zhejiang and other places [2].

It is produced in all parts of the country except northwest and Inner Mongolia. 10 Harvesting and initial processing

Harvest from spring to autumn, remove impurities and dry in the sun. 11 Meridian distribution of nature and flavor

Lianqiancao tastes bitter, pungent, and slightly cold in nature; it enters the liver, gallbladder, and bladder meridians [2]. 12 Efficacy and Indications

Lianqiancao has the effects of clearing away heat and diuresis, dispelling wind and detoxifying, dispersing blood stasis and reducing swelling [2].

Treat urinary tract infections, urinary tract stones, nephritis edema, jaundice, colds and coughs, cerebral leakage, rheumatic joint pain, and malaria [2]. Decoct and take 9~30g[2].

To treat poisonous snake bites, mumps, sores, bruises, bruises, pound and apply fresh product; scabies, eczema, decoct and wash with water [2].

Lianqiancao has the effects of clearing heat and detoxifying, diuresis and stone removal, dispersing blood stasis and reducing swelling. Used for urinary tract stones, liver and gallstones, damp-heat jaundice, and bruises. 13 Chemical composition

The stems and leaves of Lianqiancao contain volatile oil. The main components are pinocamphone, menthone, isomenthone, pulegone, etc., and also contain ursolic acid. , succinic acid.

The whole plant of Lianqiancao contains proline and other amino acids [2].

Lianqiancao contains volatile oil, the main component of which is Pinocamphone, as well as pinene, menthol, limonene, etc. [2].

Desmodium also contains ursolic acid, bile, tannins, bitterness, stachyose, potassium nitrate, etc. [2]. 14 Pharmacological effects

Lianqiancao decoction has obvious diuretic and choleretic effects on rats and rabbits [2]. In vitro, it has inhibitory effects on Staphylococcus aureus, typhoid fever, dysentery, Pseudomonas aeruginosa and other bacilli [2].

Desmodium extract can resist ulcers in mice [2].

The water decoction of Lianqiancao can lower blood pressure and inhibit hepatitis B surface antigen [2]. 15 Pharmacopoeia standard of Lianqiancao 15.1 Product name

Lianqiancao

Lianqiancao

GLECHOMAE HERBA 15.2 Source

This product is lip-shaped The dry aerial parts of Glechoma longituba (Nakai) Kupr. Harvest from spring to autumn, remove impurities and dry in the sun. 15.3 Characteristics

This product is 10-20cm long and sparsely pubescent. The stem is square-cylindrical, thin and twisted; its surface is yellow-green or purple-red, and there are no roots at the nodes; it is brittle and easy to break, and its cross-section is often hollow. The leaves are opposite, mostly wrinkled, kidney-shaped or nearly heart-shaped when flattened, 1-3cm long, 1.5-3cm wide, gray-green or green-brown, with crenulate edges; petioles are slender, 4-7cm long. The inflorescences are axillary and the corolla is 2-lipped, up to 2cm long. The rubbing gas is fragrant and slightly bitter. 15.4 Identification

(1) Powder gray-green, multicellular non-glandular trichomes, often with one or several cells overflowing and shrinking, and single-cell cone-shaped non-glandular trichomes. Adenosquamous head 8 cells. The head of the small glandular trichome is single-celled; the stalk is single-celled. The cell walls of the lower leaf epidermis are wavy and curved. Air hole straight axis type. The hanging walls of the upper epidermal cells are wavy and have a fine keratin texture. The diameter of threaded conduit and reticulated conduit is 20~30μm.

(2) Take 2.5g of this product powder, add 50ml of 70% methanol, heat and reflux for 1 hour, filter, and evaporate the filtrate to dryness. The residue is treated with petroleum ether (30~60℃) and dichloromethane in sequence. 5ml each, soaked for 3 minutes respectively, discard the petroleum ether and methylene chloride liquid, evaporate to dryness, add 5ml of water to the residue to dissolve, pass it through a D101 macroporous adsorption resin column (inner diameter: 1.5cm, column height: 12cm), wash with 80ml of water Remove the water, discard the water, and then elute with 150 ml of 35% ethanol. Discard the eluate, and then elute with 40 ml of 70% ethanol. Collect the eluate, evaporate to dryness, and add 2 ml of methanol to the residue to dissolve it, and use it as a test sample. solution. Another 2.5g of Lianqiancao reference medicinal material was taken, and the reference medicinal material solution was prepared in the same way.

Then take the luteolin reference substance, add methanol to make a solution containing 0.1mg per 1ml, and use it as the strength reference substance solution. According to the thin layer chromatography (Appendix VIB) test, take 2 to 6 μl of each of the test solution and control medicinal material solution, and 2 μl of the reference solution, and place them on the same silica gel G thin layer plate respectively. Use cyclohexane ethyl acetate-formic acid to (8:9:0.5) is the developing agent, unfold, take out, dry, spray with 3% aluminum trichloride ethanol solution, heat at 105°C for several minutes, and inspect under ultraviolet light (365nm). In the chromatogram of the test product, fluorescent spots of the same color appear at positions corresponding to the chromatogram of the control medicinal material and the reference substance. 15.5 Inspection 15.5.1 Impurities

shall not exceed 2% (Appendix IXA). 15.5.2 Moisture content

shall not exceed 13.0% (Appendix IXH Method 1). 15.5.3 Total ash content

shall not exceed 13.0% (Appendix IXK). 15.5.4 Acid-insoluble ash

shall not exceed 3.0% (Appendix IXK). 15.6 Leachables

Determine according to the hot soak method under the alcohol-soluble leachables determination method (Appendix X A), using dilute ethanol as the solvent, not less than 25.0%. 15.7 Lianqiancao pieces 15.7.1 Processing

Remove impurities, wash, cut into sections and dry.

This product is in irregular segments. The stem is square, with a yellow-green or purple surface. The cut surface is often hollow. The leaves are opposite, mostly wrinkled, gray-green or green-brown. The inflorescences are axillary and the corolla is lip-shaped. The rubbing gas is fragrant and slightly bitter. 15.7.2 Identification and inspection

Same as medicinal materials (except for impurities). 15.7.3 Extract

Same as medicinal materials. 15.7.4 Nature, flavor and meridians

Pungent, slightly bitter and slightly cold. Returns to the liver, kidney, and bladder meridians. 15.7.5 Functions and indications

It can relieve dampness and relieve stranguria, clear away heat and detoxify, dissipate blood stasis and reduce swelling. It is used for hot stranguria, stone stranguria, damp-heat jaundice, sores, swelling and pain, and bruises. 15.7.6 Usage and dosage

15～30g. Appropriate amount for external use, decoction and wash. 15.7.7 Storage

Store in a dry place to prevent mildew. 15.8 Source