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What you need when making yogurt is () A. Penicillium B. Yeast C. Escherichia coli D. Lactic acid.
Yogurt is made from fresh milk fermented by lactic acid bacteria. After fermentation by lactic acid bacteria, the original lactose in milk is converted into lactic acid, which is easy to digest, so it has a sweet and sour flavor, and its nutritional composition is roughly the same as that of fresh milk. It can be seen that D meets the meaning of the question.

So choose: D.