"Nifedipine was replaced three years ago, and before that it was always amlodipine, and it was fine." Looking at the bed still in a coma due to cerebral hemorrhage, Wang's wife wiped her tears and said to the doctor.
61-year-old Wang suffered from high blood pressure has been more than ten years, three years ago, one day, because a little dizzy, went to the local clinic, the doctor let him contain a piece of nifedipine, did not expect the blood pressure quickly down, from then on, the old Wang felt that the nifedipine blood pressure effect is the best, and went home to his family to tell this matter.
But it did not occur to me that a few days ago, the old king in the home to watch TV, is watching the time, the mind a black, straight down, his wife saw the situation scared, and rushed to the old king sent to the hospital, because it was too late, after the rescue of the old king's life is saved, but the sequelae of cerebral hemorrhage so that the old king is still unconscious at this moment.
The doctor explained: A large part of the cause of the brain hemorrhage is due to the wrong use of antihypertensive drugs.
Wang's wife is a little confused, are clearly nifedipine are written on the antihypertensive drugs, how can you still eat the wrong one?
Obviously two are antihypertensive drugs, why is one eaten in peace, but one let the old king into the hospital?
Nifedipine and amlodipine are in the same class of antihypertensive drugs, and there's not much difference in their effectiveness, but nifedipine is a short-acting antihypertensive drug, and needs to be taken three times a day to ensure that your blood pressure is up to the mark 24 hours a day, but it's very fast, and once upon a time, doctors used to take it as a first-aid drug for hypertensive patients.
Amlodipine, on the other hand, is a long-acting antihypertensive medication, and you only need to take it once a day to ensure that your blood pressure is up to par for 24 hours. The first time I saw this, I was able to get the ball rolling, and I was able to get the ball rolling, and I was able to get the ball rolling, and I was able to get the ball rolling, and I was able to get the ball rolling.
Nifedipine and amlodipine are both commonly used first-line antihypertensive drugs. Both belong to the "diphenhydramine class", which is a dihydropyridine calcium channel blocker class of antihypertensive drugs.
The difference between these two drugs is as follows:
1. Time of onset and duration
Nifedipine peaks at 1 to 2 hours, and has a half-life of 2.5 to 3 hours. The half-life of the drug is 2.5 to 3 hours, so it's usually necessary to take it 3 times a day, and nifedipine works fast and disappears fast, which can lead to dramatic fluctuations in blood pressure and more cardiovascular damage.
In order to lower blood pressure, long-term use of nifedipine alone is also susceptible to sudden death, and the first-generation generic tablets of nifedipine have been banned for long-term use, and are only used for emergency blood pressure lowering in hypertensive crisis situations. Even the processed second-generation nifedipine controlled-release tablets, the release of the active ingredient is still relatively fast, take two times a day, an average of three days can be a smooth lowering of blood pressure.
Amlodipine is a drug that peaks in 6 to 12 hours and has a half-life of 35 to 50 hours, and can be taken once a day to achieve a sustained reduction in blood pressure. Because of the long duration of the drug, the release rate is uniform, and the side effects are relatively few, but the patient will not be able to lower his blood pressure smoothly until 1 to 2 weeks after the drug is administered.
2. Indications
Nifedipine Controlled-Release Tablets can be used to treat hypertension and coronary heart disease, and can also be used in pregnancy and breastfeeding, but prolonged use of this drug can cause a significant increase in the level of blood uric acid.
Amlodipine can be used for the treatment of hypertension, chronic stable angina and angina pectoris, can not be used in pregnancy, breastfeeding women need to stop breastfeeding, for blood uric acid almost no effect.
3. Missed dose of different effects on blood pressure
Nifedipine controlled release tablets short half-life, in the case of adherence to take the drug can maintain a relatively good antihypertensive effect, but missed a dose, you can make the complete loss of its
Amlodipine has a long half-life, and studies have shown that there is no significant difference in blood pressure between patients who miss 1 or 2 doses and those who don't, so patients who have been taking amlodipine for a long time don't miss a dose once in a while.
4. Other differences
Some clinical studies have proved that the probability of adverse reactions to nifedipine controlled release tablets is slightly higher than that of amlodipine, and the common adverse reactions are oedema, headache, and flushing.
Small doses of nifedipine do not affect blood pressure when dilating coronary arteries and can be used as an antianginal drug, but because it raises blood uric acid levels, the drug of choice is amlodipine in gout patients with hypertension and angina pectoris at the same time.
If you want to control blood pressure scientifically, it is not enough to rely on medication alone, but daily life behaviors should also be followed.
Three, control blood pressure, scientific habits can not be less
1, move up
A study shows that every time you do 1 hour of exercise, can make the blood pressure mercury lower 4 ~ 9mm . Many people with high blood pressure exercise very little, so if you wish to keep your blood pressure well under control, talk to your doctor and develop an exercise program that fits your situation.
2, low-salt diet
Sodium in salt affects blood pressure, and a high-salt diet is one of the main causes of hypertension in China. Excessive sodium intake can increase blood pressure, so it is necessary to reduce sodium intake to control blood pressure.
Dietary Guidelines for Chinese Residents in the healthy population per daily salt intake should be less than 6 grams, the hypertensive population daily salt intake should be less than 3.75 grams, in addition to cooking salt, a lot of food in the hidden salt should be noted.
3, Weight loss
Obesity and hypertension is very close, a study has proved that, for the obese people, weight loss of 3.5KG, can reduce blood pressure. In addition to looking at the weight figures, waist circumference is also very important, too much fat in the waist will affect the abdominal organs, easy to consume high blood pressure. Male waist circumference should be less than 101.6 centimeters, female waist circumference should be 88.9 centimeters or less.
4, Less alcohol
Alcohol affects blood pressure, excessive drinking will induce the occurrence of high blood pressure, Specific amount can be white wine (40 ), men 84g, women 42g. height white wine (50 ), men 56g, women 28g. beer: men 680g, women 340g. Wine: 226g for men, 113g for women.
For people with high blood pressure, the medication should follow the doctor's instructions, in addition to the usual self-monitoring of blood pressure, to the hospital on a regular basis, the doctor can decide whether to adjust the medication according to the situation, will be very good control of the blood pressure.
#39 Health Super Team ##Plan Breeze#
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