1, different sources: mother-of-pearl is extruded from shellfish powder or polished from natural seawater; pearls are produced in the shellfish and mother-of-pearl mollusks in the body, more rare.

2, different nature: mother-of-pearl belongs to the shellfish; pearls belong to the organic gemstones.

3, the appearance of different: mother-of-pearl has silver-white, golden, peacock green and other colors; pearls generally have white, gold, black three colors.